PT2121682E - Derivados de 4-(pirrololpiridinil)-pirimidin-2-il-amina - Google Patents

Derivados de 4-(pirrololpiridinil)-pirimidin-2-il-amina Download PDF

Info

Publication number
PT2121682E
PT2121682E PT87073409T PT08707340T PT2121682E PT 2121682 E PT2121682 E PT 2121682E PT 87073409 T PT87073409 T PT 87073409T PT 08707340 T PT08707340 T PT 08707340T PT 2121682 E PT2121682 E PT 2121682E
Authority
PT
Portugal
Prior art keywords
pyrrolopyridinyl
pyrimidin
ylamine derivatives
ylamine
derivatives
Prior art date
Application number
PT87073409T
Other languages
English (en)
Portuguese (pt)
Inventor
Dieter Dorsch
Christian Sirrenberg
Thomas J J Mueller
Eugen Merkul
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT2121682E publication Critical patent/PT2121682E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT87073409T 2007-02-21 2008-01-28 Derivados de 4-(pirrololpiridinil)-pirimidin-2-il-amina PT2121682E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007008419A DE102007008419A1 (de) 2007-02-21 2007-02-21 4-(Pyrrolopyridinyl)-pyrimidinyl-2-amin-derivate

Publications (1)

Publication Number Publication Date
PT2121682E true PT2121682E (pt) 2013-10-17

Family

ID=39410261

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87073409T PT2121682E (pt) 2007-02-21 2008-01-28 Derivados de 4-(pirrololpiridinil)-pirimidin-2-il-amina

Country Status (18)

Country Link
US (2) US8293891B2 (enExample)
EP (1) EP2121682B1 (enExample)
JP (1) JP5508026B2 (enExample)
KR (1) KR20090110948A (enExample)
CN (1) CN101616918A (enExample)
AR (1) AR065390A1 (enExample)
AU (1) AU2008217297B2 (enExample)
BR (1) BRPI0808167A2 (enExample)
CA (1) CA2678691C (enExample)
DE (1) DE102007008419A1 (enExample)
DK (1) DK2121682T3 (enExample)
EA (1) EA200901100A1 (enExample)
ES (1) ES2427594T3 (enExample)
IL (1) IL200470A (enExample)
MX (1) MX2009008864A (enExample)
PT (1) PT2121682E (enExample)
WO (1) WO2008101587A1 (enExample)
ZA (1) ZA200906539B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2026654A4 (en) * 2006-05-26 2013-07-17 Univ Louisville Res Found MACROPHAGE MIGRATION HEMMFAKTOR ANTAGONISTS AND USE METHOD THEREFOR
US9162987B2 (en) 2009-09-24 2015-10-20 University Of Louisville Research Foundation, Inc. Iodo pyrimidine derivatives useful for the treatment of macrophage migration inhibitory factor (MIF)-implicated diseases and conditions
US9155790B2 (en) 2010-05-20 2015-10-13 University of Lousiville Research Foundation, Inc. Methods and compositions for modulating ocular damage

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747469A (en) 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
GB9904387D0 (en) 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
RU2292904C2 (ru) * 2001-01-09 2007-02-10 Мерк Патент Гмбх Комбинированная терапия, использующая ингибиторы рецептора тирозинкиназы и ингибиторы ангиогенезиса
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
WO2006038001A1 (en) * 2004-10-06 2006-04-13 Celltech R & D Limited Aminopyrimidine derivatives as jnk inhibitors

Also Published As

Publication number Publication date
WO2008101587A1 (de) 2008-08-28
BRPI0808167A2 (pt) 2014-07-08
MX2009008864A (es) 2009-08-28
US8293891B2 (en) 2012-10-23
ES2427594T3 (es) 2013-10-31
JP2010519230A (ja) 2010-06-03
AU2008217297A1 (en) 2008-08-28
DE102007008419A1 (de) 2008-08-28
CA2678691A1 (en) 2008-08-28
US20120264999A1 (en) 2012-10-18
DK2121682T3 (da) 2013-09-08
EP2121682B1 (de) 2013-07-10
IL200470A0 (en) 2010-04-29
JP5508026B2 (ja) 2014-05-28
AR065390A1 (es) 2009-06-03
EA200901100A1 (ru) 2010-02-26
ZA200906539B (en) 2010-06-30
US8557977B2 (en) 2013-10-15
US20110092527A1 (en) 2011-04-21
KR20090110948A (ko) 2009-10-23
EP2121682A1 (de) 2009-11-25
CA2678691C (en) 2015-09-08
IL200470A (en) 2014-02-27
AU2008217297B2 (en) 2013-01-17
CN101616918A (zh) 2009-12-30

Similar Documents

Publication Publication Date Title
MY155719A (en) 2-benzylpyridazinone derivatives as met kinase inhibitors
WO2010000364A8 (de) Pyrrolopyridinyl-pyrimidin-2-yl-amin-derivate
MX2009012708A (es) Derivados de piridazinona.
MX2009013341A (es) Derivados de 6-(pirrolopiridinil)-pirimidinil-2-amina.
MY153727A (en) Pyridazinone derivatives
MX2010003366A (es) Derivados de piperidina y piperazina para el tratamiento de tumores.
MX2009010034A (es) Pirimidodiazepinas sustituidas utiles inhibidores de la plk1.
MX2010007927A (es) Derivados de 4-(pirrolo[2,3-c]piridin-3-il)pirimidin-2-ilamina.
MX2009012709A (es) Derivados de arileter-piridazinona.
MX2009013077A (es) Derivados dde benzoxazolona.
UA104731C2 (ru) Ингибиторы р38 мар-киназ
MX2009008798A (es) Derivados de iminipiridina y sus usos como microbicidas.
MX2010003368A (es) Derivados de imidazol.
IL191832A (en) Pyridiazinone compounds and their use in the preparation of drugs for the treatment of tumors
WO2008017361A3 (de) 2-(heterocyclylbenzyl)-pyridazinonderivate
MX2007008137A (es) Triazoloftalazinas como inhibidores de pde2.
ZA200701137B (en) Triazolophthalazines
MX2010003365A (es) Derivados de tiazol para el tratamiento de cancer.
MX2011011488A (es) Derivados de 3-([1,2,3]triazol-4-il)-pirrolo[2,3-b]piridina.
EA201100035A1 (ru) Производные тиазолилпиперидина
MX2011007165A (es) Derivados de piridazinona.
MY152061A (en) Pyrrolopyrimidinecarboxamides
MX2008002104A (es) Derivados de 1-acildihidropirazol.
IL198465A0 (en) Triazabenzo[e]azulene derivatives for the treatment of tumors
MX2016007810A (es) Derivados de n1-(3,3,3-trifluoro-2-hidroxo-2-metilpropionil)-piper idina como inhibidores de piruvato deshidrogenasa cinasa.