PT1631533E - Novo processo para a redução estereosselectiva de betacetoésteres - Google Patents

Novo processo para a redução estereosselectiva de betacetoésteres Download PDF

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Publication number
PT1631533E
PT1631533E PT03816679T PT03816679T PT1631533E PT 1631533 E PT1631533 E PT 1631533E PT 03816679 T PT03816679 T PT 03816679T PT 03816679 T PT03816679 T PT 03816679T PT 1631533 E PT1631533 E PT 1631533E
Authority
PT
Portugal
Prior art keywords
sub
aryl
alkyl
ketoesters
beta
Prior art date
Application number
PT03816679T
Other languages
English (en)
Inventor
Tom Thomas Puthiaparampil
Acharya Poornaprajna
Chandrashek Aswathanarayanappa
Madhavan Sridharan
Sambasivam Ganesh
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of PT1631533E publication Critical patent/PT1631533E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
PT03816679T 2003-04-22 2003-04-22 Novo processo para a redução estereosselectiva de betacetoésteres PT1631533E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000166 WO2004094343A1 (en) 2003-04-22 2003-04-22 NOVEL PROCESS FOR STEREOSELECTIVE REDUCTION OF ß-KETOESTERS

Publications (1)

Publication Number Publication Date
PT1631533E true PT1631533E (pt) 2009-06-04

Family

ID=33307096

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03816679T PT1631533E (pt) 2003-04-22 2003-04-22 Novo processo para a redução estereosselectiva de betacetoésteres

Country Status (10)

Country Link
US (1) US7232920B2 (pt)
EP (1) EP1631533B1 (pt)
AT (1) ATE425132T1 (pt)
AU (1) AU2003231926A1 (pt)
DE (1) DE60326654D1 (pt)
DK (1) DK1631533T3 (pt)
ES (1) ES2323366T3 (pt)
PT (1) PT1631533E (pt)
SI (1) SI1631533T1 (pt)
WO (1) WO2004094343A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
US20070179166A1 (en) * 2003-12-24 2007-08-02 Valerie Niddam-Hildesheim Process for preparation of statins with high syn to anti ratio
CN102827030B (zh) * 2012-09-24 2014-05-07 复旦大学 一种 (3r, 5r)-3, 5-二羟基-6-氰基己酸酯的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645854A (en) * 1985-04-25 1987-02-24 Merck & Co., Inc. Process for preparing HMG-CoA reductase inhibitors with a 3,5-dihydroxypentanoate subunit
DE3638761A1 (de) * 1986-11-13 1988-05-26 Schering Ag Verbesserte ketoreduktion von carbacyclinzwischenprodukten
EP0424929A1 (en) * 1989-10-27 1991-05-02 Takeda Chemical Industries, Ltd. Isoquinolone derivatives, their production and use
FR2670206B1 (fr) * 1990-12-11 1993-01-22 Rhone Poulenc Sante Procede de preparation de derives de l'acide dihydroxy-3,5 pentanouique.
HRP960312B1 (en) * 1995-07-17 2001-10-31 Warner Lambert Co NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS /R-(R*, R*)/-2-(4-FLUOROPHENYL)-"beta", "delta"-DIHYDROXY-5-PHENYL-4-/(PHENYLAMINO)CARBONYL/-1H-PYRROLE -1-HEPTANOIC ACID CALCIUM SALT (2 : 1)
IL127058A (en) * 1996-07-29 2001-07-24 Warner Lambert Co Process for the synthesis of protected esters of acid (S) - 4,3 dehydroxybutyric
US6433213B1 (en) * 1997-12-19 2002-08-13 Warner-Lambert Company Process for the synthesis of 1,3-diols
US6777552B2 (en) 2001-08-16 2004-08-17 Teva Pharmaceutical Industries, Ltd. Processes for preparing calcium salt forms of statins
HUP0303555A3 (en) * 2000-11-16 2005-08-29 Teva Pharma Hydrolysis of [r(r
WO2003004455A2 (en) 2001-07-06 2003-01-16 Teva Pharmaceutical Industries Ltd. Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation
HUP0401145A3 (en) 2001-07-06 2008-08-28 Ciba Sc Holding Ag Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof
IL159719A0 (en) 2001-07-06 2004-06-20 Teva Pharma Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
NZ529913A (en) 2001-08-16 2005-03-24 Teva Pharma Processes for preparing calcium salt forms of statins
WO2003068191A1 (en) 2002-02-14 2003-08-21 Ranbaxy Laboratories Limited Formulations of atorvastatin stabilized with alkali metal additions

Also Published As

Publication number Publication date
ES2323366T3 (es) 2009-07-14
WO2004094343A1 (en) 2004-11-04
EP1631533B1 (en) 2009-03-11
DK1631533T3 (da) 2009-06-02
ATE425132T1 (de) 2009-03-15
DE60326654D1 (de) 2009-04-23
AU2003231926A1 (en) 2004-11-19
EP1631533A1 (en) 2006-03-08
US7232920B2 (en) 2007-06-19
SI1631533T1 (sl) 2009-08-31
US20040259946A1 (en) 2004-12-23
EP1631533A4 (en) 2007-04-25

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