PT1843770E - Tadalafil em partículas sólidas com distribuição bimodal do tamanho de partícula - Google Patents
Tadalafil em partículas sólidas com distribuição bimodal do tamanho de partícula Download PDFInfo
- Publication number
- PT1843770E PT1843770E PT06802484T PT06802484T PT1843770E PT 1843770 E PT1843770 E PT 1843770E PT 06802484 T PT06802484 T PT 06802484T PT 06802484 T PT06802484 T PT 06802484T PT 1843770 E PT1843770 E PT 1843770E
- Authority
- PT
- Portugal
- Prior art keywords
- particle size
- size distribution
- solid particulate
- bimodal particle
- particulate tadalafil
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Packages (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Secondary Cells (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71258905P | 2005-08-29 | 2005-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1843770E true PT1843770E (pt) | 2008-08-05 |
Family
ID=37809413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT06802484T PT1843770E (pt) | 2005-08-29 | 2006-08-29 | Tadalafil em partículas sólidas com distribuição bimodal do tamanho de partícula |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070098804A1 (pt) |
| EP (1) | EP1843770B1 (pt) |
| JP (1) | JP2008518041A (pt) |
| KR (1) | KR20070067173A (pt) |
| AT (1) | ATE398451T1 (pt) |
| BR (1) | BRPI0606122A2 (pt) |
| CA (1) | CA2610668A1 (pt) |
| DE (1) | DE602006001510D1 (pt) |
| ES (1) | ES2308750T3 (pt) |
| IL (1) | IL185938A0 (pt) |
| PL (1) | PL1843770T3 (pt) |
| PT (1) | PT1843770E (pt) |
| WO (1) | WO2007027612A2 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7638138B2 (en) | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
| AU2003220808B2 (en) | 2003-03-27 | 2008-08-21 | Bioactis Limited | Powder medicine applicator for nasal cavity |
| CN101668544B (zh) | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
| GB0712316D0 (en) * | 2007-06-26 | 2007-08-01 | Entripneur Ltd | A novel powder and its method of manufacture |
| EP2238979A1 (en) | 2009-04-06 | 2010-10-13 | LEK Pharmaceuticals d.d. | Active pharmaceutical ingredient adsorbed on solid support |
| EP2429495A4 (en) * | 2009-05-15 | 2014-01-22 | Shin Nippon Biomedical Lab Ltd | INTRANASAL PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PHARMACOKINETICS |
| WO2011013003A2 (en) * | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| WO2011030351A2 (en) | 2009-09-03 | 2011-03-17 | Rubicon Research Private Limited | Taste - masked pharmaceutical compositions |
| WO2013109223A1 (en) * | 2012-01-18 | 2013-07-25 | Mahmut Bilgic | Particulate formulations of tadalafil in effervescent form |
| WO2014092661A1 (en) * | 2012-01-18 | 2014-06-19 | Mahmut Bilgic | Particulate formulations of tadalafil in effervescent form |
| US20160136282A1 (en) | 2014-11-18 | 2016-05-19 | Genovate Biotechnology Co., Ltd. | Novel formulation of cilostazol, a quinolinone-derivative used for alleviating the symptom of intermittent claudication in patients with peripheral vascular disease |
| MX2016002581A (es) * | 2016-02-26 | 2017-08-25 | Apotex Tech Inc | Formulaciones farmaceuticas novedosas que comprenden un inhibidor de pde5. |
| CA3018191C (en) * | 2016-03-31 | 2022-01-25 | ImMutriX Therapeutics, Inc. | Method for extracorporeal treatment of preeclampsia and related disorders |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI223598B (en) * | 1998-06-22 | 2004-11-11 | Pfizer Ireland Pharmaceuticals | An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate |
| US6821975B1 (en) * | 1999-08-03 | 2004-11-23 | Lilly Icos Llc | Beta-carboline drug products |
| US6465465B1 (en) * | 2000-03-14 | 2002-10-15 | Arzneimittelwerk Dresden Gmbh | Process for the treatment of erectile dysfunction and product therefor |
| CN1638739A (zh) * | 2000-08-18 | 2005-07-13 | 法玛西雅厄普约翰美国公司 | 治疗成瘾性障碍的化合物 |
| CA2420597C (en) * | 2000-08-31 | 2011-05-17 | Rtp Pharma Inc. | Milled particles |
| AU2002310086B2 (en) * | 2001-05-24 | 2008-09-04 | Alexza Pharmaceuticals, Inc. | Delivery of erectile dysfunction drugs through an inhalation route |
| EA006213B1 (ru) * | 2001-07-31 | 2005-10-27 | Х. Лундбекк А/С | Кристаллическая композиция, содержащая эсциталопрам |
| US20050042177A1 (en) * | 2003-07-23 | 2005-02-24 | Elan Pharma International Ltd. | Novel compositions of sildenafil free base |
-
2006
- 2006-08-29 US US11/512,679 patent/US20070098804A1/en not_active Abandoned
- 2006-08-29 EP EP06802484A patent/EP1843770B1/en not_active Not-in-force
- 2006-08-29 PT PT06802484T patent/PT1843770E/pt unknown
- 2006-08-29 DE DE602006001510T patent/DE602006001510D1/de not_active Expired - Fee Related
- 2006-08-29 WO PCT/US2006/033541 patent/WO2007027612A2/en active Application Filing
- 2006-08-29 KR KR1020077009473A patent/KR20070067173A/ko not_active Application Discontinuation
- 2006-08-29 JP JP2007539382A patent/JP2008518041A/ja active Pending
- 2006-08-29 CA CA002610668A patent/CA2610668A1/en not_active Abandoned
- 2006-08-29 BR BRPI0606122-2A patent/BRPI0606122A2/pt not_active IP Right Cessation
- 2006-08-29 AT AT06802484T patent/ATE398451T1/de not_active IP Right Cessation
- 2006-08-29 ES ES06802484T patent/ES2308750T3/es active Active
- 2006-08-29 PL PL06802484T patent/PL1843770T3/pl unknown
-
2007
- 2007-09-11 IL IL185938A patent/IL185938A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008518041A (ja) | 2008-05-29 |
| WO2007027612A2 (en) | 2007-03-08 |
| CA2610668A1 (en) | 2007-03-08 |
| KR20070067173A (ko) | 2007-06-27 |
| EP1843770A2 (en) | 2007-10-17 |
| EP1843770B1 (en) | 2008-06-18 |
| ES2308750T3 (es) | 2008-12-01 |
| US20070098804A1 (en) | 2007-05-03 |
| ATE398451T1 (de) | 2008-07-15 |
| BRPI0606122A2 (pt) | 2009-06-02 |
| DE602006001510D1 (de) | 2008-07-31 |
| WO2007027612A3 (en) | 2007-08-02 |
| IL185938A0 (en) | 2008-08-07 |
| PL1843770T3 (pl) | 2008-10-31 |
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