PT1029054E - Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir - Google Patents
Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir Download PDFInfo
- Publication number
- PT1029054E PT1029054E PT98954076T PT98954076T PT1029054E PT 1029054 E PT1029054 E PT 1029054E PT 98954076 T PT98954076 T PT 98954076T PT 98954076 T PT98954076 T PT 98954076T PT 1029054 E PT1029054 E PT 1029054E
- Authority
- PT
- Portugal
- Prior art keywords
- tir
- polypeptide
- coli
- bacterial
- encoded
- Prior art date
Links
- 101150065732 tir gene Proteins 0.000 title abstract 11
- 244000052616 bacterial pathogen Species 0.000 title abstract 4
- 230000001580 bacterial effect Effects 0.000 title 1
- 102000006240 membrane receptors Human genes 0.000 title 1
- 108020004084 membrane receptors Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 241000588724 Escherichia coli Species 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 230000000369 enteropathogenic effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000007469 Actins Human genes 0.000 abstract 1
- 108010085238 Actins Proteins 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 230000006911 nucleation Effects 0.000 abstract 1
- 238000010899 nucleation Methods 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000007781 signaling event Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6513097P | 1997-11-12 | 1997-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1029054E true PT1029054E (pt) | 2009-11-11 |
Family
ID=22060539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98954076T PT1029054E (pt) | 1997-11-12 | 1998-11-10 | Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1029054B1 (https=) |
| JP (2) | JP4410412B2 (https=) |
| AT (1) | ATE438721T1 (https=) |
| AU (1) | AU1137399A (https=) |
| CA (1) | CA2309559A1 (https=) |
| DE (1) | DE69841042D1 (https=) |
| ES (1) | ES2333630T3 (https=) |
| PT (1) | PT1029054E (https=) |
| WO (1) | WO1999024576A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901897D0 (en) * | 1999-01-29 | 1999-03-17 | Imp College Innovations Ltd | Biological material and use thereof |
| GB0013115D0 (en) * | 2000-05-31 | 2000-07-19 | Imp College Innovations Ltd | Biological materials and methods for use in the prevention or treatment of infections |
| AU2002218927B2 (en) | 2001-01-04 | 2007-08-30 | The University Of British Columbia | Enterohemorrhagic Escherichia coli vaccine |
| CA2339436A1 (fr) | 2001-03-15 | 2002-09-15 | Josee Harel | Production d'anticorps contre les facteurs de virulence associes aux souches d'escherichia coli aeec, et leur utilisation |
| BRPI0415816A (pt) | 2003-10-31 | 2006-12-26 | Univ British Columbia | composição, bactéria ou um preparado da mesma, método para detectar a presença de um patógeno de a/e em uma amostra, método para provocar uma resposta imunológica contra um patógeno de a/e ou um componente do mesmo em um animal, método para reduzir a colonização de um patógeno de a/e em um animal, método para reduzir a disseminação de um patógeno de a/e em um animal, método para o tratamento ou a prevenção da infecção por um patógeno de a/e, método para atenuar a virulência de um patógeno de a/e, método para a seleção de um composto que atenue a virulência de um patógeno e a/e, método para a produção de um polipeptìdio de patógeno de a/e, polipeptìdio recombinante, molécula de ácido nucléico isolada, vetor, célula hospedeira, uso da composição e kit |
| WO2008133659A2 (en) | 2006-11-29 | 2008-11-06 | Tufts University | Eschericia coli mutants and methods of use thereof |
| JP2012522522A (ja) | 2009-04-06 | 2012-09-27 | ユニバーシティー オヴ サスカチュワン | 志賀毒素産生大腸菌感染を処置及び予防するための方法並びに組成物 |
| EP2964240B1 (en) * | 2013-03-07 | 2018-10-24 | The General Hospital Corporation | Compositions and methods for bacterial delivery of polypeptides |
| US10702559B2 (en) | 2016-02-09 | 2020-07-07 | The General Hospital Corporation | Methods and compositions relating to engineered microbial cells |
| CN121537480B (zh) * | 2026-01-16 | 2026-04-17 | 湘潭大学 | 一种具有多靶点降脂活性的小球藻七肽tgplgsr及其制备方法和应用 |
-
1998
- 1998-11-10 AT AT98954076T patent/ATE438721T1/de active
- 1998-11-10 PT PT98954076T patent/PT1029054E/pt unknown
- 1998-11-10 AU AU11373/99A patent/AU1137399A/en not_active Abandoned
- 1998-11-10 ES ES98954076T patent/ES2333630T3/es not_active Expired - Lifetime
- 1998-11-10 DE DE69841042T patent/DE69841042D1/de not_active Expired - Lifetime
- 1998-11-10 CA CA002309559A patent/CA2309559A1/en not_active Abandoned
- 1998-11-10 JP JP2000520570A patent/JP4410412B2/ja not_active Expired - Fee Related
- 1998-11-10 EP EP98954076A patent/EP1029054B1/en not_active Expired - Lifetime
- 1998-11-10 WO PCT/CA1998/001042 patent/WO1999024576A1/en not_active Ceased
-
2009
- 2009-03-24 JP JP2009071999A patent/JP2009173667A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2309559A1 (en) | 1999-05-20 |
| JP4410412B2 (ja) | 2010-02-03 |
| JP2001522605A (ja) | 2001-11-20 |
| DE69841042D1 (de) | 2009-09-17 |
| AU1137399A (en) | 1999-05-31 |
| WO1999024576A1 (en) | 1999-05-20 |
| EP1029054A1 (en) | 2000-08-23 |
| ATE438721T1 (de) | 2009-08-15 |
| ES2333630T3 (es) | 2010-02-24 |
| EP1029054B1 (en) | 2009-08-05 |
| JP2009173667A (ja) | 2009-08-06 |
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