PT2101731T - Endoxifeno para utilização no tratamento de cancro - Google Patents
Endoxifeno para utilização no tratamento de cancroInfo
- Publication number
- PT2101731T PT2101731T PT78715638T PT07871563T PT2101731T PT 2101731 T PT2101731 T PT 2101731T PT 78715638 T PT78715638 T PT 78715638T PT 07871563 T PT07871563 T PT 07871563T PT 2101731 T PT2101731 T PT 2101731T
- Authority
- PT
- Portugal
- Prior art keywords
- endoxifen
- cancer
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86042006P | 2006-11-21 | 2006-11-21 | |
| US86078806P | 2006-11-22 | 2006-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2101731T true PT2101731T (pt) | 2018-04-18 |
Family
ID=39492975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78715638T PT2101731T (pt) | 2006-11-21 | 2007-11-21 | Endoxifeno para utilização no tratamento de cancro |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9333190B2 (ja) |
| EP (1) | EP2101731B1 (ja) |
| JP (1) | JP2010510327A (ja) |
| CA (1) | CA2669913C (ja) |
| DK (1) | DK2101731T3 (ja) |
| ES (1) | ES2665917T3 (ja) |
| HU (1) | HUE037109T2 (ja) |
| IN (1) | IN2014MN00139A (ja) |
| PL (1) | PL2101731T3 (ja) |
| PT (1) | PT2101731T (ja) |
| WO (1) | WO2008070463A2 (ja) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PT2101731T (pt) | 2006-11-21 | 2018-04-18 | Jina Pharmaceuticals Inc | Endoxifeno para utilização no tratamento de cancro |
| PT2373305T (pt) * | 2008-12-11 | 2017-06-14 | Besins Healthcare Lu Sarl | Resumo |
| CA3024230C (en) | 2011-04-28 | 2022-10-18 | Oncopeptides Ab | Lyophilized preparation of cytotoxic dipeptides |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| MX365205B (es) * | 2012-10-26 | 2019-05-27 | Oncopeptides Ab | Preparaciones liofilizadas de melfalán flufenamida. |
| JP2018520182A (ja) * | 2015-07-14 | 2018-07-26 | アトッサ ジェネティックス インク． | 乳房障害を処置するための経乳頭方法及び組成物 |
| DE102015222031A1 (de) | 2015-11-10 | 2017-05-11 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Synthese von (Z)-Endoxifenhydrochlorid |
| US20170304232A1 (en) * | 2016-04-20 | 2017-10-26 | Northwestern University | Endoxifen For Local Transdermal Therapy To The Breast |
| WO2019051416A1 (en) | 2017-09-11 | 2019-03-14 | Atossa Genetics Inc. | METHODS FOR THE MANUFACTURE AND USE OF ENDOXIFEN |
| JP7376105B2 (ja) * | 2017-09-11 | 2023-11-08 | アトッサ・セラピューティクス・インコーポレイテッド | 局所用組成物及び処置方法 |
| MX2022000203A (es) * | 2019-07-03 | 2022-03-22 | Atossa Therapeutics Inc | Composiciones de liberacion sostenida de endoxifeno. |
| BR112022020320A2 (pt) | 2020-04-10 | 2022-12-13 | Jina Pharmaceuticals Inc | Método para manter uma concentração terapeuticamente eficaz de endoxifeno para tratamento de um paciente com distúrbio bipolar i |
| US20220296514A1 (en) * | 2021-03-18 | 2022-09-22 | FormuRx Pharmaceuticals Co., Ltd. | Composition and Method of Preparation for Lipid Formulations Comprising Charged Lipids |
| TW202340135A (zh) | 2022-01-12 | 2023-10-16 | 美商阿托薩醫療公司 | （ｚ）—因多昔芬之組合物及其富集方法 |
| WO2023211939A1 (en) * | 2022-04-26 | 2023-11-02 | Atossa Therapeutics, Inc. | High dose endoxifen formulations and methods of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
| EP1138337A3 (en) * | 1994-08-04 | 2003-03-26 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| JP2001507207A (ja) * | 1996-05-01 | 2001-06-05 | イマアーレクス・フアーマシユーチカル・コーポレーシヨン | 化合物を細胞に送達する方法 |
| US6090407A (en) * | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| DK2076244T3 (en) | 2006-10-10 | 2017-02-27 | Jina Pharmaceuticals Inc | Aqueous systems for the preparation of lipid-based pharmaceutical compounds; compositions, methods and uses thereof |
| WO2008048194A1 (en) | 2006-10-20 | 2008-04-24 | Yesilogluj Aysegul Yildiz | Use of the protein kinase c inhibitor tamoxifen for the treatment of bipolar disorder |
| US9637515B2 (en) | 2006-11-06 | 2017-05-02 | Jina Pharmaceuticals, Inc. | Guggulphospholipid methods and compositions |
| US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PT2101731T (pt) | 2006-11-21 | 2018-04-18 | Jina Pharmaceuticals Inc | Endoxifeno para utilização no tratamento de cancro |
| JP5720881B2 (ja) | 2011-01-31 | 2015-05-20 | 東芝ライテック株式会社 | Ｌｅｄランプ点灯装置および照明装置 |
-
2007
- 2007-11-21 PT PT78715638T patent/PT2101731T/pt unknown
- 2007-11-21 PL PL07871563T patent/PL2101731T3/pl unknown
- 2007-11-21 US US12/515,261 patent/US9333190B2/en active Active
- 2007-11-21 JP JP2009538518A patent/JP2010510327A/ja active Pending
- 2007-11-21 WO PCT/US2007/085443 patent/WO2008070463A2/en active Application Filing
- 2007-11-21 IN IN139MUN2014 patent/IN2014MN00139A/en unknown
- 2007-11-21 EP EP07871563.8A patent/EP2101731B1/en not_active Revoked
- 2007-11-21 HU HUE07871563A patent/HUE037109T2/hu unknown
- 2007-11-21 ES ES07871563.8T patent/ES2665917T3/es active Active
- 2007-11-21 DK DK07871563.8T patent/DK2101731T3/en active
- 2007-11-21 CA CA2669913A patent/CA2669913C/en active Active
-
2016
- 2016-04-27 US US15/139,687 patent/US10376479B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9333190B2 (en) | 2016-05-10 |
| WO2008070463A3 (en) | 2008-11-06 |
| EP2101731A4 (en) | 2011-04-20 |
| EP2101731A2 (en) | 2009-09-23 |
| JP2010510327A (ja) | 2010-04-02 |
| IN2014MN00139A (ja) | 2015-06-19 |
| HUE037109T2 (hu) | 2018-08-28 |
| CA2669913A1 (en) | 2008-06-12 |
| WO2008070463A2 (en) | 2008-06-12 |
| US10376479B2 (en) | 2019-08-13 |
| DK2101731T3 (en) | 2018-04-16 |
| ES2665917T3 (es) | 2018-04-30 |
| CA2669913C (en) | 2012-09-18 |
| US20160346230A1 (en) | 2016-12-01 |
| PL2101731T3 (pl) | 2018-07-31 |
| WO2008070463A9 (en) | 2008-09-18 |
| EP2101731B1 (en) | 2018-01-31 |
| US20100112041A1 (en) | 2010-05-06 |
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