PE20191653A1 - Metodos para tratar carcinomas uroteliales del tracto superior - Google Patents
Metodos para tratar carcinomas uroteliales del tracto superiorInfo
- Publication number
- PE20191653A1 PE20191653A1 PE2019000993A PE2019000993A PE20191653A1 PE 20191653 A1 PE20191653 A1 PE 20191653A1 PE 2019000993 A PE2019000993 A PE 2019000993A PE 2019000993 A PE2019000993 A PE 2019000993A PE 20191653 A1 PE20191653 A1 PE 20191653A1
- Authority
- PE
- Peru
- Prior art keywords
- ureter
- utuc
- chemotherapeutic agent
- methods
- catheter
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1078—Urinary tract
- A61M2210/1089—Urethra
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Referido a un metodo para administrar de manera local un agente quimioterapeutico a un carcinoma urotelial de tracto superior (UTUC), que comprende: (a) colocar un cateter con balon que tiene un canal de trabajo, a traves de acceso ureteral retrogrado o anterogrado en el ureter y/o pelvis renal; (b) inflar el balon del cateter de mod que el ureter quede temporalmente obstruido; (c) instilar una formulacion liposomal liquida que comprende un agente quimioterapeutico dentro del canal de trabajo del cateter; y (d) permitir que la formulacion liposomal instilada permanezca en el ureter y/o pelvis renal durante un tiempo suficiente para permitir que al menos una parte de la formulacion liposomal se adhiera a la pared urotelial. En donde el agente quimioterapeutico es taxano o cisplatino. Y se usa en terapia adyuvante con respecto a otros metodos para tratar UTUC, tales como extirpacion o ablacion ureteroscopica del tumor UTUC.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662421055P | 2016-11-11 | 2016-11-11 | |
PCT/US2017/061047 WO2018089759A1 (en) | 2016-11-11 | 2017-11-10 | Methods of treating upper tract urothelial carcinomas |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20191653A1 true PE20191653A1 (es) | 2019-11-07 |
Family
ID=62109985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2019000993A PE20191653A1 (es) | 2016-11-11 | 2017-11-10 | Metodos para tratar carcinomas uroteliales del tracto superior |
Country Status (16)
Country | Link |
---|---|
US (1) | US20190343763A1 (es) |
EP (1) | EP3538074B1 (es) |
JP (1) | JP7096553B2 (es) |
KR (1) | KR20190084284A (es) |
CN (1) | CN110167533A (es) |
AU (1) | AU2017358049B2 (es) |
BR (1) | BR112019009616A2 (es) |
CA (1) | CA3043620A1 (es) |
CL (1) | CL2019001262A1 (es) |
CO (1) | CO2019005881A2 (es) |
CR (1) | CR20190274A (es) |
EA (1) | EA201991143A1 (es) |
MX (1) | MX2019005185A (es) |
NZ (1) | NZ753214A (es) |
PE (1) | PE20191653A1 (es) |
WO (1) | WO2018089759A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA038653B1 (ru) | 2016-01-07 | 2021-09-29 | Вестерн Юниверсити Оф Хелт Сайенсиз | Составы для лечения рака мочевого пузыря |
GB201900389D0 (en) | 2019-01-11 | 2019-02-27 | Queens Univ Of Belfast | Solvent and water-free lipid-based nanoparticles and their methods of manufacture |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6759058B1 (en) | 2001-04-25 | 2004-07-06 | Western Center For Drug Development College Of Pharmacy Western University Of Health Sciences | Enteric-coated proliposomal formulations for poorly water soluble drugs |
CN1589149A (zh) * | 2001-09-24 | 2005-03-02 | 托斯克公司 | 减低毒性的顺铂制剂及其使用方法 |
EP2286794B8 (en) * | 2003-10-15 | 2016-06-01 | SynCore Biotechnology CO., LTD | Use of cationic liposomes comprising paclitaxel |
US20090171241A1 (en) | 2006-03-03 | 2009-07-02 | Garcia Maurice M | System and method for urinary tract cell collection, diagnosis, and chemotherapy |
EP2090305A4 (en) * | 2006-12-08 | 2012-12-26 | Katayama Chemical Ind Co Ltd | LIPOSOME ENCAPSULATING HIGH-CONCENTRATION <O> AMINE </ O> COMPLEX, AND PROCESS FOR PRODUCING THE SAME |
CA2681302C (en) | 2007-03-19 | 2013-07-23 | Dhiraj Khattar | Proliposomal and liposomal compositions of poorly water-soluble compounds |
CN101322689B (zh) * | 2007-06-11 | 2012-10-24 | 江苏先声药物研究有限公司 | 一种多西他赛长循环脂质体及其冻干粉针的制备方法 |
CA2872779A1 (en) * | 2012-05-09 | 2013-11-14 | Western University Of Health Sciences | Proliposomal testosterone formulations |
US20140172118A1 (en) | 2012-12-19 | 2014-06-19 | Cook Medical Technologies Llc | Bioactive Compositions, Bioactive Eluting Devices and Methods of Use Thereof |
US20160175559A1 (en) * | 2014-12-23 | 2016-06-23 | Cook Medical Technologies Llc | Medical Devices for Delivery and Retention of Bioactive Agents |
US20160250177A1 (en) * | 2015-02-17 | 2016-09-01 | Mallinckrodt Llc | Modified docetaxel liposome formulations and uses thereof |
WO2016151595A1 (en) * | 2015-03-26 | 2016-09-29 | Vensica Medical Ltd. | Ultrasonic urinary bladder drug delivery |
EP3285820A4 (en) * | 2015-04-24 | 2018-12-12 | Urotronic, Inc. | Drug coated balloon catheters for nonvascular strictures |
JP6249987B2 (ja) | 2015-05-13 | 2017-12-20 | ルトニックス,インコーポレーテッド | 医療用具のための薬物放出コーティング |
EA038653B1 (ru) | 2016-01-07 | 2021-09-29 | Вестерн Юниверсити Оф Хелт Сайенсиз | Составы для лечения рака мочевого пузыря |
-
2017
- 2017-11-10 CA CA3043620A patent/CA3043620A1/en active Pending
- 2017-11-10 CR CR20190274A patent/CR20190274A/es unknown
- 2017-11-10 PE PE2019000993A patent/PE20191653A1/es unknown
- 2017-11-10 WO PCT/US2017/061047 patent/WO2018089759A1/en unknown
- 2017-11-10 NZ NZ753214A patent/NZ753214A/en active IP Right Revival
- 2017-11-10 EA EA201991143A patent/EA201991143A1/ru unknown
- 2017-11-10 CN CN201780080507.4A patent/CN110167533A/zh active Pending
- 2017-11-10 JP JP2019524304A patent/JP7096553B2/ja active Active
- 2017-11-10 KR KR1020197016696A patent/KR20190084284A/ko not_active Application Discontinuation
- 2017-11-10 AU AU2017358049A patent/AU2017358049B2/en not_active Expired - Fee Related
- 2017-11-10 EP EP17869130.9A patent/EP3538074B1/en active Active
- 2017-11-10 US US16/348,801 patent/US20190343763A1/en not_active Abandoned
- 2017-11-10 MX MX2019005185A patent/MX2019005185A/es unknown
- 2017-11-10 BR BR112019009616A patent/BR112019009616A2/pt active Search and Examination
-
2019
- 2019-05-08 CL CL2019001262A patent/CL2019001262A1/es unknown
- 2019-06-05 CO CONC2019/0005881A patent/CO2019005881A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN110167533A (zh) | 2019-08-23 |
EA201991143A1 (ru) | 2019-10-31 |
AU2017358049B2 (en) | 2023-11-09 |
AU2017358049A1 (en) | 2019-05-30 |
CL2019001262A1 (es) | 2019-07-26 |
EP3538074B1 (en) | 2023-07-26 |
BR112019009616A2 (pt) | 2019-08-13 |
CO2019005881A2 (es) | 2019-08-30 |
JP7096553B2 (ja) | 2022-07-06 |
EP3538074A4 (en) | 2020-06-24 |
EP3538074A1 (en) | 2019-09-18 |
NZ753214A (en) | 2022-02-25 |
CA3043620A1 (en) | 2018-05-17 |
MX2019005185A (es) | 2019-07-01 |
WO2018089759A1 (en) | 2018-05-17 |
CR20190274A (es) | 2019-07-29 |
KR20190084284A (ko) | 2019-07-16 |
JP2019534305A (ja) | 2019-11-28 |
US20190343763A1 (en) | 2019-11-14 |
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