PT2232269E - Métodos e biomarcadores para diagnóstico e monitorização de distúrbios psicóticos - Google Patents

Métodos e biomarcadores para diagnóstico e monitorização de distúrbios psicóticos Download PDF

Info

Publication number
PT2232269E
PT2232269E PT88623921T PT08862392T PT2232269E PT 2232269 E PT2232269 E PT 2232269E PT 88623921 T PT88623921 T PT 88623921T PT 08862392 T PT08862392 T PT 08862392T PT 2232269 E PT2232269 E PT 2232269E
Authority
PT
Portugal
Prior art keywords
biomarkers
diagnosing
methods
psychotic disorders
monitoring
Prior art date
Application number
PT88623921T
Other languages
English (en)
Inventor
Sabine Bahn
Yishai Levin
Lan Wang
Emanuel Schwarz
George Mcallister
Original Assignee
Psynova Neurotech Ltd
Cambridge Entpr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psynova Neurotech Ltd, Cambridge Entpr Ltd filed Critical Psynova Neurotech Ltd
Publication of PT2232269E publication Critical patent/PT2232269E/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46NMR spectroscopy
    • G01R33/465NMR spectroscopy applied to biological material, e.g. in vitro testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/302Schizophrenia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Neurology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
PT88623921T 2007-12-19 2008-12-18 Métodos e biomarcadores para diagnóstico e monitorização de distúrbios psicóticos PT2232269E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0724735.6A GB0724735D0 (en) 2007-12-19 2007-12-19 Methods and biomarkers for diagnosing and monitoring psychotic disorders

Publications (1)

Publication Number Publication Date
PT2232269E true PT2232269E (pt) 2014-02-17

Family

ID=40289177

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88623921T PT2232269E (pt) 2007-12-19 2008-12-18 Métodos e biomarcadores para diagnóstico e monitorização de distúrbios psicóticos

Country Status (11)

Country Link
US (1) US20110165554A1 (pt)
EP (2) EP2232269B1 (pt)
JP (1) JP2011506995A (pt)
CN (1) CN101903777A (pt)
AU (1) AU2008337283A1 (pt)
CA (1) CA2706370A1 (pt)
DK (1) DK2232269T3 (pt)
ES (1) ES2445591T3 (pt)
GB (1) GB0724735D0 (pt)
PT (1) PT2232269E (pt)
WO (1) WO2009077763A1 (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8355927B2 (en) 2010-11-05 2013-01-15 Genomind, Llc Neuropsychiatric test reports
GB0915736D0 (en) 2009-09-09 2009-10-07 Cambridge Entpr Ltd Biomarkers
GB0922240D0 (en) * 2009-12-21 2010-02-03 Cambridge Entpr Ltd Biomarkers
GB0922236D0 (en) * 2009-12-21 2010-02-03 Cambridge Entpr Ltd Biomarkers
GB201001419D0 (en) * 2010-01-29 2010-03-17 Cambridge Entpr Ltd Biomarkers
GB201002627D0 (en) 2010-02-16 2010-03-31 Loxbridge Res Llp Aptamer based analyte detection method
DE102010018561B4 (de) 2010-04-28 2012-04-12 Carsten Korth Quantitative Marker zur Bestimmung des mentalen Status eines Probanden
GB201008340D0 (en) * 2010-05-19 2010-07-07 Cambridge Entpr Ltd Biomarkers
JP5876673B2 (ja) * 2010-06-09 2016-03-02 国立大学法人富山大学 精神障害の診断方法および診断薬キット
GB201010316D0 (en) * 2010-06-21 2010-08-04 Cambridge Entpr Ltd Biomarkers
GB201021502D0 (en) * 2010-12-20 2011-02-02 Cambridge Entpr Ltd Biomarkers
US20140200150A1 (en) 2010-12-20 2014-07-17 Cambridge Enterprise Limited Biomarkers
CN102621310B (zh) * 2011-01-28 2014-07-02 上海科新生物技术股份有限公司 胶体金层析法抗u1-rnp抗体检测试纸及其制备方法
WO2012106524A2 (en) * 2011-02-02 2012-08-09 Genomind, Llc Diagnosis and treatment of the prodromal schizophrenic state
KR20120091933A (ko) * 2011-02-10 2012-08-20 건국대학교 산학협력단 뇌졸중 치료 타겟으로서 프로네이나아제-3
EP2688911B1 (en) 2011-03-24 2017-08-02 OPKO Pharmaceuticals, LLC Biomarker discovery in complex biological fluid using bead or particle based libraries
WO2012149607A1 (en) * 2011-05-03 2012-11-08 Commonwealth Scientific And Industrial Research Organisation Method for detection of a neurological disease
JP5814800B2 (ja) * 2011-12-28 2015-11-17 株式会社Lsiメディエンス 神経変性疾患の検出方法
GB201210565D0 (en) 2012-06-14 2012-08-01 Cambridge Entpr Ltd Biomarkers
JP5920827B2 (ja) * 2012-06-21 2016-05-18 国立研究開発法人農業・食品産業技術総合研究機構 病害抵抗性品種系統の識別方法
WO2014144605A1 (en) * 2013-03-15 2014-09-18 Myriad Genetics, Inc. Biomarkers for major depressive disorder
US20140287948A1 (en) * 2013-03-15 2014-09-25 Sera Prognostics, Inc. Biomarkers and methods for predicting preterm birth
CN104062432B (zh) * 2013-03-22 2016-01-20 中山大学 ang2在制备ECTC血管类型肝癌诊断试剂及治疗药物中的应用
JP6205175B2 (ja) 2013-05-16 2017-10-04 株式会社Resvo 精神・神経疾患バイオマーカー
CN103512972A (zh) * 2013-07-29 2014-01-15 上海交通大学 精神分裂症的生物标志物及其使用方法和应用
GB201321474D0 (en) * 2013-12-05 2014-01-22 Cambridge Entpr Ltd Novel biomarkers
GB201404189D0 (en) 2014-03-10 2014-04-23 Cambridge Entpr Ltd Novel biomarkers
JPWO2015174544A1 (ja) * 2014-05-16 2017-04-20 国立研究開発法人国立精神・神経医療研究センター 精神疾患判定マーカー
US9952232B2 (en) * 2014-09-11 2018-04-24 Liposcience, Inc. Cardiovascular risk evaluations using a risk parameter that includes an HDL and inflammatory biomarker interaction parameter
JP2017530356A (ja) 2014-09-26 2017-10-12 ソマロジック, インコーポレイテッドSomaLogic, Inc. 心血管系のリスクイベントの予測及びその使用
JP6840391B2 (ja) 2015-06-19 2021-03-10 セラ プログノスティックス, インコーポレイテッド 早産を予測するためのバイオマーカーの対
CN105506074B (zh) * 2016-03-01 2019-02-15 张理义 一种用于精神分裂症诊断的lncRNA标志物及试剂盒
BR112019010324A2 (pt) 2016-11-22 2019-08-27 Janssen Pharmaceutica Nv métodos para identificar pacientes com esquizofrenia em risco de recidiva
CN107345970B (zh) * 2017-07-20 2019-06-07 首都医科大学附属北京安定医院 一种可用于首发精神分裂症诊断的外周血生物标志物
CA3073192A1 (en) 2017-08-18 2019-02-21 Sera Prognostics, Inc Pregnancy clock proteins for predicting due date and time to birth
CN109868311B (zh) * 2017-12-01 2023-10-20 上海市精神卫生中心 Mif及其预测二代抗精神病药物诱导的代谢不良反应的应用
CN109868312B (zh) * 2017-12-05 2023-07-28 上海市精神卫生中心 IL-1ra与奥氮平诱导的代谢不良反应
CN108931653A (zh) * 2018-08-31 2018-12-04 广州华澳生物科技有限公司 一种α1- 抗胰蛋白酶免疫层析检测试剂卡及其制备方法
CN109728098B (zh) * 2019-01-03 2022-05-17 合肥鑫晟光电科技有限公司 薄膜晶体管、传感器、检测方法、检测装置及检测系统
CN109738495B (zh) * 2019-01-22 2021-07-13 重庆医科大学 基于铈金属有机框架@金纳米复合物和金铂钌纳米复合材料的三金属信号放大适配体传感器用于凝血酶敏感蛋白-1检测
CN115112778B (zh) * 2021-03-19 2023-08-04 复旦大学 一种疾病蛋白质生物标志物鉴定方法
CN118251415A (zh) * 2021-10-29 2024-06-25 清华大学 用于治疗或诊断精神分裂症的方法和产品
CN117451995A (zh) * 2021-12-06 2024-01-26 上海市精神卫生中心(上海市心理咨询培训中心) 用于预测应激后精神心理症状发生的免疫检测试剂盒及应用
KR20240060943A (ko) * 2022-10-31 2024-05-08 주식회사 엑소퍼트 엑소좀 sers 신호를 이용한 인공지능 기반의 정신질환 진단 시스템 및 그 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429947A (en) * 1992-06-17 1995-07-04 Merril; Carl R. Diagnosing Alzheimer's disease and schizophrenia
WO2002040668A2 (de) * 2000-11-15 2002-05-23 Apoxis Sa Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen
JP2004135667A (ja) * 2002-09-27 2004-05-13 Japan Science & Technology Agency 血液を用いた統合失調症の診断方法
US20050209181A1 (en) * 2003-11-05 2005-09-22 Huda Akil Compositions and methods for diagnosing and treating mental disorders
ES2255426B1 (es) 2004-10-19 2007-08-16 Gp Pharm, S.A. Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa).
AU2006303026A1 (en) 2005-10-18 2007-04-26 Psynova Neurotech Limited Methods and biomarkers for diagnosing and monitoring psychotic disorders such as schizophrenia
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
GB0701626D0 (en) 2007-01-22 2007-03-07 Cambridge Entpr Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders

Also Published As

Publication number Publication date
EP2232269B1 (en) 2013-11-20
ES2445591T3 (es) 2014-03-04
JP2011506995A (ja) 2011-03-03
WO2009077763A1 (en) 2009-06-25
CA2706370A1 (en) 2009-06-25
EP2708899A2 (en) 2014-03-19
GB0724735D0 (en) 2008-01-30
CN101903777A (zh) 2010-12-01
DK2232269T3 (da) 2014-02-17
EP2708899A3 (en) 2014-05-28
EP2232269A1 (en) 2010-09-29
AU2008337283A1 (en) 2009-06-25
US20110165554A1 (en) 2011-07-07

Similar Documents

Publication Publication Date Title
GB0724735D0 (en) Methods and biomarkers for diagnosing and monitoring psychotic disorders
GB0701626D0 (en) Methods and biomarkers for diagnosing and monitoring psychotic disorders
EP2272044A4 (en) INFLAMMATION BIOMARKERS FOR MONITORING DEPRESSION DISORDERS
EP2329260A4 (en) DIAGNOSIS AND MONITORING OF DEPRESSIVE DISORDERS BASED ON A PLURALITY OF BIOMARKER PANELS
IL219210A0 (en) Biomarkers and methods for measuring and monitoring inflammatory disease activity
GB2450351B (en) Monitoring an Immunoassay
IL195054A0 (en) Methods and apparatus for identifying disease status using biomarkers
HK1154052A1 (en) Kits for diagnosing prostate conditions
EP2104639A4 (en) CONDITION MONITORING PROCEDURE
HRP20150181T1 (hr) Cd73 kao biomarker za praä†enje razvoja bolesti i procjenu uäśinkovitosti lijeäśenja
EP2501284A4 (en) METHOD FOR DIAGNOSING ADHD AND ASSOCIATED BEHAVIORAL DISORDERS
GB0521098D0 (en) Methods for diagnosing and monitoring psychotic disorders
GB0610632D0 (en) Monitoring apparatus
EP2021313A4 (en) BIOMARKERS AND METHODS FOR DIAGNOSING MULTIPLE SCLEROSIS
EP1972046A4 (en) MONITOR
TWI351185B (en) Methods for interference measurement and prediction
HK1113428A1 (en) Monitoring apparatus
EP2326952A4 (en) BIOMARKERS, KITS AND METHODS FOR DIAGNOSING, MONITORING AND / OR STADIFYING ALZHEIMER'S DISEASE
GB0722068D0 (en) Predictive test
PL2117094T3 (pl) Układ monitorujący i sposób testowania układu
GB0704515D0 (en) Diagnosing psychotic disorders
GB0720548D0 (en) Diagnosing psychotic disorders
GB0704512D0 (en) Diagnosing psychotic disorders
GB0704513D0 (en) Diagnosing psychotic disorders
TWI349772B (en) Testing method