PT1150717E - Sais de libertacao prolongada de peptidos farmaceuticamente activos e sua producao - Google Patents

Sais de libertacao prolongada de peptidos farmaceuticamente activos e sua producao

Info

Publication number
PT1150717E
PT1150717E PT00906245T PT00906245T PT1150717E PT 1150717 E PT1150717 E PT 1150717E PT 00906245 T PT00906245 T PT 00906245T PT 00906245 T PT00906245 T PT 00906245T PT 1150717 E PT1150717 E PT 1150717E
Authority
PT
Portugal
Prior art keywords
releases
production
pharmaceutically active
active peptides
prolonged liberation
Prior art date
Application number
PT00906245T
Other languages
English (en)
Inventor
Damm Michael
Bauer Horst
Deger Wolfgang
Sarlikiotis Werner
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of PT1150717E publication Critical patent/PT1150717E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT00906245T 1999-02-08 2000-01-29 Sais de libertacao prolongada de peptidos farmaceuticamente activos e sua producao PT1150717E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11907699P 1999-02-08 1999-02-08

Publications (1)

Publication Number Publication Date
PT1150717E true PT1150717E (pt) 2005-10-31

Family

ID=22382454

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00906245T PT1150717E (pt) 1999-02-08 2000-01-29 Sais de libertacao prolongada de peptidos farmaceuticamente activos e sua producao

Country Status (31)

Country Link
EP (1) EP1150717B1 (pt)
JP (1) JP2002536421A (pt)
KR (1) KR100661768B1 (pt)
CN (1) CN1203897C (pt)
AR (1) AR022537A1 (pt)
AT (1) ATE298252T1 (pt)
AU (1) AU768882B2 (pt)
BG (1) BG65581B1 (pt)
BR (1) BR0008786A (pt)
CA (1) CA2360110C (pt)
CO (1) CO5160256A1 (pt)
CZ (1) CZ20012841A3 (pt)
DE (1) DE60020939T2 (pt)
DK (1) DK1150717T3 (pt)
ES (1) ES2242601T3 (pt)
HK (1) HK1044719B (pt)
HU (1) HUP0200127A3 (pt)
IL (2) IL144739A0 (pt)
MX (1) MXPA01007983A (pt)
NO (1) NO20013851L (pt)
NZ (1) NZ513748A (pt)
PL (1) PL196094B1 (pt)
PT (1) PT1150717E (pt)
RU (1) RU2239457C2 (pt)
SI (1) SI1150717T1 (pt)
SK (1) SK285358B6 (pt)
TR (1) TR200102289T2 (pt)
TW (1) TWI237568B (pt)
UA (1) UA72502C2 (pt)
WO (1) WO2000047234A1 (pt)
ZA (1) ZA200106467B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100452752B1 (ko) * 2000-04-18 2004-10-12 주식회사 펩트론 단백질 함유 서방성 제제를 제조하는 방법 및 그 제제
US7098305B2 (en) * 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
US6818613B2 (en) 2001-11-07 2004-11-16 Ortho-Mcneil Pharmaceutical, Inc. Aqueous sustained-release formulations of proteins
US7214662B2 (en) 2001-11-27 2007-05-08 Zentaris Gmbh Injectable solution of an LHRH antagonist
US7884071B2 (en) * 2002-09-27 2011-02-08 Zentaris Gmbh Administration form for pharmaceutically active peptides with sustained release and method for the production thereof
EP1674082A1 (de) * 2004-12-22 2006-06-28 Zentaris GmbH Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
CN105878174B (zh) * 2016-04-26 2021-06-29 广州帝奇医药技术有限公司 一种固体分散体及其制备方法与应用
CN113368041B (zh) * 2020-07-17 2023-01-03 丽珠医药集团股份有限公司 药物组合物、缓释制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581169A (en) * 1982-12-21 1986-04-08 Syntex (U.S.A.) Inc. Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists
GB9211268D0 (en) * 1992-05-28 1992-07-15 Ici Plc Salts of basic peptides with carboxyterminated polyesters
CA2178592C (en) * 1993-12-09 2009-07-28 Jurgen Engel Long-acting injection suspensions and a process for their preparation
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
AU5678398A (en) * 1997-01-29 1998-08-18 Takeda Chemical Industries Ltd. Sustained-release microspheres, their production and use
DE19712718C2 (de) * 1997-03-26 1999-09-23 Asta Medica Ag Immobilisierte und aktivitätsstabilisierte Komplexe von LHRH-Antagonisten und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
CZ20012841A3 (cs) 2002-03-13
AU2799700A (en) 2000-08-29
BR0008786A (pt) 2001-11-06
HUP0200127A3 (en) 2002-08-28
IL144739A0 (en) 2002-06-30
CO5160256A1 (es) 2002-05-30
SK11312001A3 (sk) 2002-04-04
PL196094B1 (pl) 2007-12-31
TWI237568B (en) 2005-08-11
HUP0200127A2 (en) 2002-06-29
MXPA01007983A (es) 2004-03-26
EP1150717A1 (en) 2001-11-07
BG65581B1 (bg) 2009-01-30
AU768882B2 (en) 2004-01-08
UA72502C2 (uk) 2005-03-15
ATE298252T1 (de) 2005-07-15
NO20013851D0 (no) 2001-08-07
EP1150717B1 (en) 2005-06-22
HK1044719A1 (en) 2002-11-01
KR20020012158A (ko) 2002-02-15
IL144739A (en) 2009-09-22
DE60020939D1 (de) 2005-07-28
ES2242601T3 (es) 2005-11-16
KR100661768B1 (ko) 2006-12-28
WO2000047234A1 (en) 2000-08-17
DE60020939T2 (de) 2006-05-11
DK1150717T3 (da) 2005-09-19
ZA200106467B (en) 2001-12-19
CA2360110C (en) 2009-10-20
JP2002536421A (ja) 2002-10-29
NZ513748A (en) 2001-09-28
BG105864A (en) 2002-04-30
RU2239457C2 (ru) 2004-11-10
PL350054A1 (en) 2002-11-04
SK285358B6 (sk) 2006-11-03
TR200102289T2 (tr) 2001-12-21
CN1343129A (zh) 2002-04-03
SI1150717T1 (en) 2005-10-31
CN1203897C (zh) 2005-06-01
AR022537A1 (es) 2002-09-04
HK1044719B (zh) 2006-02-10
CA2360110A1 (en) 2000-08-17
NO20013851L (no) 2001-09-28

Similar Documents

Publication Publication Date Title
NL300952I2 (nl) Peramivir en farmaceutisch aanvaardbare zouten daarvan
CY2014003I1 (el) Φαρμακοτεχνικες μορφες εχινοκανδινης που περιεχουν επιφανειοδραστικα που σχηματιζουν μικκυλιο
LU91501I2 (fr) Sugammadex et ses sels pharmaceutiquement acceptables-BRIDION
NO20003721D0 (no) Farmasøytisk aktivt morfolinol
PT1221918E (pt) Administracao de drogas sub-tenon
IS5245A (is) Lyfjablanda úr ómeprasól
NO994438D0 (no) Terapeutisk aktive diarylpropylaminer samt fremstilling og anvendelse derav
PT1189895E (pt) Derivados de tiazole e oxazole e sua utilizacao farmaceutica
NO20071303L (no) Farmasoytiske preparater
FI20012462A (fi) Farmaseuttisia formulaatioita ja menetelmiä käsittäen intranasaalista morfiinia
NO20020771D0 (no) Forlenget frigjöringsformulering av et peptid
NO20015670D0 (no) Forbedrede farmasöytiske formuleringer
HUP0300334A3 (en) Pharmaceutical preparations and their manufacture
EP1575987A4 (en) CONJUGATES OF MEMBRANE TRANSLOCATION AGENTS AND PHARMACEUTICAL ACTION AGENTS
ATE273697T1 (de) Pharmazeutische levothyroxinzubereitung
PT1150717E (pt) Sais de libertacao prolongada de peptidos farmaceuticamente activos e sua producao
EP1308509A4 (en) NEW, PHYSIOLOGICALLY ACTIVE PEPTIDE AND ITS APPLICATIONS
EP1357129A4 (en) NEW PHYSIOLOGICALLY ACTIVE PEPTIDE AND USE THEREOF
HK1052882A1 (zh) 生物活躍劑及藥物
EP1275659A4 (en) PHYSIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE
FI974610A0 (fi) Farmaceutiskt preparat i gelform
NO20020794L (no) Meg-1-protein
GB0019101D0 (en) Biologically and therapeutically active agents
GB0019100D0 (en) Biologically and therapeutically active agents
GB0019096D0 (en) Biologically and therapeutically active agents against HIV-1