PT2170821T - Método para preparar ligantes hidrolisáveis à base de fmoc - Google Patents

Método para preparar ligantes hidrolisáveis à base de fmoc

Info

Publication number
PT2170821T
PT2170821T PT87593398T PT08759339T PT2170821T PT 2170821 T PT2170821 T PT 2170821T PT 87593398 T PT87593398 T PT 87593398T PT 08759339 T PT08759339 T PT 08759339T PT 2170821 T PT2170821 T PT 2170821T
Authority
PT
Portugal
Prior art keywords
hydrolysable linkers
preparing fmoc
based hydrolysable
fmoc
preparing
Prior art date
Application number
PT87593398T
Other languages
English (en)
Inventor
Turecek Peter
Siekmann Juergen
Noe Christian
Stoiber Gerhard
Original Assignee
Baxalta Inc
Baxalta GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc, Baxalta GmbH filed Critical Baxalta Inc
Publication of PT2170821T publication Critical patent/PT2170821T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT87593398T 2007-06-26 2008-06-25 Método para preparar ligantes hidrolisáveis à base de fmoc PT2170821T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93712507P 2007-06-26 2007-06-26

Publications (1)

Publication Number Publication Date
PT2170821T true PT2170821T (pt) 2017-03-07

Family

ID=39810152

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87593398T PT2170821T (pt) 2007-06-26 2008-06-25 Método para preparar ligantes hidrolisáveis à base de fmoc

Country Status (18)

Country Link
US (2) US7714147B2 (pt)
EP (1) EP2170821B1 (pt)
JP (1) JP5612467B2 (pt)
KR (1) KR101667431B1 (pt)
CN (1) CN101754951B (pt)
AR (1) AR067173A1 (pt)
AU (1) AU2008267361B2 (pt)
BR (1) BRPI0813319A2 (pt)
CA (1) CA2690553C (pt)
DK (1) DK2170821T3 (pt)
ES (1) ES2617737T3 (pt)
HK (1) HK1143365A1 (pt)
MX (1) MX2009013678A (pt)
NZ (1) NZ582670A (pt)
PL (1) PL2170821T3 (pt)
PT (1) PT2170821T (pt)
TW (1) TWI434845B (pt)
WO (1) WO2009000523A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933575B (zh) * 2013-01-23 2017-09-29 上海新理念生物医药科技有限公司 一种三齿型连接子及其应用
CN104030962B (zh) * 2014-06-19 2016-03-30 常州吉恩药业有限公司 一种生产芴甲氧羰酰琥珀酰亚胺并联产n,n′-二琥珀酰亚胺基碳酸酯的方法
CN106267225B (zh) 2015-05-29 2020-03-06 上海新理念生物医药科技有限公司 三马来酰亚胺型连接子及其应用
TW201833127A (zh) * 2017-02-27 2018-09-16 日商積水醫療股份有限公司 新穎四環式保護劑
US20200254065A1 (en) * 2019-02-11 2020-08-13 Opko Biologics Ltd. Long-acting glp-2 analogs
CN116253667B (zh) * 2022-12-27 2024-08-30 煤炭科学研究总院有限公司 一种聚集诱导发光材料及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6259259A (ja) * 1985-09-09 1987-03-14 Suntory Ltd エキノカンジン合成中間体及びその製造法
JP2000505473A (ja) * 1996-02-27 2000-05-09 イーライ・リリー・アンド・カンパニー 医薬化合物
US6214966B1 (en) * 1996-09-26 2001-04-10 Shearwater Corporation Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
JP4162840B2 (ja) * 1999-08-20 2008-10-08 セケラ インコーポレイテッド 新規a−500359誘導体
US7122189B2 (en) * 2002-08-13 2006-10-17 Enzon, Inc. Releasable polymeric conjugates based on aliphatic biodegradable linkers
GB0227555D0 (en) * 2002-11-26 2002-12-31 Syngenta Ltd Fungicides
WO2004089280A2 (en) * 2003-04-08 2004-10-21 Yeda Research And Development Co. Ltd. Reversible pegylated drugs
PT2279758E (pt) 2005-06-16 2015-05-27 Nektar Therapeutics Conjugados possuindo uma ligação degradável e reagentes poliméricos úteis na preparação de tais conjugados

Also Published As

Publication number Publication date
EP2170821A1 (en) 2010-04-07
KR20100040301A (ko) 2010-04-19
EP2170821B1 (en) 2016-11-30
AU2008267361A1 (en) 2008-12-31
US20100197940A1 (en) 2010-08-05
AR067173A1 (es) 2009-09-30
WO2009000523A1 (en) 2008-12-31
TWI434845B (zh) 2014-04-21
JP5612467B2 (ja) 2014-10-22
CA2690553C (en) 2016-11-08
HK1143365A1 (en) 2010-12-31
TW200906819A (en) 2009-02-16
US20090005574A1 (en) 2009-01-01
PL2170821T3 (pl) 2017-07-31
AU2008267361B2 (en) 2012-01-19
US8871949B2 (en) 2014-10-28
ES2617737T3 (es) 2017-06-19
US7714147B2 (en) 2010-05-11
DK2170821T3 (en) 2017-03-06
BRPI0813319A2 (pt) 2014-12-23
JP2010531317A (ja) 2010-09-24
KR101667431B1 (ko) 2016-10-18
MX2009013678A (es) 2010-03-08
CN101754951A (zh) 2010-06-23
CA2690553A1 (en) 2008-12-31
NZ582670A (en) 2012-05-25
CN101754951B (zh) 2013-06-12

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