PT2096110E - Derivados de acridano-9-ditiocarboxilato para gerar quimiluminescência com uma peroxidase. - Google Patents
Derivados de acridano-9-ditiocarboxilato para gerar quimiluminescência com uma peroxidase. Download PDFInfo
- Publication number
- PT2096110E PT2096110E PT09002933T PT09002933T PT2096110E PT 2096110 E PT2096110 E PT 2096110E PT 09002933 T PT09002933 T PT 09002933T PT 09002933 T PT09002933 T PT 09002933T PT 2096110 E PT2096110 E PT 2096110E
- Authority
- PT
- Portugal
- Prior art keywords
- peroxidase
- acridane
- dithiocarboxylate
- derivatives
- chemiluminescence
- Prior art date
Links
- 102000003992 Peroxidases Human genes 0.000 title abstract 3
- 108040007629 peroxidase activity proteins Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002978 peroxides Chemical class 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/029,222 US6872828B2 (en) | 2001-12-20 | 2001-12-20 | Compounds for generating chemiluminescence with a peroxidase |
| US10/205,050 US6858733B2 (en) | 2001-12-20 | 2002-07-25 | Compounds for generating chemiluminescence with a peroxidase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2096110E true PT2096110E (pt) | 2011-09-27 |
Family
ID=27787385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT09002933T PT2096110E (pt) | 2001-12-20 | 2002-12-18 | Derivados de acridano-9-ditiocarboxilato para gerar quimiluminescência com uma peroxidase. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6872828B2 (https=) |
| EP (1) | EP2096110B1 (https=) |
| JP (1) | JP4686126B2 (https=) |
| AT (2) | ATE425969T1 (https=) |
| DE (1) | DE60231645D1 (https=) |
| DK (1) | DK2096110T3 (https=) |
| ES (2) | ES2323303T3 (https=) |
| PT (1) | PT2096110E (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7247726B2 (en) * | 2001-02-26 | 2007-07-24 | Lumigen, Inc. | Compounds for generating chemiluminescence with a peroxidase |
| US7560556B2 (en) * | 2001-12-20 | 2009-07-14 | Lumigen, Inc. | Assay methods using chemiluminescent detection of peroxidase |
| US7682839B2 (en) * | 2005-03-14 | 2010-03-23 | Lumigen, Inc. | Methods using novel chemiluminescent labels |
| US20060205094A1 (en) * | 2005-03-14 | 2006-09-14 | Lumigen, Inc. | Methods using novel chemiluminescent labels |
| EP1954763B1 (en) * | 2005-11-28 | 2016-11-16 | Dako Denmark A/S | Cyanine dyes and methods for detecting a target using said dyes |
| KR101243918B1 (ko) * | 2006-01-03 | 2013-03-14 | 삼성디스플레이 주식회사 | 청색 발광 고분자, 그 제조방법 및 이를 채용한 유기 전계발광 소자 |
| US20100240070A1 (en) * | 2007-11-07 | 2010-09-23 | Beckman Coulter, Inc. | Nonseparation Assay Methods Using Peroxide Generating Enzymes |
| CA2865254C (en) * | 2012-03-23 | 2020-10-13 | Surmodics, Inc. | Compositions and methods for in vitro diagnostic tests including sulfonic acid |
| HK1220759A1 (zh) | 2013-03-15 | 2017-05-12 | Hycor Biomedical Llc | 用於进行过敏症和自身免疫性疾病的诊断测定的自动化免疫分析系统 |
| CN114184584B (zh) * | 2021-12-06 | 2024-06-04 | 山东航空学院 | 酶测定试胶束液及海洋天然产物抗氧化活性评价方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68911633T2 (de) | 1988-09-30 | 1994-04-07 | Fujirebio Kk | Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz. |
| EP0422252B1 (en) | 1989-04-28 | 1995-07-26 | Toray Industries, Inc. | Method for detecting a substance using chemiluminescence |
| US5324835A (en) | 1990-03-30 | 1994-06-28 | Biosensor Laboratories Co., Ltd. | Pyridazinoquinoxalinones for use as chemiluminescent agents |
| US5629168A (en) | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
| WO1994002486A1 (en) | 1992-07-20 | 1994-02-03 | Syntex (U.S.A.) Inc. | Novel chemiluminescent compounds and methods of use |
| US5552298A (en) | 1992-10-23 | 1996-09-03 | Lumigen, Inc. | Enzyme-catalyzed chemiluminescence from hydroxyaryl cyclic diacylhydrazide compounds |
| JP3315775B2 (ja) | 1992-12-24 | 2002-08-19 | 日立化成工業株式会社 | 標識物としてパーオキシダーゼを用いる化学発光分析方法 |
| US5512451A (en) | 1993-04-01 | 1996-04-30 | British Technology Group Limited | Enhancement of chemiluminescent reactions |
| US5593845A (en) | 1993-05-17 | 1997-01-14 | Lumigen, Inc. | Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection |
| US5523212A (en) | 1993-05-17 | 1996-06-04 | Lumigen, Inc. | Aryl N-alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection |
| US5491072A (en) | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| AU9102398A (en) * | 1997-09-12 | 1999-04-05 | Lumigen, Inc. | Novel compounds for generating chemiluminescence with a peroxidase |
| US5922558A (en) * | 1997-09-12 | 1999-07-13 | Lumigen, Inc. | Methods and compositions for generating chemiluminescence with a peroxidase |
| US6126870A (en) * | 1997-09-12 | 2000-10-03 | Lumigen, Inc. | Chemiluminescent labeling compounds |
-
2001
- 2001-12-20 US US10/029,222 patent/US6872828B2/en not_active Expired - Lifetime
-
2002
- 2002-07-25 US US10/205,050 patent/US6858733B2/en not_active Expired - Lifetime
- 2002-12-18 ES ES02789841T patent/ES2323303T3/es not_active Expired - Lifetime
- 2002-12-18 AT AT02789841T patent/ATE425969T1/de not_active IP Right Cessation
- 2002-12-18 AT AT09002933T patent/ATE513814T1/de active
- 2002-12-18 DK DK09002933.1T patent/DK2096110T3/da active
- 2002-12-18 ES ES09002933T patent/ES2368509T3/es not_active Expired - Lifetime
- 2002-12-18 JP JP2003554650A patent/JP4686126B2/ja not_active Expired - Lifetime
- 2002-12-18 DE DE60231645T patent/DE60231645D1/de not_active Expired - Lifetime
- 2002-12-18 EP EP09002933A patent/EP2096110B1/en not_active Expired - Lifetime
- 2002-12-18 PT PT09002933T patent/PT2096110E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE513814T1 (de) | 2011-07-15 |
| JP2005514396A (ja) | 2005-05-19 |
| EP2096110B1 (en) | 2011-06-22 |
| DE60231645D1 (de) | 2009-04-30 |
| US20030170771A1 (en) | 2003-09-11 |
| JP4686126B2 (ja) | 2011-05-18 |
| US6858733B2 (en) | 2005-02-22 |
| EP2096110A1 (en) | 2009-09-02 |
| ES2368509T3 (es) | 2011-11-17 |
| HK1134088A1 (en) | 2010-04-16 |
| ATE425969T1 (de) | 2009-04-15 |
| US20030170762A1 (en) | 2003-09-11 |
| US6872828B2 (en) | 2005-03-29 |
| DK2096110T3 (da) | 2011-10-10 |
| ES2323303T3 (es) | 2009-07-13 |
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