PT1049487E - Tratamento de porfiria aguda interminente (pai) e outras doencas porfiricas - Google Patents

Tratamento de porfiria aguda interminente (pai) e outras doencas porfiricas

Info

Publication number
PT1049487E
PT1049487E PT99906067T PT99906067T PT1049487E PT 1049487 E PT1049487 E PT 1049487E PT 99906067 T PT99906067 T PT 99906067T PT 99906067 T PT99906067 T PT 99906067T PT 1049487 E PT1049487 E PT 1049487E
Authority
PT
Portugal
Prior art keywords
porphyria
enzyme
treatment
pbgd
analogue
Prior art date
Application number
PT99906067T
Other languages
English (en)
Inventor
Jens Fogh
Par Gellerfors
Original Assignee
Hemebiotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemebiotech As filed Critical Hemebiotech As
Publication of PT1049487E publication Critical patent/PT1049487E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PT99906067T 1998-01-27 1999-01-27 Tratamento de porfiria aguda interminente (pai) e outras doencas porfiricas PT1049487E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK11298 1998-01-27
DKPA199801748 1998-12-30

Publications (1)

Publication Number Publication Date
PT1049487E true PT1049487E (pt) 2002-10-31

Family

ID=26063333

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99906067T PT1049487E (pt) 1998-01-27 1999-01-27 Tratamento de porfiria aguda interminente (pai) e outras doencas porfiricas

Country Status (11)

Country Link
EP (1) EP1049487B1 (pt)
JP (1) JP2002501032A (pt)
AT (1) ATE217799T1 (pt)
AU (1) AU750143B2 (pt)
CA (1) CA2319096C (pt)
DE (1) DE69901536T2 (pt)
DK (1) DK1049487T3 (pt)
ES (1) ES2177240T3 (pt)
NO (1) NO327241B1 (pt)
PT (1) PT1049487E (pt)
WO (1) WO1999037325A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6537777B1 (en) 1998-07-27 2003-03-25 Hemebiotech A/S Human porphobilinogen deaminase sequences
AU774603B2 (en) * 1999-07-27 2004-07-01 Zymenex A/S Production of rhPBGD and new therapeutic methods for treating patients with acute intermittent porphyria (AIP) and other porphyric diseases
EP2532742B1 (en) 2004-01-30 2018-08-08 Shire Pharmaceuticals Ireland Limited Recombinant arylsulfatase A for reducing galatosyl sulphatide levels in a subject
SI2628746T1 (sl) 2006-04-04 2019-04-30 Chiesi Farmaceutici S.P.A. Proces za koncentriranje polipeptida
WO2010036118A1 (en) 2008-09-29 2010-04-01 Amsterdam Molecular Therapeutics (Amt) B.V. Porphobilinogen deaminase gene therapy
US10336992B2 (en) 2011-07-08 2019-07-02 Shire Human Genetic Therapies, Inc. Methods for purification of arylsulfatase A
MX367842B (es) 2012-02-07 2019-09-09 Global Bio Therapeutics Inc Método compartimentado de administración de ácidos nucleicos y composiciones y usos del mismo.
CA2896979C (en) 2013-01-09 2023-05-02 Shire Human Genetic Therapies, Inc. Methods for purification of arylsulfatase a
DK3030163T3 (da) 2013-08-08 2019-07-01 Global Bio Therapeutics Inc Klemmeindretning til minimalt invasive procedurer
CA3024624A1 (en) * 2016-05-18 2017-11-23 Modernatx, Inc. Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria
US11390854B2 (en) 2017-05-09 2022-07-19 Fundacion Para La Investigacion Medica Aplicada Human porphobilinogen deaminase derived proteins and polynucleotides and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2657345B2 (ja) * 1992-04-17 1997-09-24 新日本製鐵株式会社 医療用診断装置および疾患判断方法

Also Published As

Publication number Publication date
ES2177240T3 (es) 2002-12-01
ATE217799T1 (de) 2002-06-15
NO20003830L (no) 2000-09-27
EP1049487A2 (en) 2000-11-08
CA2319096C (en) 2007-07-03
DK1049487T3 (da) 2002-09-16
DE69901536D1 (de) 2002-06-27
DE69901536T2 (de) 2003-01-16
AU2609799A (en) 1999-08-09
WO1999037325A2 (en) 1999-07-29
JP2002501032A (ja) 2002-01-15
EP1049487B1 (en) 2002-05-22
AU750143B2 (en) 2002-07-11
WO1999037325A3 (en) 1999-09-30
NO20003830D0 (no) 2000-07-26
CA2319096A1 (en) 1999-07-29
NO327241B1 (no) 2009-05-18

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