DK1150717T3 - Salte af farmaceutisk aktive peptider med vedholdende frigivelse af disse samt fremstilling deraf - Google Patents

Salte af farmaceutisk aktive peptider med vedholdende frigivelse af disse samt fremstilling deraf

Info

Publication number
DK1150717T3
DK1150717T3 DK00906245T DK00906245T DK1150717T3 DK 1150717 T3 DK1150717 T3 DK 1150717T3 DK 00906245 T DK00906245 T DK 00906245T DK 00906245 T DK00906245 T DK 00906245T DK 1150717 T3 DK1150717 T3 DK 1150717T3
Authority
DK
Denmark
Prior art keywords
salts
preparation
sustained release
pharmaceutically active
active peptides
Prior art date
Application number
DK00906245T
Other languages
English (en)
Inventor
Werner Sarlikiotis
Horst Bauer
Wolfgang Deger
Michael Damm
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Application granted granted Critical
Publication of DK1150717T3 publication Critical patent/DK1150717T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK00906245T 1999-02-08 2000-01-29 Salte af farmaceutisk aktive peptider med vedholdende frigivelse af disse samt fremstilling deraf DK1150717T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11907699P 1999-02-08 1999-02-08
PCT/EP2000/000697 WO2000047234A1 (en) 1999-02-08 2000-01-29 Sustained release salts of pharmaceutically active peptides and their production

Publications (1)

Publication Number Publication Date
DK1150717T3 true DK1150717T3 (da) 2005-09-19

Family

ID=22382454

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00906245T DK1150717T3 (da) 1999-02-08 2000-01-29 Salte af farmaceutisk aktive peptider med vedholdende frigivelse af disse samt fremstilling deraf

Country Status (31)

Country Link
EP (1) EP1150717B1 (da)
JP (1) JP2002536421A (da)
KR (1) KR100661768B1 (da)
CN (1) CN1203897C (da)
AR (1) AR022537A1 (da)
AT (1) ATE298252T1 (da)
AU (1) AU768882B2 (da)
BG (1) BG65581B1 (da)
BR (1) BR0008786A (da)
CA (1) CA2360110C (da)
CO (1) CO5160256A1 (da)
CZ (1) CZ20012841A3 (da)
DE (1) DE60020939T2 (da)
DK (1) DK1150717T3 (da)
ES (1) ES2242601T3 (da)
HK (1) HK1044719B (da)
HU (1) HUP0200127A3 (da)
IL (2) IL144739A0 (da)
MX (1) MXPA01007983A (da)
NO (1) NO20013851L (da)
NZ (1) NZ513748A (da)
PL (1) PL196094B1 (da)
PT (1) PT1150717E (da)
RU (1) RU2239457C2 (da)
SI (1) SI1150717T1 (da)
SK (1) SK285358B6 (da)
TR (1) TR200102289T2 (da)
TW (1) TWI237568B (da)
UA (1) UA72502C2 (da)
WO (1) WO2000047234A1 (da)
ZA (1) ZA200106467B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100452752B1 (ko) * 2000-04-18 2004-10-12 주식회사 펩트론 단백질 함유 서방성 제제를 제조하는 방법 및 그 제제
US7098305B2 (en) 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
US6818613B2 (en) 2001-11-07 2004-11-16 Ortho-Mcneil Pharmaceutical, Inc. Aqueous sustained-release formulations of proteins
US7214662B2 (en) 2001-11-27 2007-05-08 Zentaris Gmbh Injectable solution of an LHRH antagonist
MXPA05003318A (es) * 2002-09-27 2005-09-12 Zentaris Gmbh Forma de administracion para peptidos farmaceuticamente activos con liberacion sostenida y metodo para la produccion de los mismos.
EP1674082A1 (de) * 2004-12-22 2006-06-28 Zentaris GmbH Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
CN105878174B (zh) * 2016-04-26 2021-06-29 广州帝奇医药技术有限公司 一种固体分散体及其制备方法与应用
CN113368041B (zh) * 2020-07-17 2023-01-03 丽珠医药集团股份有限公司 药物组合物、缓释制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581169A (en) * 1982-12-21 1986-04-08 Syntex (U.S.A.) Inc. Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists
GB9211268D0 (en) * 1992-05-28 1992-07-15 Ici Plc Salts of basic peptides with carboxyterminated polyesters
CA2178592C (en) * 1993-12-09 2009-07-28 Jurgen Engel Long-acting injection suspensions and a process for their preparation
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
WO1998032423A1 (en) * 1997-01-29 1998-07-30 Takeda Chemical Industries, Ltd. Sustained-release microspheres, their production and use
DE19712718C2 (de) * 1997-03-26 1999-09-23 Asta Medica Ag Immobilisierte und aktivitätsstabilisierte Komplexe von LHRH-Antagonisten und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
EP1150717B1 (en) 2005-06-22
CA2360110C (en) 2009-10-20
DE60020939D1 (de) 2005-07-28
DE60020939T2 (de) 2006-05-11
BG105864A (en) 2002-04-30
SI1150717T1 (en) 2005-10-31
HUP0200127A3 (en) 2002-08-28
TWI237568B (en) 2005-08-11
ZA200106467B (en) 2001-12-19
AU768882B2 (en) 2004-01-08
CN1203897C (zh) 2005-06-01
NO20013851L (no) 2001-09-28
PL196094B1 (pl) 2007-12-31
RU2239457C2 (ru) 2004-11-10
HUP0200127A2 (en) 2002-06-29
CO5160256A1 (es) 2002-05-30
SK285358B6 (sk) 2006-11-03
IL144739A0 (en) 2002-06-30
ES2242601T3 (es) 2005-11-16
BR0008786A (pt) 2001-11-06
KR100661768B1 (ko) 2006-12-28
NO20013851D0 (no) 2001-08-07
CA2360110A1 (en) 2000-08-17
WO2000047234A1 (en) 2000-08-17
AR022537A1 (es) 2002-09-04
AU2799700A (en) 2000-08-29
TR200102289T2 (tr) 2001-12-21
PL350054A1 (en) 2002-11-04
KR20020012158A (ko) 2002-02-15
SK11312001A3 (sk) 2002-04-04
CN1343129A (zh) 2002-04-03
ATE298252T1 (de) 2005-07-15
CZ20012841A3 (cs) 2002-03-13
MXPA01007983A (es) 2004-03-26
EP1150717A1 (en) 2001-11-07
BG65581B1 (bg) 2009-01-30
HK1044719B (zh) 2006-02-10
HK1044719A1 (en) 2002-11-01
JP2002536421A (ja) 2002-10-29
PT1150717E (pt) 2005-10-31
NZ513748A (en) 2001-09-28
IL144739A (en) 2009-09-22
UA72502C2 (uk) 2005-03-15

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