PT2286794T - Uso de lipossomas catiónicos contendo placlitaxel - Google Patents
Uso de lipossomas catiónicos contendo placlitaxelInfo
- Publication number
- PT2286794T PT2286794T PT101807501T PT10180750T PT2286794T PT 2286794 T PT2286794 T PT 2286794T PT 101807501 T PT101807501 T PT 101807501T PT 10180750 T PT10180750 T PT 10180750T PT 2286794 T PT2286794 T PT 2286794T
- Authority
- PT
- Portugal
- Prior art keywords
- paclitaxel
- cationic liposomes
- liposomes
- cationic
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title 1
- 125000002091 cationic group Chemical group 0.000 title 1
- 239000002502 liposome Substances 0.000 title 1
- 229960001592 paclitaxel Drugs 0.000 title 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03023539 | 2003-10-15 | ||
| EP04000361 | 2004-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2286794T true PT2286794T (pt) | 2016-07-13 |
Family
ID=34524705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT101807501T PT2286794T (pt) | 2003-10-15 | 2004-10-15 | Uso de lipossomas catiónicos contendo placlitaxel |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080063699A1 (enExample) |
| EP (2) | EP2286794B8 (enExample) |
| JP (2) | JP5645340B2 (enExample) |
| AU (1) | AU2004283464B8 (enExample) |
| CA (1) | CA2542217C (enExample) |
| DK (1) | DK2286794T3 (enExample) |
| ES (1) | ES2574231T3 (enExample) |
| HU (1) | HUE028648T2 (enExample) |
| PL (1) | PL2286794T3 (enExample) |
| PT (1) | PT2286794T (enExample) |
| WO (1) | WO2005039533A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| NZ595313A (en) | 2005-02-18 | 2013-03-28 | Abraxis Bioscience Llc | The Use Of Nanoparticles Comprising Rapamycin Or Taxane In The Treatment Of Proliferative Diseases |
| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| JP5700909B2 (ja) * | 2005-05-04 | 2015-04-15 | メディゲーネ アクチエンゲゼルシャフトＭｅｄｉＧｅｎｅ ＡＧ | パクリタキセルを含む陽イオン性リポソーム製剤を投与する方法 |
| CN101257891A (zh) * | 2005-09-01 | 2008-09-03 | 比奥里波克斯公司 | 包含抗组胺剂以及皮质类固醇的脂质体组合物及其在制备治疗鼻炎以及相关疾病的药物中的用途 |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| KR100658436B1 (ko) * | 2005-12-09 | 2006-12-27 | 한국화학연구원 | 아데노실코발라민 함유 피부질환 치료용 외용제 조성물 |
| RU2448697C2 (ru) * | 2006-03-22 | 2012-04-27 | Медигене Аг | Лечение рака молочной железы, негативного по трем рецепторам |
| DE602007007618D1 (de) * | 2006-05-18 | 2010-08-19 | Univ Muenchen L Maximilians | Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis |
| BR112012024590A2 (pt) | 2010-03-29 | 2016-05-31 | Abraxis Bioscience Inc | métodos de reforço da liberação de fármaco e da eficácia de agentes terapêuticos |
| RU2016119999A (ru) | 2010-03-29 | 2018-11-08 | АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи | Способы лечения онкологических заболеваний |
| EP2394640A1 (en) | 2010-05-21 | 2011-12-14 | MediGene AG | Improved liposomal formulations of lipophilic compounds |
| JP6257324B2 (ja) | 2010-06-04 | 2018-01-10 | アブラクシス バイオサイエンス， エルエルシー | 膵臓がんの処置方法 |
| US20130209550A1 (en) | 2010-07-28 | 2013-08-15 | Life Technologies Corporation | Anti-Viral Azide Containing Compounds |
| US20120028335A1 (en) | 2010-07-28 | 2012-02-02 | Life Technologies Corporation | Anti-viral azide-containing compounds |
| JP6112512B2 (ja) * | 2010-12-01 | 2017-04-12 | レクシ ファーマ インコーポレイテッド | 難治性癌を治療するための方法 |
| HRP20250981T1 (hr) | 2011-05-24 | 2025-10-24 | BioNTech SE | Individualizirana cjepiva protiv raka |
| AU2013212068B2 (en) | 2012-01-26 | 2018-02-15 | Life Technologies Corporation | Methods for increasing the infectivity of viruses |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| EP2925348B1 (en) | 2012-11-28 | 2019-03-06 | BioNTech RNA Pharmaceuticals GmbH | Individualized vaccines for cancer |
| DE102013009744A1 (de) * | 2013-03-26 | 2014-10-02 | Forschungszentrum Jülich GmbH | Fusionsmischung zur lipidhaltigen Membranmodifikation einer beliebigen Lipidmembran, einer Zellmembran, einem Bestandteil einer Zellmembran oder einer von den übrigen Zell- Bestandteilen getrennten Zellmembran in vivo oder in vitro |
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| WO2016045732A1 (en) | 2014-09-25 | 2016-03-31 | Biontech Rna Pharmaceuticals Gmbh | Stable formulations of lipids and liposomes |
| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| EP3302423B1 (en) | 2015-06-04 | 2022-05-25 | Crititech, Inc. | Particle production system and particle collection device |
| KR102742522B1 (ko) | 2015-09-16 | 2024-12-12 | 디에프비 소리아, 엘엘씨 | 약물 나노입자 전달체 및 이의 제조방법 |
| WO2017059902A1 (en) | 2015-10-07 | 2017-04-13 | Biontech Rna Pharmaceuticals Gmbh | 3' utr sequences for stabilization of rna |
| WO2017176628A1 (en) | 2016-04-04 | 2017-10-12 | Crititech, Inc. | Methods for solid tumor treatment |
| EP3538074B1 (en) * | 2016-11-11 | 2023-07-26 | Western University Of Health Sciences | Methods of treating upper tract urothelial carcinomas |
| TWI852903B (zh) * | 2017-01-05 | 2024-08-21 | 杏國新藥股份有限公司 | 胰臟癌治療 |
| JP2020514359A (ja) | 2017-03-15 | 2020-05-21 | ディーエフビー ソリア リミテッド ライアビリティ カンパニー | タキサンのナノ粒子を用いる皮膚悪性腫瘍処置のための局所療法 |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| BR112019023948A2 (pt) | 2017-06-09 | 2020-06-09 | Crititech Inc | tratamento de cistos epiteliais por injeção intracística de partículas antineoplásicas |
| EP3615004B1 (en) | 2017-06-14 | 2025-02-19 | Crititech, Inc. | Methods for treating lung disorders |
| JP7792750B2 (ja) | 2017-10-03 | 2025-12-26 | クリティテック・インコーポレイテッド | 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達 |
| EP3765035A4 (en) | 2018-03-16 | 2021-10-27 | DFB Soria, LLC | TOPICAL THERAPY FOR THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND COLD CANCER USING TAXANE NANOPARTICLES |
| JP2026505783A (ja) * | 2023-01-31 | 2026-02-18 | 石薬集団中奇制薬技術（石家庄）有限公司 | 腫瘍を治療するためのパクリタキセルカチオンリポソームの使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1254135B (it) | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. |
| DE69329073T2 (de) * | 1992-03-23 | 2001-01-18 | Georgetown University, Washington | In liposomen verkapseltes taxol und verwendungsverfahren |
| DE4430593C2 (de) * | 1994-08-20 | 1999-01-14 | Max Delbrueck Centrum | Verfahren zur Herstellung von Liposomal verkapseltem Taxol |
| US7112338B2 (en) * | 1997-03-12 | 2006-09-26 | The Regents Of The University Of California | Cationic liposome delivery of taxanes to angiogenic blood vessels |
| US5837283A (en) * | 1997-03-12 | 1998-11-17 | The Regents Of The University Of California | Cationic lipid compositions targeting angiogenic endothelial cells |
| US7314637B1 (en) * | 1999-06-29 | 2008-01-01 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| US6146659A (en) | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| HUP0202669A3 (en) * | 1999-09-09 | 2004-06-28 | Univ California | Cationic liposome delivery of taxanes to angiogenic bloos vessels |
| UY27185A1 (es) * | 2001-02-28 | 2002-09-30 | Bristol Myers Squibb Co | Dosificación metronómica de taxanos |
| JP2005534718A (ja) * | 2002-06-26 | 2005-11-17 | メディゲーネ オンコロギー ゲゼルシャフト ミット ベシュレンクテル ハフツング | カチオンキャリヤー系において診断化合物および治療化合物を安定化させる新規方法 |
| ATE444062T1 (de) * | 2002-06-26 | 2009-10-15 | Medigene Ag | Herstellung einer kationisch liposomalen zubereitung, einen lipophilen wirkstoff enthaltend |
-
2004
- 2004-10-15 AU AU2004283464A patent/AU2004283464B8/en not_active Ceased
- 2004-10-15 JP JP2006534713A patent/JP5645340B2/ja not_active Expired - Fee Related
- 2004-10-15 DK DK10180750.1T patent/DK2286794T3/en active
- 2004-10-15 ES ES10180750.1T patent/ES2574231T3/es not_active Expired - Lifetime
- 2004-10-15 CA CA2542217A patent/CA2542217C/en not_active Expired - Lifetime
- 2004-10-15 PL PL10180750.1T patent/PL2286794T3/pl unknown
- 2004-10-15 US US10/575,779 patent/US20080063699A1/en not_active Abandoned
- 2004-10-15 PT PT101807501T patent/PT2286794T/pt unknown
- 2004-10-15 EP EP10180750.1A patent/EP2286794B8/en not_active Expired - Lifetime
- 2004-10-15 WO PCT/EP2004/011655 patent/WO2005039533A1/en not_active Ceased
- 2004-10-15 EP EP04790494.1A patent/EP1673069B1/en not_active Expired - Lifetime
- 2004-10-15 HU HUE10180750A patent/HUE028648T2/en unknown
-
2012
- 2012-07-17 JP JP2012159071A patent/JP2012229255A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004283464A1 (en) | 2005-05-06 |
| JP2007508353A (ja) | 2007-04-05 |
| EP2286794B8 (en) | 2016-06-01 |
| AU2004283464B8 (en) | 2011-04-14 |
| PL2286794T3 (pl) | 2016-10-31 |
| ES2574231T3 (es) | 2016-06-16 |
| EP2286794B1 (en) | 2016-03-30 |
| EP2286794A1 (en) | 2011-02-23 |
| AU2004283464B2 (en) | 2011-03-17 |
| CA2542217A1 (en) | 2005-05-06 |
| WO2005039533A1 (en) | 2005-05-06 |
| EP1673069B1 (en) | 2016-10-12 |
| CA2542217C (en) | 2018-03-27 |
| JP2012229255A (ja) | 2012-11-22 |
| EP1673069A1 (en) | 2006-06-28 |
| US20080063699A1 (en) | 2008-03-13 |
| JP5645340B2 (ja) | 2014-12-24 |
| DK2286794T3 (en) | 2016-07-25 |
| HUE028648T2 (en) | 2016-12-28 |
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