PT1127872E - Tamiflu por uma reaccao de diels-alder - Google Patents
Tamiflu por uma reaccao de diels-alderInfo
- Publication number
- PT1127872E PT1127872E PT01103934T PT01103934T PT1127872E PT 1127872 E PT1127872 E PT 1127872E PT 01103934 T PT01103934 T PT 01103934T PT 01103934 T PT01103934 T PT 01103934T PT 1127872 E PT1127872 E PT 1127872E
- Authority
- PT
- Portugal
- Prior art keywords
- tamiflu
- diels
- alder
- reaction
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/52—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/26—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00103673 | 2000-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1127872E true PT1127872E (pt) | 2006-06-30 |
Family
ID=8167922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01103934T PT1127872E (pt) | 2000-02-22 | 2001-02-19 | Tamiflu por uma reaccao de diels-alder |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6403824B2 (fr) |
| EP (1) | EP1127872B1 (fr) |
| JP (1) | JP4954378B2 (fr) |
| KR (1) | KR100743305B1 (fr) |
| CN (1) | CN1280258C (fr) |
| AT (1) | ATE316952T1 (fr) |
| CA (1) | CA2337452C (fr) |
| DE (1) | DE60116909T2 (fr) |
| DK (1) | DK1127872T3 (fr) |
| ES (1) | ES2256096T3 (fr) |
| IN (1) | IN192890B (fr) |
| JO (1) | JO2251B1 (fr) |
| PT (1) | PT1127872E (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6518048B2 (en) * | 2000-04-10 | 2003-02-11 | Hoffmann-La Roche Inc. | Stereo-specific synthesis of shimikic acid derivatives with improved efficiency |
| US7122684B2 (en) | 2003-03-13 | 2006-10-17 | Roche Colorado Corporation | Process for preparing 1,2-diamino compounds |
| EP1602730A3 (fr) * | 2004-06-04 | 2006-01-25 | DSM IP Assets B.V. | Préparation biosynthétique de 4-amino-4-deoxychorismate (ADC) et de [3R,4R]-4-amino-3-hydroxycyclohexa-1,5-diene-1-acide carboxylique (3,4-CHA) |
| EP1791808B1 (fr) * | 2004-09-02 | 2010-07-14 | F.Hoffmann-La Roche Ag | Procede de preparation d'acide 4,5-diamino shikimique |
| US7977077B2 (en) | 2006-01-30 | 2011-07-12 | Board Of Trustees Of Michigan State University | Synthesis of intermediates of oseltamivir carboxylates |
| US20080009639A1 (en) * | 2006-07-10 | 2008-01-10 | Apotex Pharmachem Inc. | Preparation of oseltamivir phosphate (Tamiflu) and intermediates starting from D-glucose or D-xylose |
| WO2008077809A1 (fr) * | 2006-12-22 | 2008-07-03 | F. Hoffmann-La Roche Ag | Procédé de fabrication de dérivés 7-oxa-bicyclo |
| ES2392207T3 (es) * | 2007-09-18 | 2012-12-05 | F. Hoffmann-La Roche Ag | Proceso a partir de ácido shikímico para obtener oseltamivir fosfato |
| KR101049475B1 (ko) * | 2008-12-22 | 2011-07-15 | (주)팜스웰바이오 | 아자-바이사이클로[2.2.1]헵텐 유도체, 이의 제조방법 및 이를 이용한 오셀타미비르의 중간체의 제조방법 |
| JP5796762B2 (ja) * | 2010-10-18 | 2015-10-21 | 国立大学法人豊橋技術科学大学 | 光学活性なシクロヘキセン誘導体の製造方法 |
| CN102464596A (zh) * | 2010-11-10 | 2012-05-23 | 南开大学 | “一锅法”获得达菲合成反应的关键中间体 |
| CA2852465A1 (fr) | 2011-09-07 | 2013-03-14 | Shinshu University | Procede de fabrication d'un metabolite utile a partir d'un champignon filamenteux |
| CN105801445B (zh) * | 2016-04-13 | 2017-08-25 | 福建师范大学 | 一种具有抗菌活性的非蛋白质氨基酸及其制备方法 |
| US10385010B1 (en) * | 2018-03-28 | 2019-08-20 | Georgia State University Research Foundation, Inc. | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA99001697A (es) | 1996-08-23 | 2004-04-05 | Gilead Sciences Inc | Preparacion de derivados de carboxilato de ciclohexeno. |
| WO1999014185A1 (fr) | 1997-09-17 | 1999-03-25 | Gilead Sciences, Inc. | Composes contenant des chaines fermees a six elements, procedes de preparation de ces composes, et leur utilisation comme medicaments |
| BR0010525A (pt) | 1999-10-19 | 2002-11-26 | Abbott Lab | cido 1-ciclo-hexeno-1-carboxìlico e 1-ciclo-hexeno-1carboxilatos como inibidores de neuraminidase |
-
2001
- 2001-02-06 US US09/777,277 patent/US6403824B2/en not_active Expired - Lifetime
- 2001-02-16 CA CA002337452A patent/CA2337452C/fr not_active Expired - Lifetime
- 2001-02-16 JP JP2001039289A patent/JP4954378B2/ja not_active Expired - Fee Related
- 2001-02-18 JO JO200122A patent/JO2251B1/en active
- 2001-02-19 AT AT01103934T patent/ATE316952T1/de active
- 2001-02-19 EP EP01103934A patent/EP1127872B1/fr not_active Expired - Lifetime
- 2001-02-19 ES ES01103934T patent/ES2256096T3/es not_active Expired - Lifetime
- 2001-02-19 DE DE60116909T patent/DE60116909T2/de not_active Expired - Lifetime
- 2001-02-19 DK DK01103934T patent/DK1127872T3/da active
- 2001-02-19 PT PT01103934T patent/PT1127872E/pt unknown
- 2001-02-20 IN IN153MA2001 patent/IN192890B/en unknown
- 2001-02-20 KR KR1020010008380A patent/KR100743305B1/ko active IP Right Grant
- 2001-02-21 CN CNB011046805A patent/CN1280258C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE316952T1 (de) | 2006-02-15 |
| JP4954378B2 (ja) | 2012-06-13 |
| ES2256096T3 (es) | 2006-07-16 |
| CN1310170A (zh) | 2001-08-29 |
| JO2251B1 (en) | 2004-10-07 |
| DE60116909D1 (de) | 2006-04-13 |
| EP1127872B1 (fr) | 2006-02-01 |
| CN1280258C (zh) | 2006-10-18 |
| US20020006960A1 (en) | 2002-01-17 |
| KR20010083189A (ko) | 2001-08-31 |
| DK1127872T3 (da) | 2006-06-12 |
| DE60116909T2 (de) | 2006-09-28 |
| JP2001288152A (ja) | 2001-10-16 |
| IN192890B (fr) | 2004-05-29 |
| CA2337452C (fr) | 2008-04-15 |
| KR100743305B1 (ko) | 2007-07-26 |
| US6403824B2 (en) | 2002-06-11 |
| EP1127872A1 (fr) | 2001-08-29 |
| CA2337452A1 (fr) | 2001-08-22 |
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