PT1044005E - Formulacoes de oxidos de 1,2,4-benzotriazina - Google Patents

Formulacoes de oxidos de 1,2,4-benzotriazina

Info

Publication number
PT1044005E
PT1044005E PT98915529T PT98915529T PT1044005E PT 1044005 E PT1044005 E PT 1044005E PT 98915529 T PT98915529 T PT 98915529T PT 98915529 T PT98915529 T PT 98915529T PT 1044005 E PT1044005 E PT 1044005E
Authority
PT
Portugal
Prior art keywords
formulations
benzotriazine oxides
benzotriazine
treatment
oxides
Prior art date
Application number
PT98915529T
Other languages
English (en)
Inventor
Brown Stephen
Baker Edward
Original Assignee
Sanofi Synthelabo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo Inc filed Critical Sanofi Synthelabo Inc
Publication of PT1044005E publication Critical patent/PT1044005E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
PT98915529T 1997-04-21 1998-04-14 Formulacoes de oxidos de 1,2,4-benzotriazina PT1044005E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/837,637 US5827850A (en) 1995-09-25 1997-04-21 1,2,4-benzotriazine oxides formulations

Publications (1)

Publication Number Publication Date
PT1044005E true PT1044005E (pt) 2006-10-31

Family

ID=25275027

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98915529T PT1044005E (pt) 1997-04-21 1998-04-14 Formulacoes de oxidos de 1,2,4-benzotriazina

Country Status (13)

Country Link
US (2) US5827850A (pt)
EP (1) EP1044005B1 (pt)
JP (1) JP2001523248A (pt)
AT (1) ATE332139T1 (pt)
AU (1) AU6969098A (pt)
BR (1) BR9808958A (pt)
CA (1) CA2287257C (pt)
DE (1) DE69835167T8 (pt)
DK (1) DK1044005T3 (pt)
ES (1) ES2267183T3 (pt)
NO (1) NO325275B1 (pt)
PT (1) PT1044005E (pt)
WO (1) WO1998047512A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5624925A (en) * 1986-09-25 1997-04-29 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
NZ521436A (en) * 2002-09-17 2005-07-29 Auckland Uniservices Ltd DNA- targeted benzotriazine 1,4-dioxides and their use in cancer therapy
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
CA2456569A1 (en) * 2003-03-14 2004-09-14 Auckland Uniservices Limited Benzoazine mono-n-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments
CA2567574C (en) 2004-04-08 2013-01-08 Targegen, Inc. Benzotriazine inhibitors of kinases
NZ553492A (en) 2004-08-25 2010-11-26 Targegen Inc Triazole derivatives and methods of use
US7834178B2 (en) * 2006-03-01 2010-11-16 Bristol-Myers Squibb Company Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
CN101683319B (zh) * 2008-09-24 2012-09-05 杭州民生药业有限公司 一种替拉扎明非肠道给药含水制剂及其制备方法
CN101683346B (zh) * 2008-09-24 2015-04-01 杭州民生药业有限公司 一种替拉扎明非肠道含水制剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980779A (en) * 1972-02-01 1976-09-14 Bayer Aktiengesellschaft 3-Amino-1,2,4-benzotriazine-1,4-di-N-oxide compositions and method of using same
US4001410A (en) * 1972-02-01 1977-01-04 Bayer Aktiengesellschaft 3-amino-1,2,4-benzotriazine-1,4-di-n-oxide compositions and method of using same
US5175287A (en) * 1986-09-25 1992-12-29 S R I International Process for preparing 1,2,4-benzotriazine oxides
CN100366253C (zh) * 1995-09-25 2008-02-06 赛诺菲-安万特美国有限责任公司 1,2,4-苯并三嗪氧化物制剂

Also Published As

Publication number Publication date
NO995109D0 (no) 1999-10-20
DE69835167T2 (de) 2007-06-06
NO325275B1 (no) 2008-03-17
DE69835167T8 (de) 2007-12-06
JP2001523248A (ja) 2001-11-20
DE69835167D1 (de) 2006-08-17
BR9808958A (pt) 2000-08-01
EP1044005B1 (en) 2006-07-05
CA2287257C (en) 2007-06-12
AU6969098A (en) 1998-11-13
WO1998047512A1 (en) 1998-10-29
EP1044005A4 (en) 2001-08-08
ES2267183T3 (es) 2007-03-01
US5827850A (en) 1998-10-27
ATE332139T1 (de) 2006-07-15
NO995109L (no) 1999-12-21
CA2287257A1 (en) 1998-10-29
DK1044005T3 (da) 2006-09-25
EP1044005A1 (en) 2000-10-18
US6153610A (en) 2000-11-28

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