PT1490368E - 2,2-bis(hidroximetil)ciclopropilidenometil-purinas e ¿pirimidinas como agentes antivirais - Google Patents
2,2-bis(hidroximetil)ciclopropilidenometil-purinas e ¿pirimidinas como agentes antivirais Download PDFInfo
- Publication number
- PT1490368E PT1490368E PT03748894T PT03748894T PT1490368E PT 1490368 E PT1490368 E PT 1490368E PT 03748894 T PT03748894 T PT 03748894T PT 03748894 T PT03748894 T PT 03748894T PT 1490368 E PT1490368 E PT 1490368E
- Authority
- PT
- Portugal
- Prior art keywords
- amino
- purines
- purine
- cyclopropylidenemethyl
- pyrimidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36451802P | 2002-03-15 | 2002-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1490368E true PT1490368E (pt) | 2011-10-24 |
Family
ID=29736035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03748894T PT1490368E (pt) | 2002-03-15 | 2003-03-14 | 2,2-bis(hidroximetil)ciclopropilidenometil-purinas e ¿pirimidinas como agentes antivirais |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7393855B2 (pt) |
| EP (1) | EP1490368B1 (pt) |
| AT (1) | ATE518863T1 (pt) |
| AU (1) | AU2003267947B2 (pt) |
| CA (1) | CA2479039C (pt) |
| DK (1) | DK1490368T3 (pt) |
| ES (1) | ES2370114T3 (pt) |
| PT (1) | PT1490368E (pt) |
| WO (1) | WO2003104440A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5420135B2 (ja) | 2002-03-15 | 2014-02-19 | ウエイン・ステイト・ユニバーシテイ | 抗ウイルス薬としての新規２−アミノ−９−［（２−ヒドロキシメチル）シクロプロピリデンメチル］プリン |
| CA2602097A1 (en) * | 2005-03-22 | 2006-09-28 | Daiichi Sankyo Company, Limited | Process for producing carbapenem derivatives having 1-alkylpyrrolidine structure |
| WO2011022712A1 (en) * | 2009-08-21 | 2011-02-24 | Epiphany Biosciences, Inc. | Method of treating infectious mononucleosis with acylic nucleoside derivatives |
| JP7337855B2 (ja) | 2018-03-09 | 2023-09-04 | メディヴィル・アクチエボラーグ | （２，２－ビスヒドロキシメチル）メチレンシクロプロパンヌクレオチドを用いたがんの治療 |
| AU2020236933B2 (en) * | 2019-03-08 | 2023-05-11 | Microbiotix, Inc. | Inhibition of adenovirus with filociclovir |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352991B1 (en) * | 1997-01-08 | 2002-03-05 | Wayne State University | 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents |
| JP5420135B2 (ja) | 2002-03-15 | 2014-02-19 | ウエイン・ステイト・ユニバーシテイ | 抗ウイルス薬としての新規２−アミノ−９−［（２−ヒドロキシメチル）シクロプロピリデンメチル］プリン |
-
2003
- 2003-03-14 PT PT03748894T patent/PT1490368E/pt unknown
- 2003-03-14 CA CA2479039A patent/CA2479039C/en not_active Expired - Lifetime
- 2003-03-14 ES ES03748894T patent/ES2370114T3/es not_active Expired - Lifetime
- 2003-03-14 WO PCT/US2003/007916 patent/WO2003104440A2/en active Application Filing
- 2003-03-14 DK DK03748894.7T patent/DK1490368T3/da active
- 2003-03-14 AU AU2003267947A patent/AU2003267947B2/en not_active Expired
- 2003-03-14 EP EP03748894A patent/EP1490368B1/en not_active Expired - Lifetime
- 2003-03-14 AT AT03748894T patent/ATE518863T1/de active
-
2004
- 2004-09-15 US US10/942,313 patent/US7393855B2/en not_active Expired - Lifetime
-
2008
- 2008-06-16 US US12/139,750 patent/US20090118308A1/en not_active Abandoned
-
2011
- 2011-07-15 US US13/183,722 patent/US8232275B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2479039C (en) | 2011-06-28 |
| US20110275652A1 (en) | 2011-11-10 |
| EP1490368A4 (en) | 2006-07-19 |
| WO2003104440A3 (en) | 2004-04-01 |
| WO2003104440A2 (en) | 2003-12-18 |
| EP1490368B1 (en) | 2011-08-03 |
| US20090118308A1 (en) | 2009-05-07 |
| CA2479039A1 (en) | 2003-12-18 |
| US7393855B2 (en) | 2008-07-01 |
| AU2003267947B2 (en) | 2008-11-13 |
| EP1490368A2 (en) | 2004-12-29 |
| US8232275B2 (en) | 2012-07-31 |
| US20050113393A1 (en) | 2005-05-26 |
| ATE518863T1 (de) | 2011-08-15 |
| AU2003267947A1 (en) | 2003-12-22 |
| ES2370114T3 (es) | 2011-12-12 |
| DK1490368T3 (da) | 2011-10-03 |
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