PT1140195E - Emulsao do tipo oleo-em-agua com accao de proteccao contra lesoes de peroxidacao em orgaos humanos, sua producao e utilizacao - Google Patents
Emulsao do tipo oleo-em-agua com accao de proteccao contra lesoes de peroxidacao em orgaos humanos, sua producao e utilizacaoInfo
- Publication number
- PT1140195E PT1140195E PT99964607T PT99964607T PT1140195E PT 1140195 E PT1140195 E PT 1140195E PT 99964607 T PT99964607 T PT 99964607T PT 99964607 T PT99964607 T PT 99964607T PT 1140195 E PT1140195 E PT 1140195E
- Authority
- PT
- Portugal
- Prior art keywords
- oil
- action against
- human
- peroxidacae
- orgaos
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 4
- 230000003902 lesion Effects 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 4
- 229940087168 alpha tocopherol Drugs 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 238000005502 peroxidation Methods 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 229960000984 tocofersolan Drugs 0.000 abstract 2
- 239000002076 α-tocopherol Substances 0.000 abstract 2
- 235000004835 α-tocopherol Nutrition 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000010410 reperfusion Effects 0.000 abstract 1
- 239000011732 tocopherol Substances 0.000 abstract 1
- 229960001295 tocopherol Drugs 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19859045A DE19859045A1 (de) | 1998-12-21 | 1998-12-21 | Emulsion vom Typ Öl in Wasser mit Schutzwirkung gegen Peroxidationsschäden an menschlichen Organen, deren Herstellung und Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1140195E true PT1140195E (pt) | 2003-08-29 |
Family
ID=7891978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99964607T PT1140195E (pt) | 1998-12-21 | 1999-12-18 | Emulsao do tipo oleo-em-agua com accao de proteccao contra lesoes de peroxidacao em orgaos humanos, sua producao e utilizacao |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6676956B1 (https=) |
| EP (1) | EP1140195B1 (https=) |
| JP (1) | JP4624564B2 (https=) |
| CN (1) | CN1154511C (https=) |
| AT (1) | ATE235254T1 (https=) |
| DE (2) | DE19859045A1 (https=) |
| DK (1) | DK1140195T3 (https=) |
| ES (1) | ES2192098T3 (https=) |
| PT (1) | PT1140195E (https=) |
| WO (1) | WO2000037108A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008514606A (ja) * | 2004-09-24 | 2008-05-08 | リポ ケミカルズ インコーポレイテッド | 局所適用化合物のためのデリバリーシステム |
| CN100525753C (zh) * | 2005-11-15 | 2009-08-12 | 董英杰 | 辅酶q10亚微乳注射液及制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4950124A (https=) * | 1972-09-27 | 1974-05-15 | ||
| JPS57163313A (en) * | 1981-03-31 | 1982-10-07 | Nippon Shinyaku Co Ltd | Vitamin e pharmaceutical and its preparation |
| JPS58162517A (ja) * | 1982-03-19 | 1983-09-27 | Green Cross Corp:The | 脂溶性ビタミン含有脂肪乳剤 |
| IT1191608B (it) * | 1985-02-01 | 1988-03-23 | Zambon Spa | Composizione farmaceutica e forme farmaceutiche che la contengono |
| US4678808A (en) * | 1985-10-15 | 1987-07-07 | Baxter Travenol Laboratories, Inc. | Rapid acting intravenous emulsions of omega-3 fatty acid esters |
| JPH0262829A (ja) * | 1988-05-18 | 1990-03-02 | Nippon Kayaku Co Ltd | 虚血に基づく傷害の予防及び治療剤 |
| CA2153553A1 (en) * | 1994-07-13 | 1996-01-14 | Hidekazu Suzuki | Stable lipid emulsion |
| GB9514878D0 (en) | 1995-07-20 | 1995-09-20 | Danbiosyst Uk | Vitamin E as a solubilizer for drugs contained in lipid vehicles |
| DE19758157A1 (de) * | 1997-03-27 | 1998-10-01 | Sueddeutsche Kalkstickstoff | Homogene, Glycerophospholipide und polare oder lipophile Substanzen enthaltende, wasserfreie Formulierungen und Verfahren zu deren Herstellung |
| HK1039072A1 (zh) * | 1998-05-07 | 2002-04-12 | 科里克萨有限公司 | 佐剂组合物及其使用方法 |
-
1998
- 1998-12-21 DE DE19859045A patent/DE19859045A1/de not_active Withdrawn
-
1999
- 1999-12-18 EP EP99964607A patent/EP1140195B1/de not_active Expired - Lifetime
- 1999-12-18 AT AT99964607T patent/ATE235254T1/de active
- 1999-12-18 WO PCT/EP1999/010106 patent/WO2000037108A1/de not_active Ceased
- 1999-12-18 PT PT99964607T patent/PT1140195E/pt unknown
- 1999-12-18 US US09/868,789 patent/US6676956B1/en not_active Expired - Lifetime
- 1999-12-18 DK DK99964607T patent/DK1140195T3/da active
- 1999-12-18 DE DE59904788T patent/DE59904788D1/de not_active Expired - Lifetime
- 1999-12-18 CN CNB998147478A patent/CN1154511C/zh not_active Expired - Lifetime
- 1999-12-18 ES ES99964607T patent/ES2192098T3/es not_active Expired - Lifetime
- 1999-12-18 JP JP2000589218A patent/JP4624564B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1140195B1 (de) | 2003-03-26 |
| DE59904788D1 (de) | 2003-04-30 |
| WO2000037108A1 (de) | 2000-06-29 |
| JP4624564B2 (ja) | 2011-02-02 |
| ATE235254T1 (de) | 2003-04-15 |
| CN1331606A (zh) | 2002-01-16 |
| DK1140195T3 (da) | 2003-06-23 |
| US6676956B1 (en) | 2004-01-13 |
| DE19859045A1 (de) | 2000-06-29 |
| ES2192098T3 (es) | 2003-09-16 |
| HK1037527A1 (en) | 2002-02-15 |
| EP1140195A1 (de) | 2001-10-10 |
| CN1154511C (zh) | 2004-06-23 |
| JP2002532564A (ja) | 2002-10-02 |
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