PT2162118T - Microesferas porosas e sua utilização em terapia - Google Patents

Microesferas porosas e sua utilização em terapia

Info

Publication number
PT2162118T
PT2162118T PT87624359T PT08762435T PT2162118T PT 2162118 T PT2162118 T PT 2162118T PT 87624359 T PT87624359 T PT 87624359T PT 08762435 T PT08762435 T PT 08762435T PT 2162118 T PT2162118 T PT 2162118T
Authority
PT
Portugal
Prior art keywords
therapy
porous microspheres
microspheres
porous
Prior art date
Application number
PT87624359T
Other languages
English (en)
Inventor
Michael Day Richard
Blaker Jonny
Original Assignee
Ucl Business Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucl Business Plc filed Critical Ucl Business Plc
Publication of PT2162118T publication Critical patent/PT2162118T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/20—Animals treated with compounds which are neither proteins nor nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00—Foams characterised by the foaming process
    • C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/054—Precipitating the polymer by adding a non-solvent or a different solvent
    • C08J2201/0542—Precipitating the polymer by adding a non-solvent or a different solvent from an organic solvent-based polymer composition
    • C08J2201/0544—Precipitating the polymer by adding a non-solvent or a different solvent from an organic solvent-based polymer composition the non-solvent being aqueous
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]
PT87624359T 2007-06-20 2008-06-20 Microesferas porosas e sua utilização em terapia PT2162118T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0711952.2A GB0711952D0 (en) 2007-06-20 2007-06-20 Microspheres

Publications (1)

Publication Number Publication Date
PT2162118T true PT2162118T (pt) 2017-05-17

Family

ID=38352593

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87624359T PT2162118T (pt) 2007-06-20 2008-06-20 Microesferas porosas e sua utilização em terapia

Country Status (6)

Country Link
US (1) US8765182B2 (pt)
EP (1) EP2162118B1 (pt)
DK (1) DK2162118T3 (pt)
GB (1) GB0711952D0 (pt)
PT (1) PT2162118T (pt)
WO (1) WO2008155558A2 (pt)

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US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
CA2655026C (en) 2006-06-15 2016-08-02 Microvention, Inc. Embolization device constructed from expansible polymer
JP5698537B2 (ja) 2007-12-21 2015-04-08 マイクロベンション インコーポレイテッド 生物医学的使用のためのハイドロゲルフィラメント
US10639396B2 (en) 2015-06-11 2020-05-05 Microvention, Inc. Polymers
US9993252B2 (en) 2009-10-26 2018-06-12 Microvention, Inc. Embolization device constructed from expansile polymer
ES2363397B1 (es) * 2010-01-18 2013-01-24 Sphieric Nanohealth, S.L. Microesferas antisépticas.
WO2012145431A2 (en) 2011-04-18 2012-10-26 Microvention, Inc. Embolic devices
US9011884B2 (en) 2012-04-18 2015-04-21 Microvention, Inc. Embolic devices
US9351993B2 (en) 2012-06-14 2016-05-31 Microvention, Inc. Polymeric treatment compositions
CN102772827B (zh) * 2012-07-13 2014-05-07 华南理工大学 Plga/羟基磷灰石/碳酸钙复合微球及其制备方法
AU2013331439B2 (en) 2012-10-15 2016-05-12 Microvention, Inc. Polymeric treatment compositions
WO2013071316A2 (en) * 2012-12-28 2013-05-16 Starbard Nathan T Porous polymeric particles and methods of making and using them
US20140251927A1 (en) * 2012-12-28 2014-09-11 Nathan T. Starbard Porous Polymeric Particles and Methods of Making and Using Them
ITTO20130284A1 (it) * 2013-04-09 2014-10-10 Fond Istituto Italiano Di Tecnologia Procedimento per la produzione di microparticelle polimeriche sagomate
WO2014209620A1 (en) 2013-06-28 2014-12-31 3M Innovative Properties Company Fibrin-coated wound dressing
GB201322869D0 (en) * 2013-12-23 2014-02-12 Ucl Business Plc Therapeutic agents and delivery with microspheres
GB201405874D0 (en) * 2014-04-01 2014-05-14 Aga Nanotech Ltd A therapeutic agent for use in the treatment of infections
US10124090B2 (en) 2014-04-03 2018-11-13 Terumo Corporation Embolic devices
WO2015167751A1 (en) 2014-04-29 2015-11-05 Microvention, Inc. Polymers
EP3137124B1 (en) 2014-04-29 2019-01-09 Microvention, Inc. Polymers including active agents
US9862807B2 (en) 2014-10-06 2018-01-09 The Regents Of The University Of Michigan Nanofibrous spongy microspheres
WO2018005518A1 (en) * 2016-06-27 2018-01-04 Tamarisk Technologies Group Llc Pharmaceutical preparation for delivery of peptides and proteins
US11684574B2 (en) 2016-06-30 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Artificial cells and delivery devices for use in tissue engineering, and related methods
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
KR20190082197A (ko) 2016-09-11 2019-07-09 쉔카르 엔지니어링 디자인 아트 미소 구체 및 그 제조 방법
GB201622024D0 (en) * 2016-11-14 2017-02-08 Inventage Lab Inc Apparatus and method for large scale production of monodisperse, microsheric and biodegradable polymer-based drug delivery
CN109280209B (zh) * 2017-07-19 2021-02-26 中国科学院化学研究所 一种聚合物多孔微球及由其制备的碳球、超黑材料和应用
AU2018329177B2 (en) * 2017-09-11 2024-04-18 Basf Se Microspheres comprising polydisperse polymer nanospheres and porous metal oxide microspheres
IL272995B2 (en) 2017-09-11 2024-01-01 Harvard College Porous metal oxide microspheres
CN111200976B (zh) 2017-10-09 2023-07-07 微仙美国有限公司 放射性液体栓塞
CN109897205B (zh) * 2017-12-11 2021-10-01 上海中医药大学 一种体积可控plga微球的制备方法
US20210308258A1 (en) * 2018-08-20 2021-10-07 Institute Of Process Engineering, Chinese Academy Of Sciences Microcapsule-based vaccine
GB201914849D0 (en) * 2019-10-14 2019-11-27 Ucl Business Ltd Microsphere-drug combination
GB2592911B (en) 2020-02-28 2023-06-28 Aga Nanotech Ltd A plasma-activatable wound dressing for treatment of infections
US11479494B2 (en) 2020-03-30 2022-10-25 George G. Wicks Porous glass microspheres, composite materials and methods of using same
CN114345252B (zh) * 2021-12-28 2022-09-02 华熙生物科技股份有限公司 一种聚合物微球及其制备方法
CN114767929A (zh) * 2022-03-14 2022-07-22 上海理工大学 一种连通多孔PHBHHx骨填充微球材料及其制备方法
CN115651457B (zh) * 2022-10-25 2023-10-31 东华大学 一种具有三维纳米网络结构的块状体材料及其制备方法
CN116462879A (zh) * 2023-03-15 2023-07-21 上海英拜生物科技有限公司 一种明胶微球载体及其应用

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Also Published As

Publication number Publication date
EP2162118B1 (en) 2017-02-01
DK2162118T3 (en) 2017-03-06
US20100247663A1 (en) 2010-09-30
WO2008155558A3 (en) 2009-10-29
EP2162118A2 (en) 2010-03-17
US8765182B2 (en) 2014-07-01
GB0711952D0 (en) 2007-08-01
WO2008155558A2 (en) 2008-12-24

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