PT1064281E - Derivados de distamicina benzo-heterociclicos processo para os preparar e a sua utilizacao como agentes antitumorais - Google Patents
Derivados de distamicina benzo-heterociclicos processo para os preparar e a sua utilizacao como agentes antitumoraisInfo
- Publication number
- PT1064281E PT1064281E PT99915665T PT99915665T PT1064281E PT 1064281 E PT1064281 E PT 1064281E PT 99915665 T PT99915665 T PT 99915665T PT 99915665 T PT99915665 T PT 99915665T PT 1064281 E PT1064281 E PT 1064281E
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- agents
- hydrogen
- distamicine
- antitumatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9806692.1A GB9806692D0 (en) | 1998-03-27 | 1998-03-27 | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1064281E true PT1064281E (pt) | 2005-10-31 |
Family
ID=10829461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99915665T PT1064281E (pt) | 1998-03-27 | 1999-03-17 | Derivados de distamicina benzo-heterociclicos processo para os preparar e a sua utilizacao como agentes antitumorais |
Country Status (10)
Country | Link |
---|---|
US (1) | US6458768B1 (pt) |
EP (1) | EP1064281B1 (pt) |
JP (1) | JP2002509930A (pt) |
AT (1) | ATE296300T1 (pt) |
AU (1) | AU3415599A (pt) |
DE (1) | DE69925472T2 (pt) |
ES (1) | ES2244188T3 (pt) |
GB (1) | GB9806692D0 (pt) |
PT (1) | PT1064281E (pt) |
WO (1) | WO1999050266A1 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
ATE265716T1 (de) * | 2000-02-16 | 2004-05-15 | Ericsson Telefon Ab L M | Stiftdrucker |
GB0011059D0 (en) * | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0015444D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0029004D0 (en) | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
US20030236198A1 (en) | 2001-06-13 | 2003-12-25 | Genesoft, Inc. | Antipathogenic benzamide compounds |
WO2002101073A2 (en) | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc. | Aryl-benzimidazole compounds having antiinfective activity |
CA2450628A1 (en) * | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc. | Benzothiophene compounds having antiinfective activity |
US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
US7498349B2 (en) | 2002-08-02 | 2009-03-03 | Genesoft Pharmaceuticals, Inc. | Biaryl compounds having anti-infective activity |
EP1556035A4 (en) | 2002-09-20 | 2006-09-13 | Genelabs Tech Inc | NEW AROMATIC COMPOUNDS WITH ANTIMYCOTIC OR ANTIBACTERIAL EFFECT |
CA2503119A1 (en) * | 2002-10-25 | 2004-05-13 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
WO2004052304A2 (en) | 2002-12-10 | 2004-06-24 | Oscient Pharmaceuticals Corporation | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif |
US8008332B2 (en) * | 2006-05-31 | 2011-08-30 | Takeda San Diego, Inc. | Substituted indazoles as glucokinase activators |
BRPI0912802A2 (pt) * | 2008-05-16 | 2015-10-13 | Takeda San Diego Inc | ativadores de glicoquinase |
WO2023209651A1 (en) * | 2022-04-29 | 2023-11-02 | Dong-A St Co., Ltd. | Bicycle compounds as tead inhibitor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8612218D0 (en) | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
IT1271456B (it) | 1993-03-01 | 1997-05-28 | Menarini Farma Ind | Composti pirrol-amidinici, e loro sali farmaceuticamente accettabili, processi di preparazione e composizioni farmaceutiche che li contengono |
GB9416005D0 (en) | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
WO1997028123A1 (en) * | 1996-02-02 | 1997-08-07 | Pharmacia & Upjohn S.P.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
GB9610079D0 (en) * | 1996-05-14 | 1996-07-17 | Pharmacia Spa | Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents |
GB9623522D0 (en) | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
-
1998
- 1998-03-27 GB GBGB9806692.1A patent/GB9806692D0/en not_active Ceased
-
1999
- 1999-03-17 WO PCT/EP1999/001823 patent/WO1999050266A1/en active IP Right Grant
- 1999-03-17 PT PT99915665T patent/PT1064281E/pt unknown
- 1999-03-17 JP JP2000541170A patent/JP2002509930A/ja not_active Withdrawn
- 1999-03-17 DE DE69925472T patent/DE69925472T2/de not_active Expired - Fee Related
- 1999-03-17 US US09/623,505 patent/US6458768B1/en not_active Expired - Fee Related
- 1999-03-17 ES ES99915665T patent/ES2244188T3/es not_active Expired - Lifetime
- 1999-03-17 EP EP99915665A patent/EP1064281B1/en not_active Expired - Lifetime
- 1999-03-17 AU AU34155/99A patent/AU3415599A/en not_active Abandoned
- 1999-03-17 AT AT99915665T patent/ATE296300T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1064281A1 (en) | 2001-01-03 |
DE69925472D1 (de) | 2005-06-30 |
ES2244188T3 (es) | 2005-12-01 |
DE69925472T2 (de) | 2006-02-02 |
JP2002509930A (ja) | 2002-04-02 |
EP1064281B1 (en) | 2005-05-25 |
GB9806692D0 (en) | 1998-05-27 |
ATE296300T1 (de) | 2005-06-15 |
AU3415599A (en) | 1999-10-18 |
WO1999050266A1 (en) | 1999-10-07 |
US6458768B1 (en) | 2002-10-01 |
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