PT1265888E - Processo para producao de derivados de (s)-nicotina 6-substituida e compost0s intermediarios - Google Patents
Processo para producao de derivados de (s)-nicotina 6-substituida e compost0s intermediariosInfo
- Publication number
- PT1265888E PT1265888E PT01918042T PT01918042T PT1265888E PT 1265888 E PT1265888 E PT 1265888E PT 01918042 T PT01918042 T PT 01918042T PT 01918042 T PT01918042 T PT 01918042T PT 1265888 E PT1265888 E PT 1265888E
- Authority
- PT
- Portugal
- Prior art keywords
- producing
- substituted
- intermediate compounds
- nicotine derivatives
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical class CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000001477 organic nitrogen group Chemical group 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Addiction (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0000933A SE0000933D0 (sv) | 2000-03-21 | 2000-03-21 | Method of producing 6-substituted (S)-nicotine derivatives and intermediate compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1265888E true PT1265888E (pt) | 2004-11-30 |
Family
ID=20278889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01918042T PT1265888E (pt) | 2000-03-21 | 2001-03-21 | Processo para producao de derivados de (s)-nicotina 6-substituida e compost0s intermediarios |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6747156B2 (pt) |
| EP (1) | EP1265888B1 (pt) |
| JP (1) | JP4370073B2 (pt) |
| AT (1) | ATE273295T1 (pt) |
| AU (2) | AU2001244913B2 (pt) |
| CA (1) | CA2402748C (pt) |
| DE (1) | DE60104825T2 (pt) |
| ES (1) | ES2225507T3 (pt) |
| HK (1) | HK1051854B (pt) |
| PT (1) | PT1265888E (pt) |
| SE (1) | SE0000933D0 (pt) |
| TR (1) | TR200402787T4 (pt) |
| WO (1) | WO2001070730A1 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005232129A (ja) * | 2004-02-23 | 2005-09-02 | Air Water Chemical Inc | 芳香族性アセチレン類の製造方法 |
| WO2007001448A2 (en) | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| WO2007070682A2 (en) | 2005-12-15 | 2007-06-21 | Massachusetts Institute Of Technology | System for screening particles |
| WO2008105773A2 (en) | 2006-03-31 | 2008-09-04 | Massachusetts Institute Of Technology | System for targeted delivery of therapeutic agents |
| CA2652280C (en) | 2006-05-15 | 2014-01-28 | Massachusetts Institute Of Technology | Polymers for functional particles |
| WO2007150030A2 (en) * | 2006-06-23 | 2007-12-27 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| WO2008019142A2 (en) * | 2006-08-04 | 2008-02-14 | Massachusetts Institute Of Technology | Oligonucleotide systems for targeted intracellular delivery |
| US20090074828A1 (en) * | 2007-04-04 | 2009-03-19 | Massachusetts Institute Of Technology | Poly(amino acid) targeting moieties |
| MX350501B (es) | 2007-10-12 | 2017-09-07 | Massachusetts Inst Technology | Nanotecnologia de vacuna. |
| US8343498B2 (en) | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| US8343497B2 (en) * | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
| US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| US20110293701A1 (en) | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Multivalent synthetic nanocarrier vaccines |
| TWI455722B (zh) * | 2010-06-04 | 2014-10-11 | Pfizer Vaccines Llc | 用於預防或治療菸鹼成癮之共軛體 |
| AU2014210682B2 (en) * | 2010-06-04 | 2015-10-08 | Pfizer Vaccines Llc | Conjugates for the prevention or treatment of nicotine addiction |
| WO2012061717A1 (en) | 2010-11-05 | 2012-05-10 | Selecta Biosciences, Inc. | Modified nicotinic compounds and related methods |
| CN109172819A (zh) | 2011-07-29 | 2019-01-11 | 西莱克塔生物科技公司 | 产生体液和细胞毒性t淋巴细胞（ctl）免疫应答的合成纳米载体 |
| US9303013B2 (en) | 2014-05-16 | 2016-04-05 | Pfizer Inc. | Conjugates and associated methods of producing them for the prevention or treatment of nicotine addiction |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4155909A (en) * | 1977-06-13 | 1979-05-22 | Philip Morris Incorporated | 2-Alkyl nicotinoids and processes for their production |
| US4465833A (en) * | 1980-10-15 | 1984-08-14 | Hughes Aircraft Company | Process for preparing ethynylated benzoic acid derivatives |
| DE4020053A1 (de) * | 1990-01-31 | 1991-08-01 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-methyl-pyridin |
| DE4020052A1 (de) * | 1990-06-23 | 1992-01-02 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-methyl-pyridin |
| US5502194A (en) * | 1992-02-19 | 1996-03-26 | Bayer Aktiengesellschaft | Process for the preparation of 2-halogeno-pyridine derivatives |
| KR100309871B1 (ko) | 1999-02-24 | 2001-10-29 | 윤종용 | (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법 |
| SE9801923D0 (sv) | 1998-05-29 | 1998-05-29 | Independent Pharmaceutical Ab | Nicotine vaccine |
| US20040079259A1 (en) | 2002-10-29 | 2004-04-29 | Felix Manig | Method of manufacturing cementitious materials |
| FR2849657B1 (fr) | 2003-01-03 | 2005-07-15 | Arjo Wiggins | Feuille possedant un aspect iridescent, et son procede de fabrication |
-
2000
- 2000-03-21 SE SE0000933A patent/SE0000933D0/xx unknown
-
2001
- 2001-03-21 AU AU2001244913A patent/AU2001244913B2/en not_active Ceased
- 2001-03-21 WO PCT/SE2001/000599 patent/WO2001070730A1/en active IP Right Grant
- 2001-03-21 AT AT01918042T patent/ATE273295T1/de active
- 2001-03-21 ES ES01918042T patent/ES2225507T3/es not_active Expired - Lifetime
- 2001-03-21 DE DE60104825T patent/DE60104825T2/de not_active Expired - Lifetime
- 2001-03-21 PT PT01918042T patent/PT1265888E/pt unknown
- 2001-03-21 EP EP01918042A patent/EP1265888B1/en not_active Expired - Lifetime
- 2001-03-21 JP JP2001568933A patent/JP4370073B2/ja not_active Expired - Fee Related
- 2001-03-21 CA CA2402748A patent/CA2402748C/en not_active Expired - Fee Related
- 2001-03-21 TR TR2004/02787T patent/TR200402787T4/xx unknown
- 2001-03-21 US US10/221,175 patent/US6747156B2/en not_active Expired - Fee Related
- 2001-03-21 AU AU4491301A patent/AU4491301A/xx active Pending
-
2003
- 2003-02-28 HK HK03101515.1A patent/HK1051854B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2402748A1 (en) | 2001-09-27 |
| WO2001070730A1 (en) | 2001-09-27 |
| ATE273295T1 (de) | 2004-08-15 |
| US6747156B2 (en) | 2004-06-08 |
| AU4491301A (en) | 2001-10-03 |
| HK1051854B (zh) | 2005-02-18 |
| HK1051854A1 (en) | 2003-08-22 |
| EP1265888B1 (en) | 2004-08-11 |
| AU2001244913B2 (en) | 2005-08-11 |
| ES2225507T3 (es) | 2005-03-16 |
| DE60104825T2 (de) | 2005-09-29 |
| JP4370073B2 (ja) | 2009-11-25 |
| EP1265888A1 (en) | 2002-12-18 |
| TR200402787T4 (tr) | 2004-11-22 |
| CA2402748C (en) | 2010-02-16 |
| US20030187270A1 (en) | 2003-10-02 |
| JP2003529568A (ja) | 2003-10-07 |
| SE0000933D0 (sv) | 2000-03-21 |
| DE60104825D1 (de) | 2004-09-16 |
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