PT1095940E - Contem derivados de 9-(3,5-dimetoxifenil)-5,8,8a,9-tetra-hidrofuro[3',4':6,7]nafto[2,3-d][1,3]dioxol-6(5ah)-ona,processo para a sua preparacao e as composicoes farmaceuticas que os - Google Patents

Contem derivados de 9-(3,5-dimetoxifenil)-5,8,8a,9-tetra-hidrofuro[3',4':6,7]nafto[2,3-d][1,3]dioxol-6(5ah)-ona,processo para a sua preparacao e as composicoes farmaceuticas que os

Info

Publication number
PT1095940E
PT1095940E PT00402985T PT00402985T PT1095940E PT 1095940 E PT1095940 E PT 1095940E PT 00402985 T PT00402985 T PT 00402985T PT 00402985 T PT00402985 T PT 00402985T PT 1095940 E PT1095940 E PT 1095940E
Authority
PT
Portugal
Prior art keywords
alkyl
aryl
nr3r4
arylalkyl
halo
Prior art date
Application number
PT00402985T
Other languages
English (en)
Inventor
Claude Monneret
Alain Pierre
Bruno Pfeiffer
Ghanem Atassi
Pierre Renard
Philippe Meresse
Emmanuel Bertounesque
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of PT1095940E publication Critical patent/PT1095940E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT00402985T 1999-10-28 2000-10-27 Contem derivados de 9-(3,5-dimetoxifenil)-5,8,8a,9-tetra-hidrofuro[3',4':6,7]nafto[2,3-d][1,3]dioxol-6(5ah)-ona,processo para a sua preparacao e as composicoes farmaceuticas que os PT1095940E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9913514A FR2800374B1 (fr) 1999-10-28 1999-10-28 Nouveaux derives de 9-(3,5-dimethoxyphenyl)-5,8,8a,9- tetrahydrofuro[3',4':6,7]naphto[2,3-d] [1,3]dioxol-6(5ah)- one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
PT1095940E true PT1095940E (pt) 2004-10-29

Family

ID=9551486

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00402985T PT1095940E (pt) 1999-10-28 2000-10-27 Contem derivados de 9-(3,5-dimetoxifenil)-5,8,8a,9-tetra-hidrofuro[3',4':6,7]nafto[2,3-d][1,3]dioxol-6(5ah)-ona,processo para a sua preparacao e as composicoes farmaceuticas que os

Country Status (23)

Country Link
US (1) US6281198B1 (pt)
EP (1) EP1095940B1 (pt)
JP (1) JP3426206B2 (pt)
KR (1) KR100448526B1 (pt)
CN (1) CN1155601C (pt)
AT (1) ATE271558T1 (pt)
AU (1) AU774049B2 (pt)
BR (1) BR0005123A (pt)
CA (1) CA2324495A1 (pt)
DE (1) DE60012287T2 (pt)
DK (1) DK1095940T3 (pt)
EA (1) EA004440B1 (pt)
ES (1) ES2225052T3 (pt)
FR (1) FR2800374B1 (pt)
HK (1) HK1036276A1 (pt)
HU (1) HUP0004193A3 (pt)
MX (1) MXPA00010225A (pt)
NO (1) NO20005390L (pt)
NZ (1) NZ507831A (pt)
PL (1) PL343540A1 (pt)
PT (1) PT1095940E (pt)
SI (1) SI1095940T1 (pt)
ZA (1) ZA200006078B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176236B2 (en) * 2002-06-21 2007-02-13 University Of North Carolina At Chapel Hill Water-soluble etoposide analogs and methods of use thereof
US6566393B1 (en) 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof
EP1599485A2 (en) * 2003-02-18 2005-11-30 Ranbaxy Laboratories, Ltd. Podophyllotoxin derivatives as antitumor agents
CN101544652B (zh) * 2009-04-29 2011-06-15 南通大学 硫脲类表鬼臼毒素化合物及其制备方法和用途
JP5892508B2 (ja) * 2011-05-23 2016-03-23 国立大学法人 鹿児島大学 抗腫瘍剤及びその製造方法
CN102875564B (zh) * 2012-09-29 2015-10-21 湖北工业大学 具抗肿瘤活性的氮取代鬼臼类衍生物及其制备方法和用途
WO2014102889A1 (ja) * 2012-12-25 2014-07-03 国立大学法人鹿児島大学 抗腫瘍剤及びその製造方法
CN103613600B (zh) * 2013-11-15 2017-01-04 湖北工业大学 具抗肿瘤活性的苯胺基鬼臼类衍生物及其制备方法和用途
JP6326966B2 (ja) * 2014-05-26 2018-05-23 ユニマテック株式会社 含フッ素ウレタン（メタ）アクリレートの製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE335139B (pt) * 1964-08-12 1971-05-17 Sandoz Ag
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフイロトキシン誘導体
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
FR2739857B1 (fr) * 1995-10-12 1998-01-02 Pf Medicament Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Also Published As

Publication number Publication date
EP1095940A3 (fr) 2001-10-24
BR0005123A (pt) 2001-05-29
KR20010040195A (ko) 2001-05-15
PL343540A1 (en) 2001-05-07
CA2324495A1 (fr) 2001-04-28
US6281198B1 (en) 2001-08-28
MXPA00010225A (es) 2002-08-06
EA200001001A2 (ru) 2001-04-23
DE60012287D1 (de) 2004-08-26
NO20005390D0 (no) 2000-10-26
AU774049B2 (en) 2004-06-17
ES2225052T3 (es) 2005-03-16
ZA200006078B (en) 2001-05-18
ATE271558T1 (de) 2004-08-15
DK1095940T3 (da) 2004-11-22
NO20005390L (no) 2001-04-30
DE60012287T2 (de) 2005-07-21
HU0004193D0 (pt) 2001-01-29
NZ507831A (en) 2001-08-31
CN1296008A (zh) 2001-05-23
HUP0004193A2 (hu) 2001-08-28
AU6959700A (en) 2001-05-03
FR2800374B1 (fr) 2002-06-28
SI1095940T1 (en) 2004-10-31
EA200001001A3 (ru) 2001-06-25
CN1155601C (zh) 2004-06-30
EP1095940B1 (fr) 2004-07-21
JP2001131182A (ja) 2001-05-15
HUP0004193A3 (en) 2002-08-28
JP3426206B2 (ja) 2003-07-14
HK1036276A1 (en) 2001-12-28
FR2800374A1 (fr) 2001-05-04
KR100448526B1 (ko) 2004-09-13
EP1095940A2 (fr) 2001-05-02
EA004440B1 (ru) 2004-04-29

Similar Documents

Publication Publication Date Title
PE20021010A1 (es) Derivados espirociclicos como inhibidores de fosfodiesterasa-7
ES2062458T3 (es) Derivados del 1,2-benzisoxazol, sus procedimientos de preparacion y las composiciones farmaceuticas que los contienen.
EA200300391A1 (ru) Имидазольные соединения, арил- или гетероарилконденсированные, в качестве противовоспалительных и анальгетических средств
PT1078928E (pt) Derivados da piridina processo para a sua preparacao e as composicoes farmaceuticas que os contem
AR034553A1 (es) Triazolopirimidinas sustituidas, medicamento que los contienen, composiciones farmaceuticas y el uso de dichos derivados para la fabricacion de medicamentos como agentes anticancerosos
AR020661A1 (es) Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
PT1095940E (pt) Contem derivados de 9-(3,5-dimetoxifenil)-5,8,8a,9-tetra-hidrofuro[3',4':6,7]nafto[2,3-d][1,3]dioxol-6(5ah)-ona,processo para a sua preparacao e as composicoes farmaceuticas que os
AR036094A1 (es) Compuestos derivados de acido sulfonico, composicion farmaceutica y su uso en la preparacion de medicamentos
ES2118203T3 (es) Nuevos derivados benzopiranicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
AR054707A1 (es) Derivados de octahidropirrolo 3,4-c pirrol, un procedimiento para su preparacion, una composicion farmaceutica y uso del compuesto para la fabricacion de un medicamento
PE20050393A1 (es) Compuestos de benzopirano para uso en el tratamiento y la prevencion de afecciones relacionadas con la inflamacion
PT1061081E (pt) Novos derivados de carboxilato de 7-oxo-2,3,7,14-tetra-hidro-1h-benzo(b)pirano(3,2-h)acridina processo para a sua preparacao e as composicoes farmaceuticas que os contem
EA200200241A1 (ru) Новые производные изоиндолоиндолона, способ их получения и содержащие их фармацевтические композиции
PT92189A (pt) Processo para a preparacao de derivados de difenilacetamidas e de composicoes farmaceuticas que os contem
BR0201312A (pt) Compostos de pirimidin-4-ona, processo para sua preparação e composições farmacêuticas contendo os referidos
ES2123038T3 (es) Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
EA200300460A1 (ru) НОВЫЕ ПРОИЗВОДНЫЕ м-АМИНОФЕНИЛИМИНОИМИДАЗОЛИДИНА ДЛЯ ЛЕЧЕНИЯ НЕДЕРЖАНИЯ МОЧИ
AR000267A1 (pt)
GT199900186A (es) Derivados benzopirano sustituidos para el tratamiento de inflamaciones.