PT2190978T - Um método para identificação, expansão, e remoção de células estaminais adultas e células estaminais cancerígenas - Google Patents
Um método para identificação, expansão, e remoção de células estaminais adultas e células estaminais cancerígenasInfo
- Publication number
- PT2190978T PT2190978T PT87938353T PT08793835T PT2190978T PT 2190978 T PT2190978 T PT 2190978T PT 87938353 T PT87938353 T PT 87938353T PT 08793835 T PT08793835 T PT 08793835T PT 2190978 T PT2190978 T PT 2190978T
- Authority
- PT
- Portugal
- Prior art keywords
- stem cells
- expanding
- identifying
- cancer stem
- removing adult
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
- C12N5/068—Stem cells; Progenitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07114192A EP2022848A1 (en) | 2007-08-10 | 2007-08-10 | A method for identifying, expanding, and removing adult stem cells and cancer stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2190978T true PT2190978T (pt) | 2017-01-31 |
Family
ID=38611770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87938353T PT2190978T (pt) | 2007-08-10 | 2008-08-08 | Um método para identificação, expansão, e remoção de células estaminais adultas e células estaminais cancerígenas |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8906631B2 (pt) |
| EP (3) | EP2022848A1 (pt) |
| CN (2) | CN101868534B (pt) |
| AU (1) | AU2008287605B2 (pt) |
| CA (1) | CA2696047C (pt) |
| DK (1) | DK2190978T3 (pt) |
| ES (1) | ES2617304T3 (pt) |
| HR (1) | HRP20170326T1 (pt) |
| HU (1) | HUE032118T2 (pt) |
| PL (1) | PL2190978T3 (pt) |
| PT (1) | PT2190978T (pt) |
| WO (1) | WO2009022907A2 (pt) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2022848A1 (en) | 2007-08-10 | 2009-02-11 | Hubrecht Institut | A method for identifying, expanding, and removing adult stem cells and cancer stem cells |
| CA2705509A1 (en) | 2007-11-14 | 2009-05-22 | Forerunner Pharma Research Co., Ltd. | Diagnosis and treatment of cancer using anti-gpr49 antibody |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| GB201111244D0 (en) | 2011-06-30 | 2011-08-17 | Konink Nl Akademie Van Wetenschappen Knaw | Culture media for stem cells |
| EP3441458B9 (en) | 2009-02-03 | 2023-08-23 | Koninklijke Nederlandse Akademie van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| WO2011078301A1 (ja) | 2009-12-25 | 2011-06-30 | ファーマロジカルズ・リサーチ プライベート リミテッド | Nog樹立癌細胞株が移植された非ヒト動物モデルを用いた抗癌剤ターゲット探索及びスクリーニング法 |
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| EP2404500A1 (en) | 2010-07-07 | 2012-01-11 | Universite Pierre Et Marie Curie - Paris 6 | A transgenic animal as a model for identifying adult stem cells, and uses thereof |
| US8679474B2 (en) | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| KR20140014064A (ko) | 2010-09-03 | 2014-02-05 | 스템 센트알엑스 인코포레이티드 | 신규한 조절 인자 및 사용 방법 |
| US11124773B2 (en) * | 2010-10-06 | 2021-09-21 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
| NZ611428A (en) | 2010-12-08 | 2015-07-31 | Stemcentrx Inc | Novel modulators and methods of use |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| EP2533045A1 (en) | 2011-06-08 | 2012-12-12 | Université Pierre et Marie Curie Paris 6 | Methods for identifying adult stem cells |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| US10018630B2 (en) | 2011-09-07 | 2018-07-10 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
| WO2013062083A1 (ja) | 2011-10-28 | 2013-05-02 | ファーマロジカルズ・リサーチ プライベート リミテッド | 癌幹細胞特異的分子 |
| EP3045912B1 (en) | 2011-12-19 | 2018-09-19 | UMC Utrecht Holding B.V. | A rapid quantitative assay to measure cftr function in a primary intestinal culture model |
| RU2014138047A (ru) | 2012-02-23 | 2016-04-10 | Орегон Стейт Боард Оф Хайе Эдьюкейшн Он Бехалф Оф Портланд Стейт Юниверсити | Селективное выявление тиолов |
| CA2865415C (en) | 2012-02-24 | 2022-06-21 | Stem Centrx, Inc. | Anti sez6 antibodies and methods of use |
| EP2817338B1 (en) | 2012-02-24 | 2017-07-26 | AbbVie Stemcentrx LLC | Dll3 modulators and methods of use |
| EP2871236A4 (en) * | 2012-07-05 | 2016-03-09 | Nat Cancer Ct | HYBRID FGFR2 GENE |
| JP6495174B2 (ja) | 2012-12-06 | 2019-04-03 | ステムバイオス テクノロジーズ，インコーポレイテッド | Ｌｇｒ５＋体性幹細胞 |
| KR20160037130A (ko) | 2013-02-22 | 2016-04-05 | 스템센트알엑스 인코포레이티드 | 신규한 항체 접합체 및 이의 용도 |
| WO2017160878A1 (en) | 2016-03-14 | 2017-09-21 | Asana Medical, Inc. | Method and composition for treating inflammatory bowel disease |
| US20160045552A1 (en) * | 2013-04-08 | 2016-02-18 | Asana Medical, Inc. | Method and composition for treating inflammatory bowel disease without colectomy |
| JP2015006184A (ja) * | 2013-06-24 | 2015-01-15 | ステムバイオス テクノロジーズ, インコーポレイテッドStembios Technologies, Inc. | 幹細胞及びそのデータを獲得する方法 |
| CN105848671B (zh) | 2013-08-28 | 2019-12-13 | 艾伯维施特姆森特克斯有限责任公司 | 位点特异性抗体缀合方法和组合物 |
| WO2015031541A1 (en) | 2013-08-28 | 2015-03-05 | Stem Centrx, Inc. | Novel sez6 modulators and methods of use |
| EP3041484B1 (en) | 2013-09-06 | 2021-03-03 | Academia Sinica | Human inkt cell activation using glycolipids with altered glycosyl groups |
| EP3046940B1 (en) | 2013-09-17 | 2019-07-03 | F.Hoffmann-La Roche Ag | Methods of using anti-lgr5 antibodies |
| CA2928671A1 (en) | 2013-11-06 | 2015-05-14 | Stemcentrx, Inc. | Novel anti-claudin antibodies and methods of use |
| WO2015089449A2 (en) | 2013-12-12 | 2015-06-18 | Stem Centrx, Inc. | Novel anti-dpep3 antibodies and methods of use |
| JP2017514143A (ja) | 2014-02-21 | 2017-06-01 | アッヴィ・ステムセントルクス・エル・エル・シー | メラノーマに使用するための抗ｄｌｌ３抗体および薬物コンジュゲート |
| KR102440051B1 (ko) | 2014-03-21 | 2022-09-06 | 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 세포외 기질로부터 유래한 최종 멸균된 하이드로겔의 제조 방법 |
| US10597633B2 (en) | 2014-05-16 | 2020-03-24 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture method for organoids |
| KR20170003720A (ko) | 2014-05-27 | 2017-01-09 | 아카데미아 시니카 | 항-ｃｄ20 글리코항체 및 이의 용도 |
| US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
| KR102576850B1 (ko) | 2014-05-27 | 2023-09-11 | 아카데미아 시니카 | 박테로이드 기원의 푸코시다제 및 이의 사용 방법 |
| CA2949834A1 (en) | 2014-05-28 | 2015-12-03 | James Macormack Wells | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| CA2950433A1 (en) | 2014-05-28 | 2015-12-03 | Academia Sinica | Anti-tnf-alpha glycoantibodies and uses thereof |
| SG11201610630RA (en) | 2014-06-25 | 2017-01-27 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Identification of cancer stem cell markers and use of same for diagnosis and treatment |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗ｍｆｉ２抗體及使用方法 |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法 |
| US20160136203A1 (en) * | 2014-11-19 | 2016-05-19 | StemBios Technologies, Inc. | Somatic stem cells for treating bone defects |
| GB201421092D0 (en) | 2014-11-27 | 2015-01-14 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium |
| GB201421094D0 (en) | 2014-11-27 | 2015-01-14 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium |
| CN104360070B (zh) * | 2014-11-28 | 2017-02-22 | 山东新创生物科技有限公司 | 肽基精氨酸脱亚胺酶2在制备肿瘤临床血液诊断试剂中的应用 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| TWI710571B (zh) * | 2015-01-24 | 2020-11-21 | 中央研究院 | 腫瘤標記及其使用方法 |
| CA2981708A1 (en) | 2015-04-03 | 2016-10-06 | Chengkang ZHANG | Ex vivo proliferation of epithelial cells |
| US10100285B2 (en) | 2015-04-03 | 2018-10-16 | Propagenix Inc. | Ex vivo proliferation of epithelial cells |
| CN104862272B (zh) * | 2015-05-29 | 2018-08-10 | 吉林大学 | Y-27632抑制剂在cd44阳性肠干细胞分选中的应用 |
| JP6869231B2 (ja) | 2015-09-11 | 2021-05-12 | プロパジェニクス インコーポレイテッド | ｅｘ ｖｉｖｏでの上皮細胞の増殖 |
| GB201603569D0 (en) | 2016-03-01 | 2016-04-13 | Koninklijke Nederlandse Akademie Van Wetenschappen | Improved differentiation method |
| CA3021098A1 (en) | 2016-04-21 | 2017-10-26 | Abbvie Stemcentrx Llc | Novel anti-bmpr1b antibodies and methods of use |
| CA3016641A1 (en) | 2016-05-05 | 2017-11-09 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| CN109963868B (zh) | 2016-08-22 | 2023-11-14 | 醣基生医股份有限公司 | 抗体、结合片段及使用方法 |
| CN110062764A (zh) | 2016-12-05 | 2019-07-26 | 儿童医院医学中心 | 结肠类器官及其制备和使用方法 |
| US11698366B2 (en) | 2017-03-28 | 2023-07-11 | Keio University | Human tissue stem cell and use thereof |
| US20220095597A1 (en) * | 2019-01-24 | 2022-03-31 | North Carolina State University | Transgenic models for stem cell therapies |
| GB201903573D0 (en) | 2019-03-15 | 2019-05-01 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture method for head and neck organoids |
| GB201906978D0 (en) | 2019-05-17 | 2019-07-03 | Koninklijke Nederlandse Akademie Van Wetenschappen | Improved culture method using integrin agonist |
| WO2021037142A1 (en) * | 2019-08-27 | 2021-03-04 | The Third Hospital Of Hebei Medical University | Multipotent joint progenitor cells, compositions and methods thereof |
| EP3789049A1 (en) | 2019-09-06 | 2021-03-10 | QGel SA | Method for obtaining healthy intestinal organoids |
| US11629385B2 (en) | 2019-11-22 | 2023-04-18 | Tempus Labs, Inc. | Tumor organoid culture compositions, systems, and methods |
| WO2021113821A1 (en) | 2019-12-05 | 2021-06-10 | Tempus Labs, Inc. | Systems and methods for high throughput drug screening |
| WO2021188849A1 (en) * | 2020-03-20 | 2021-09-23 | University Of Houston System | Methods and compositions for treating inflammatory and fibrotic pulmonary disorders |
| US11561178B2 (en) | 2020-04-20 | 2023-01-24 | Tempus Labs, Inc. | Artificial fluorescent image systems and methods |
| WO2022261183A2 (en) * | 2021-06-08 | 2022-12-15 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating and/or identifying an agent for treating intestinal cancers |
| CN113637634A (zh) * | 2021-08-01 | 2021-11-12 | 杭州憶盛医疗科技有限公司 | 一种基于结合化合物的间充质干细胞分离的方法 |
| CN114045336B (zh) * | 2021-09-28 | 2024-01-02 | 中国人民解放军空军军医大学 | Cga基因作为靶点在制备用于诊断和治疗耐药实体瘤药物的应用 |
| GB202204266D0 (en) | 2022-03-25 | 2022-05-11 | Stichting Hubrecht Organoid Tech | Methods for co-culturing genotoxic bacteria and organoids |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| AU2002303437A1 (en) * | 2001-04-20 | 2002-11-05 | Children's Hospital Of Orange County | Isolation of neural stem cells using gangliosides and other surface markers |
| US20040058392A1 (en) | 2002-09-17 | 2004-03-25 | Kylix B.V. | Use of novel stem cell markers for isolation of intestinal stem cells, and use of the intestinal stem cells thus obtained for the preparation of a therapeutical composition |
| US7056685B1 (en) | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
| PT1581812E (pt) | 2003-01-06 | 2008-09-22 | Wyeth Corp | Composições e métodos para diagnóstico e tratamento de cancros do cólon |
| DE10339820A1 (de) * | 2003-08-22 | 2005-03-17 | Hinzmann, Bernd, Dr. | Verwendung von an GPR49 bindenden Substanzen zur Diagnose und Behandlung von Krebs |
| JP2007525491A (ja) * | 2004-01-29 | 2007-09-06 | セルゾーム・アクチェンゲゼルシャフト | Ｇｐｒ４９の使用による、神経変性疾患の治療 |
| CN1925869A (zh) * | 2004-01-29 | 2007-03-07 | 塞尔卓姆股份公司 | 使用gpr49治疗神经变性疾病 |
| CN1940062B (zh) * | 2005-09-28 | 2010-04-28 | 上海市肿瘤研究所 | 一种肝癌干细胞及其分离方法和用途 |
| EP2022848A1 (en) | 2007-08-10 | 2009-02-11 | Hubrecht Institut | A method for identifying, expanding, and removing adult stem cells and cancer stem cells |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| GB201111244D0 (en) | 2011-06-30 | 2011-08-17 | Konink Nl Akademie Van Wetenschappen Knaw | Culture media for stem cells |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| EP3441458B9 (en) | 2009-02-03 | 2023-08-23 | Koninklijke Nederlandse Akademie van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells |
| GB201106395D0 (en) | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| EP3045912B1 (en) | 2011-12-19 | 2018-09-19 | UMC Utrecht Holding B.V. | A rapid quantitative assay to measure cftr function in a primary intestinal culture model |
-
2007
- 2007-08-10 EP EP07114192A patent/EP2022848A1/en not_active Ceased
-
2008
- 2008-08-08 DK DK08793835.3T patent/DK2190978T3/en active
- 2008-08-08 HU HUE08793835A patent/HUE032118T2/en unknown
- 2008-08-08 CN CN200880110833.6A patent/CN101868534B/zh active Active
- 2008-08-08 AU AU2008287605A patent/AU2008287605B2/en active Active
- 2008-08-08 ES ES08793835.3T patent/ES2617304T3/es active Active
- 2008-08-08 PL PL08793835T patent/PL2190978T3/pl unknown
- 2008-08-08 PT PT87938353T patent/PT2190978T/pt unknown
- 2008-08-08 WO PCT/NL2008/050543 patent/WO2009022907A2/en active Application Filing
- 2008-08-08 EP EP16200856.9A patent/EP3190180A3/en not_active Withdrawn
- 2008-08-08 CN CN201410637712.4A patent/CN104483485B/zh active Active
- 2008-08-08 EP EP08793835.3A patent/EP2190978B1/en active Active
- 2008-08-08 CA CA2696047A patent/CA2696047C/en active Active
-
2010
- 2010-05-10 US US12/705,336 patent/US8906631B2/en active Active
-
2014
- 2014-09-23 US US14/494,511 patent/US9833496B2/en active Active
-
2017
- 2017-02-27 HR HRP20170326TT patent/HRP20170326T1/hr unknown
- 2017-11-15 US US15/813,863 patent/US10940180B2/en active Active
-
2021
- 2021-01-28 US US17/161,376 patent/US20210228682A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20170326T1 (hr) | 2017-04-21 |
| EP2190978A2 (en) | 2010-06-02 |
| WO2009022907A2 (en) | 2009-02-19 |
| CA2696047C (en) | 2023-10-03 |
| CN101868534A (zh) | 2010-10-20 |
| EP2190978B1 (en) | 2016-11-30 |
| CA2696047A1 (en) | 2009-02-19 |
| DK2190978T3 (en) | 2017-02-06 |
| ES2617304T3 (es) | 2017-06-16 |
| US9833496B2 (en) | 2017-12-05 |
| CN101868534B (zh) | 2014-12-10 |
| EP3190180A2 (en) | 2017-07-12 |
| PL2190978T3 (pl) | 2017-06-30 |
| US8906631B2 (en) | 2014-12-09 |
| EP2022848A1 (en) | 2009-02-11 |
| EP3190180A3 (en) | 2017-08-09 |
| US20100275280A1 (en) | 2010-10-28 |
| AU2008287605B2 (en) | 2014-07-03 |
| US20150231201A1 (en) | 2015-08-20 |
| WO2009022907A3 (en) | 2009-06-25 |
| US20180221441A1 (en) | 2018-08-09 |
| US20210228682A1 (en) | 2021-07-29 |
| CN104483485A (zh) | 2015-04-01 |
| US20170151308A9 (en) | 2017-06-01 |
| US10940180B2 (en) | 2021-03-09 |
| AU2008287605A1 (en) | 2009-02-19 |
| HUE032118T2 (en) | 2017-08-28 |
| CN104483485B (zh) | 2017-12-12 |
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