PT1194426E - Derivados de benzofurano - Google Patents

Derivados de benzofurano

Info

Publication number
PT1194426E
PT1194426E PT00949229T PT00949229T PT1194426E PT 1194426 E PT1194426 E PT 1194426E PT 00949229 T PT00949229 T PT 00949229T PT 00949229 T PT00949229 T PT 00949229T PT 1194426 E PT1194426 E PT 1194426E
Authority
PT
Portugal
Prior art keywords
benzofuran derivatives
benzofuran
derivatives
Prior art date
Application number
PT00949229T
Other languages
English (en)
Inventor
Henning Boettcher
Andreas Bathe
Bernd Helfert
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT1194426E publication Critical patent/PT1194426E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT00949229T 1999-07-10 2000-06-29 Derivados de benzofurano PT1194426E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19932314A DE19932314A1 (de) 1999-07-10 1999-07-10 Benzofuranderivate

Publications (1)

Publication Number Publication Date
PT1194426E true PT1194426E (pt) 2005-01-31

Family

ID=7914351

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00949229T PT1194426E (pt) 1999-07-10 2000-06-29 Derivados de benzofurano

Country Status (29)

Country Link
US (1) US6531503B1 (pt)
EP (1) EP1194426B1 (pt)
JP (1) JP4908706B2 (pt)
KR (1) KR100709378B1 (pt)
CN (1) CN1178934C (pt)
AR (1) AR024671A1 (pt)
AT (1) ATE273973T1 (pt)
AU (1) AU767413B2 (pt)
BR (1) BRPI0012329B8 (pt)
CA (1) CA2378603C (pt)
CZ (1) CZ301441B6 (pt)
DE (2) DE19932314A1 (pt)
DK (1) DK1194426T3 (pt)
ES (1) ES2226884T3 (pt)
HK (1) HK1047275B (pt)
HU (1) HU229135B1 (pt)
IL (2) IL147494A0 (pt)
MX (1) MXPA02000316A (pt)
MY (1) MY122667A (pt)
NO (1) NO328209B1 (pt)
PL (1) PL196477B1 (pt)
PT (1) PT1194426E (pt)
RU (1) RU2278862C2 (pt)
SI (1) SI1194426T1 (pt)
SK (1) SK287360B6 (pt)
TR (1) TR200200017T2 (pt)
UA (1) UA73310C2 (pt)
WO (1) WO2001004112A2 (pt)
ZA (1) ZA200201085B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006060597A1 (de) * 2006-12-21 2008-06-26 Merck Patent Gmbh Verfahren zur Herstellung von Benzofuran-2-carboxamiden
EP2110374A1 (en) * 2008-04-18 2009-10-21 Merck Sante Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators
MA33159B1 (fr) * 2009-03-10 2012-03-01 Takeda Pharmaceutical Derives de la coumarone
EP2566862B1 (en) 2010-05-06 2015-09-16 Bristol-Myers Squibb Company Benzofuranyl analogues as gpr119 modulators
CN102971311B (zh) 2010-05-06 2015-07-08 百时美施贵宝公司 作为gpr119调节剂的二环杂芳基化合物
CN102964323B (zh) * 2012-11-13 2015-03-25 苏州永健生物医药有限公司 一种5-（哌嗪-1-基）苯并呋喃-2-甲酰胺的合成方法
BR112015030248A2 (pt) * 2013-06-10 2017-07-25 Astellas Pharma Inc composto de amida heterocíclica aromática contendo nitrogênio bicíclico

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2724915A (en) * 1955-11-29 Snow remover
DE2757532A1 (de) * 1977-12-23 1979-07-05 Hoechst Ag N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
CN1129443A (zh) 1993-06-14 1996-08-21 美国辉瑞有限公司 仲胺用作治糖尿病和治肥胖病药物
DE4333254A1 (de) 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
DE19514567A1 (de) * 1995-04-20 1996-10-24 Merck Patent Gmbh Benzofurane

Also Published As

Publication number Publication date
MY122667A (en) 2006-04-29
PL353157A1 (en) 2003-10-20
IL147494A0 (en) 2002-08-14
ATE273973T1 (de) 2004-09-15
JP2003504364A (ja) 2003-02-04
WO2001004112A3 (de) 2001-08-02
PL196477B1 (pl) 2008-01-31
DE19932314A1 (de) 2001-01-11
HU229135B1 (en) 2013-08-28
TR200200017T2 (tr) 2002-05-21
CZ301441B6 (cs) 2010-03-03
HUP0201903A3 (en) 2005-02-28
HK1047275A1 (en) 2003-02-14
SI1194426T1 (en) 2005-02-28
NO328209B1 (no) 2010-01-11
SK287360B6 (sk) 2010-08-09
SK62002A3 (en) 2002-05-09
AR024671A1 (es) 2002-10-23
DK1194426T3 (da) 2004-12-20
JP4908706B2 (ja) 2012-04-04
KR100709378B1 (ko) 2007-04-20
EP1194426B1 (de) 2004-08-18
CZ200211A3 (cs) 2002-04-17
UA73310C2 (en) 2005-07-15
BR0012329B1 (pt) 2013-03-19
CN1356996A (zh) 2002-07-03
CN1178934C (zh) 2004-12-08
HUP0201903A2 (en) 2002-10-28
CA2378603A1 (en) 2001-01-18
AU767413B2 (en) 2003-11-06
ES2226884T3 (es) 2005-04-01
BR0012329A (pt) 2002-03-19
HK1047275B (zh) 2005-09-02
KR20020016815A (ko) 2002-03-06
AU6266500A (en) 2001-01-30
RU2278862C2 (ru) 2006-06-27
WO2001004112A2 (de) 2001-01-18
NO20020095D0 (no) 2002-01-09
US6531503B1 (en) 2003-03-11
BRPI0012329B8 (pt) 2021-05-25
EP1194426A2 (de) 2002-04-10
DE50007501D1 (de) 2004-09-23
CA2378603C (en) 2010-05-11
ZA200201085B (en) 2003-07-30
MXPA02000316A (es) 2002-07-30
IL147494A (en) 2008-03-20
NO20020095L (no) 2002-01-09

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