PT2059532E - Moléculas de ligação humanas capazes de neutralizar o vírus da gripe h5n1 e seus usos - Google Patents
Moléculas de ligação humanas capazes de neutralizar o vírus da gripe h5n1 e seus usosInfo
- Publication number
- PT2059532E PT2059532E PT78033107T PT07803310T PT2059532E PT 2059532 E PT2059532 E PT 2059532E PT 78033107 T PT78033107 T PT 78033107T PT 07803310 T PT07803310 T PT 07803310T PT 2059532 E PT2059532 E PT 2059532E
- Authority
- PT
- Portugal
- Prior art keywords
- antibodies
- influenza virus
- binding molecules
- molecules capable
- human binding
- Prior art date
Links
- 241000712461 unidentified influenza virus Species 0.000 title abstract 4
- 230000003472 neutralizing effect Effects 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84293006P | 2006-09-07 | 2006-09-07 | |
| EP06120316 | 2006-09-07 | ||
| EP06120644 | 2006-09-14 | ||
| EP06125107 | 2006-11-30 | ||
| EP07111235 | 2007-06-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2059532E true PT2059532E (pt) | 2013-03-07 |
Family
ID=45468077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78033107T PT2059532E (pt) | 2006-09-07 | 2007-09-06 | Moléculas de ligação humanas capazes de neutralizar o vírus da gripe h5n1 e seus usos |
Country Status (11)
| Country | Link |
|---|---|
| EP (5) | EP2455398B1 (pt) |
| BR (1) | BRPI0716983B8 (pt) |
| DK (5) | DK2450378T3 (pt) |
| ES (1) | ES2402217T3 (pt) |
| MX (1) | MX343198B (pt) |
| MY (1) | MY165458A (pt) |
| NZ (1) | NZ574581A (pt) |
| PT (1) | PT2059532E (pt) |
| RS (1) | RS52688B (pt) |
| SG (2) | SG174773A1 (pt) |
| SI (1) | SI2059532T1 (pt) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110028578A (zh) * | 2019-03-12 | 2019-07-19 | 中国科学院武汉病毒研究所 | 广谱抗h7流感病毒的中和性人源单克隆抗体及其应用 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118126168B (zh) * | 2024-05-10 | 2024-07-19 | 北京纳百生物科技有限公司 | 一种禽流感np蛋白单克隆抗体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4625015A (en) * | 1982-08-23 | 1986-11-25 | Scripps Clinic & Research Foundation | Broad spectrum influenza antisera |
| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
| US5589174A (en) * | 1992-09-17 | 1996-12-31 | Takara Shuzo Co., Ltd. | Anti-human influenza virus antibody |
| US5624949A (en) | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| JP2001512560A (ja) | 1996-10-08 | 2001-08-21 | ユー―ビスイス ベスローテン フェンノートシャップ | 標的に対し特異的な親和性を有するペプチドおよびタンパク質の選択のための方法および手段 |
| PT1161548E (pt) | 1999-04-15 | 2005-06-30 | Crucell Holland Bv | Producao de proteinas recombinantes numa celula humana utilizando sequencias codificando a proteina e1 de adenovirus |
| US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
| EP1402025B1 (en) | 2001-06-15 | 2006-02-01 | Crucell Holland B.V. | Chimaeric phages |
-
2007
- 2007-09-06 EP EP12153015.8A patent/EP2455398B1/en active Active
- 2007-09-06 DK DK12153012.5T patent/DK2450378T3/da active
- 2007-09-06 PT PT78033107T patent/PT2059532E/pt unknown
- 2007-09-06 DK DK12153013.3T patent/DK2450379T3/da active
- 2007-09-06 BR BRPI0716983A patent/BRPI0716983B8/pt not_active IP Right Cessation
- 2007-09-06 MX MX2013010235A patent/MX343198B/es unknown
- 2007-09-06 EP EP12153013.3A patent/EP2450379B1/en active Active
- 2007-09-06 EP EP12153012.5A patent/EP2450378B1/en active Active
- 2007-09-06 DK DK07803310.7T patent/DK2059532T3/da active
- 2007-09-06 EP EP12153016.6A patent/EP2455399B1/en active Active
- 2007-09-06 NZ NZ574581A patent/NZ574581A/en not_active IP Right Cessation
- 2007-09-06 SG SG2011063955A patent/SG174773A1/en unknown
- 2007-09-06 MY MYPI20090915A patent/MY165458A/en unknown
- 2007-09-06 DK DK12153015.8T patent/DK2455398T3/da active
- 2007-09-06 EP EP12153009.1A patent/EP2450376B1/en active Active
- 2007-09-06 SG SG10201607410TA patent/SG10201607410TA/en unknown
- 2007-09-06 ES ES07803310T patent/ES2402217T3/es active Active
- 2007-09-06 DK DK12153016.6T patent/DK2455399T3/da active
- 2007-09-06 RS RS20130086A patent/RS52688B/en unknown
- 2007-09-06 SI SI200731176T patent/SI2059532T1/sl unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110028578A (zh) * | 2019-03-12 | 2019-07-19 | 中国科学院武汉病毒研究所 | 广谱抗h7流感病毒的中和性人源单克隆抗体及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK2455399T3 (da) | 2016-01-25 |
| EP2455399A3 (en) | 2012-05-30 |
| EP2450378A1 (en) | 2012-05-09 |
| RS52688B (en) | 2013-08-30 |
| EP2455399A2 (en) | 2012-05-23 |
| EP2450379B1 (en) | 2015-11-04 |
| BRPI0716983B8 (pt) | 2021-05-25 |
| SI2059532T1 (sl) | 2013-04-30 |
| ES2402217T3 (es) | 2013-04-29 |
| EP2450376A2 (en) | 2012-05-09 |
| DK2455398T3 (da) | 2016-02-08 |
| MX343198B (es) | 2016-10-11 |
| EP2455399B1 (en) | 2015-11-04 |
| BRPI0716983A2 (pt) | 2013-10-15 |
| NZ574581A (en) | 2012-02-24 |
| EP2450376A3 (en) | 2012-08-01 |
| EP2450378B1 (en) | 2015-11-04 |
| EP2450379A1 (en) | 2012-05-09 |
| DK2450379T3 (da) | 2016-02-08 |
| MY165458A (en) | 2018-03-22 |
| DK2059532T3 (da) | 2013-03-18 |
| EP2455398A2 (en) | 2012-05-23 |
| DK2450378T3 (da) | 2016-02-01 |
| SG10201607410TA (en) | 2016-10-28 |
| EP2455398B1 (en) | 2015-11-18 |
| BRPI0716983B1 (pt) | 2019-03-26 |
| SG174773A1 (en) | 2011-10-28 |
| EP2455398A3 (en) | 2012-05-30 |
| EP2450376B1 (en) | 2018-02-28 |
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