PT2101777E - Composição para tratar uma hipertensão pulmonar - Google Patents
Composição para tratar uma hipertensão pulmonar Download PDFInfo
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- PT2101777E PT2101777E PT78550654T PT07855065T PT2101777E PT 2101777 E PT2101777 E PT 2101777E PT 78550654 T PT78550654 T PT 78550654T PT 07855065 T PT07855065 T PT 07855065T PT 2101777 E PT2101777 E PT 2101777E
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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Landscapes
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- Chemical & Material Sciences (AREA)
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- Cardiology (AREA)
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Applications Claiming Priority (1)
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| US86966706P | 2006-12-12 | 2006-12-12 |
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| PT2101777E true PT2101777E (pt) | 2015-09-18 |
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| PT78550654T PT2101777E (pt) | 2006-12-12 | 2007-12-11 | Composição para tratar uma hipertensão pulmonar |
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| EP (2) | EP2101777B1 (https=) |
| JP (1) | JP2010512414A (https=) |
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| CA (1) | CA2669536C (https=) |
| CY (1) | CY2016017I2 (https=) |
| DK (1) | DK2101777T3 (https=) |
| ES (1) | ES2544724T3 (https=) |
| HK (1) | HK1218393A1 (https=) |
| HU (2) | HUE025355T2 (https=) |
| LU (1) | LU93081I2 (https=) |
| PL (1) | PL2101777T3 (https=) |
| PT (1) | PT2101777E (https=) |
| SI (1) | SI2101777T1 (https=) |
| WO (1) | WO2008073928A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2101777B1 (en) | 2006-12-12 | 2015-05-20 | Gilead Sciences, Inc. | Composition for treating a pulmonary hypertension |
| CN101815534A (zh) * | 2007-07-11 | 2010-08-25 | 莱西肯医药有限公司 | 用于治疗肺动脉高压以及相关疾病和病症的方法和组合物 |
| AU2008282773B8 (en) | 2007-07-31 | 2013-03-07 | Gilead Sciences, Inc. | Metabolites and derivatives of ambrisentan |
| WO2010062640A1 (en) * | 2008-10-28 | 2010-06-03 | Gilead Colorado, Inc. | Methods for treating idiopathic pulmonary fibrosis and associated complications |
| BR112012032766A2 (pt) * | 2010-06-30 | 2019-09-24 | Gilead Sciences Inc | uso de antagonistas do receptor de adenosina a2b para o tratamento da hipertensão pulmonar |
| NZ610012A (en) * | 2010-10-15 | 2015-05-29 | Gilead Sciences Inc | Compositions and methods of treating pulmonary hypertension |
| EP2741777B1 (en) * | 2011-08-12 | 2017-01-18 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| US20130225595A1 (en) * | 2012-02-29 | 2013-08-29 | Gilead Sciences, Inc. | Method for treating pulmonary arterial hypertension in a patient not having idiopathic pulmonary fibrosis |
| US20130224306A1 (en) * | 2012-02-29 | 2013-08-29 | Gilead Sciences, Inc. | Method for treating a pulmonary hypertension condition without companion diagnosis |
| WO2014003678A1 (en) * | 2012-06-28 | 2014-01-03 | Xspray Microparticles Ab | Pharmaceutical compositions comprising ambrisentan and solid dispersion particles containing tadalafil |
| US10518112B2 (en) * | 2014-06-18 | 2019-12-31 | Sonivie Ltd. | Method for treating secondary pulmonary hypertension |
| US10576083B2 (en) * | 2015-08-13 | 2020-03-03 | Cipla (UK) Limited | Method of treating pulmonary arterial hypertension |
| HRP20210694T1 (hr) | 2016-07-15 | 2021-09-17 | Acceleron Pharma, Inc. | Pripravci koji sadrže actriia polipeptide za uporabu za liječenje plućne hipertenzije |
| CA3073948A1 (en) * | 2017-08-30 | 2019-03-07 | Bellerophon Pulse Technologies Llc | Use of inhaled nitric oxide for the improvement of right and/or left ventricular function |
| EP3731913A4 (en) * | 2017-12-28 | 2021-09-01 | Bellerophon Pulse Technologies LLC | USE OF INHALED NITROGEN OXIDE AND OXYGEN TO TREAT PULMONIC HYPERTENSION |
| WO2020225297A1 (en) * | 2019-05-06 | 2020-11-12 | Actelion Pharmaceuticals Ltd | Methods for treating sarcoidosis-associated pulmonary hypertension |
| WO2021126884A1 (en) | 2019-12-16 | 2021-06-24 | Tenax Therapeutics, Inc. | LEVOSIMENDAN FOR TREATING PULMONARY HYPERTENSION WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION (PH-HF-pEF) |
| RU2729033C1 (ru) * | 2020-02-03 | 2020-08-03 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ прогнозирования эффективности длительной специфической терапии у пациентов с идиопатической легочной гипертензией и неоперабельной хронической тромбоэмболической легочной гипертензией |
| EP4142769A4 (en) | 2020-04-28 | 2024-05-15 | Acceleron Pharma Inc. | ACTRII PROTEINS AND USE IN THE TREATMENT OF POSTCAPILLARY PULMONARY HYPERTENSION |
| EP3906928A1 (en) * | 2020-05-06 | 2021-11-10 | Noorik Biopharmaceuticals AG | Treatment of pulmonary complications of coronavirus |
| WO2021219671A1 (en) * | 2020-04-28 | 2021-11-04 | Noorik Biopharmaceuticals Ag | Treatment of pulmonary complications of coronavirus infections |
| CN114324900A (zh) * | 2021-12-03 | 2022-04-12 | 上海市肺科医院 | 一种促卵泡激素的应用 |
| EP4456897A4 (en) | 2021-12-31 | 2025-12-10 | Tenax Therapeutics Inc | ORAL FORMULATIONS OF LEVOSIMENDAN FOR THE TREATMENT OF PULMONARY HYPERTENSION WITH HEART FAILURE AND PRESERVED EJECTION FRACTION |
| KR20260035797A (ko) * | 2023-01-09 | 2026-03-13 | 에스씨파마슈티칼스 인코포레이티드 | 루프 이뇨제를 사용한 치료 방법 |
| EP4684777A1 (en) | 2024-07-24 | 2026-01-28 | Adalvo Limited | A fixed-dose pharmaceutical composition comprising (2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid and (6r,12ar)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino{1',2:1,6]pyrido[3,4-b]indole-1,4-dione |
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| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US4325525A (en) | 1980-11-13 | 1982-04-20 | General Motors Corporation | Mounting member |
| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
| US5250534A (en) | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
| DE4313412A1 (de) | 1993-04-23 | 1994-10-27 | Basf Ag | 3-(Het)aryl-Carbonsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung |
| GB9401090D0 (en) | 1994-01-21 | 1994-03-16 | Glaxo Lab Sa | Chemical compounds |
| DE19533023B4 (de) | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| US6362178B1 (en) | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| US6821975B1 (en) | 1999-08-03 | 2004-11-23 | Lilly Icos Llc | Beta-carboline drug products |
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| US20060205733A1 (en) | 2004-08-26 | 2006-09-14 | Encysive Pharmaceuticals | Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof |
| CN101072564A (zh) | 2004-08-26 | 2007-11-14 | 恩希赛弗制药公司 | 内皮缩血管肽a受体(eta)拮抗剂与磷酸二酯酶5(pde5)抑制剂的联合及其用途 |
| JP2008528604A (ja) | 2005-01-25 | 2008-07-31 | グラクソ グループ リミテッド | 抗菌剤 |
| RS20080484A (sr) * | 2006-04-21 | 2009-07-15 | Pfizer Products Inc., | PIRIDIN[3,4-b] PIRAZINONI |
| EP2101777B1 (en) * | 2006-12-12 | 2015-05-20 | Gilead Sciences, Inc. | Composition for treating a pulmonary hypertension |
| US20080139483A1 (en) * | 2006-12-12 | 2008-06-12 | Gorczynski Richard J | Drug combination for hypertensive disorders |
| AU2008282773B8 (en) | 2007-07-31 | 2013-03-07 | Gilead Sciences, Inc. | Metabolites and derivatives of ambrisentan |
| WO2010062640A1 (en) | 2008-10-28 | 2010-06-03 | Gilead Colorado, Inc. | Methods for treating idiopathic pulmonary fibrosis and associated complications |
| NZ610012A (en) | 2010-10-15 | 2015-05-29 | Gilead Sciences Inc | Compositions and methods of treating pulmonary hypertension |
-
2007
- 2007-12-11 EP EP07855065.4A patent/EP2101777B1/en not_active Revoked
- 2007-12-11 ES ES07855065.4T patent/ES2544724T3/es active Active
- 2007-12-11 DK DK07855065.4T patent/DK2101777T3/en active
- 2007-12-11 AU AU2007333115A patent/AU2007333115B2/en active Active
- 2007-12-11 CA CA2669536A patent/CA2669536C/en active Active
- 2007-12-11 WO PCT/US2007/087058 patent/WO2008073928A1/en not_active Ceased
- 2007-12-11 EP EP15168201.0A patent/EP2952193A1/en not_active Withdrawn
- 2007-12-11 PL PL07855065T patent/PL2101777T3/pl unknown
- 2007-12-11 SI SI200731668T patent/SI2101777T1/sl unknown
- 2007-12-11 US US11/953,955 patent/US20080139593A1/en not_active Abandoned
- 2007-12-11 PT PT78550654T patent/PT2101777E/pt unknown
- 2007-12-11 JP JP2009541511A patent/JP2010512414A/ja not_active Withdrawn
- 2007-12-11 HU HUE07855065A patent/HUE025355T2/en unknown
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2010
- 2010-02-17 US US12/706,818 patent/US20100152217A1/en not_active Abandoned
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2011
- 2011-06-16 US US13/162,137 patent/US8377933B2/en active Active
-
2012
- 2012-12-21 US US13/723,758 patent/US20130116257A1/en not_active Abandoned
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2014
- 2014-02-17 US US14/182,208 patent/US9474752B2/en active Active
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2015
- 2015-04-24 US US14/695,775 patent/US9504685B2/en active Active
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2016
- 2016-05-20 CY CY2016017C patent/CY2016017I2/el unknown
- 2016-05-20 HU HUS1600027C patent/HUS1600027I1/hu unknown
- 2016-05-20 LU LU93081C patent/LU93081I2/fr unknown
- 2016-06-06 HK HK16106422.7A patent/HK1218393A1/en unknown
- 2016-11-23 US US15/360,304 patent/US9993475B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100152217A1 (en) | 2010-06-17 |
| US20140296244A1 (en) | 2014-10-02 |
| US20110245253A1 (en) | 2011-10-06 |
| CY2016017I1 (el) | 2016-10-05 |
| LU93081I2 (fr) | 2016-07-20 |
| DK2101777T3 (en) | 2015-08-17 |
| EP2101777B1 (en) | 2015-05-20 |
| ES2544724T3 (es) | 2015-09-03 |
| EP2101777A1 (en) | 2009-09-23 |
| HUS1600027I1 (hu) | 2016-06-28 |
| JP2010512414A (ja) | 2010-04-22 |
| US20170136016A1 (en) | 2017-05-18 |
| CY2016017I2 (el) | 2016-10-05 |
| AU2007333115A1 (en) | 2008-06-19 |
| SI2101777T1 (sl) | 2015-08-31 |
| US9504685B2 (en) | 2016-11-29 |
| US20130116257A1 (en) | 2013-05-09 |
| AU2007333115B2 (en) | 2013-01-10 |
| US9474752B2 (en) | 2016-10-25 |
| HK1218393A1 (en) | 2017-02-17 |
| US20080139593A1 (en) | 2008-06-12 |
| EP2952193A1 (en) | 2015-12-09 |
| CA2669536A1 (en) | 2008-06-19 |
| PL2101777T3 (pl) | 2015-10-30 |
| CA2669536C (en) | 2016-05-31 |
| WO2008073928A1 (en) | 2008-06-19 |
| US8377933B2 (en) | 2013-02-19 |
| US9993475B2 (en) | 2018-06-12 |
| HUE025355T2 (en) | 2016-02-29 |
| US20150224100A1 (en) | 2015-08-13 |
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