PT1029054E - Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir - Google Patents
Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir Download PDFInfo
- Publication number
- PT1029054E PT1029054E PT98954076T PT98954076T PT1029054E PT 1029054 E PT1029054 E PT 1029054E PT 98954076 T PT98954076 T PT 98954076T PT 98954076 T PT98954076 T PT 98954076T PT 1029054 E PT1029054 E PT 1029054E
- Authority
- PT
- Portugal
- Prior art keywords
- tir
- polypeptide
- coli
- bacterial
- encoded
- Prior art date
Links
- 101150065732 tir gene Proteins 0.000 title abstract 11
- 244000052616 bacterial pathogen Species 0.000 title abstract 4
- 230000001580 bacterial effect Effects 0.000 title 1
- 102000006240 membrane receptors Human genes 0.000 title 1
- 108020004084 membrane receptors Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 241000588724 Escherichia coli Species 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 230000000369 enteropathogenic effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000007469 Actins Human genes 0.000 abstract 1
- 108010085238 Actins Proteins 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 230000006911 nucleation Effects 0.000 abstract 1
- 238000010899 nucleation Methods 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000007781 signaling event Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6513097P | 1997-11-12 | 1997-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1029054E true PT1029054E (pt) | 2009-11-11 |
Family
ID=22060539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98954076T PT1029054E (pt) | 1997-11-12 | 1998-11-10 | Hp90: receptor membranar do hospedeiro para bactérias patogénicas codificado pelo gene bacteriano tir |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1029054B1 (https=) |
| JP (2) | JP4410412B2 (https=) |
| AT (1) | ATE438721T1 (https=) |
| AU (1) | AU1137399A (https=) |
| CA (1) | CA2309559A1 (https=) |
| DE (1) | DE69841042D1 (https=) |
| ES (1) | ES2333630T3 (https=) |
| PT (1) | PT1029054E (https=) |
| WO (1) | WO1999024576A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901897D0 (en) * | 1999-01-29 | 1999-03-17 | Imp College Innovations Ltd | Biological material and use thereof |
| GB0013115D0 (en) * | 2000-05-31 | 2000-07-19 | Imp College Innovations Ltd | Biological materials and methods for use in the prevention or treatment of infections |
| NZ527322A (en) * | 2001-01-04 | 2005-07-29 | Univ Saskatchewan | EHEC cell culture supernatant vaccine |
| CA2339436A1 (fr) | 2001-03-15 | 2002-09-15 | Josee Harel | Production d'anticorps contre les facteurs de virulence associes aux souches d'escherichia coli aeec, et leur utilisation |
| WO2005042746A1 (en) | 2003-10-31 | 2005-05-12 | The University Of British Columbia | Bacterial virulence factors and uses thereof |
| WO2008133659A2 (en) | 2006-11-29 | 2008-11-06 | Tufts University | Eschericia coli mutants and methods of use thereof |
| WO2010115278A1 (en) | 2009-04-06 | 2010-10-14 | University Of Saskatchewan | Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection |
| JP6283040B2 (ja) * | 2013-03-07 | 2018-02-21 | ザ ジェネラル ホスピタル コーポレイション | 細菌によるポリペプチド送達のための組成物および方法 |
| WO2017139366A1 (en) | 2016-02-09 | 2017-08-17 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Methods and compositions relating to engineered microbial cells |
| CN121537480B (zh) * | 2026-01-16 | 2026-04-17 | 湘潭大学 | 一种具有多靶点降脂活性的小球藻七肽tgplgsr及其制备方法和应用 |
-
1998
- 1998-11-10 PT PT98954076T patent/PT1029054E/pt unknown
- 1998-11-10 JP JP2000520570A patent/JP4410412B2/ja not_active Expired - Fee Related
- 1998-11-10 ES ES98954076T patent/ES2333630T3/es not_active Expired - Lifetime
- 1998-11-10 DE DE69841042T patent/DE69841042D1/de not_active Expired - Lifetime
- 1998-11-10 CA CA002309559A patent/CA2309559A1/en not_active Abandoned
- 1998-11-10 AU AU11373/99A patent/AU1137399A/en not_active Abandoned
- 1998-11-10 EP EP98954076A patent/EP1029054B1/en not_active Expired - Lifetime
- 1998-11-10 AT AT98954076T patent/ATE438721T1/de active
- 1998-11-10 WO PCT/CA1998/001042 patent/WO1999024576A1/en not_active Ceased
-
2009
- 2009-03-24 JP JP2009071999A patent/JP2009173667A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1029054A1 (en) | 2000-08-23 |
| ATE438721T1 (de) | 2009-08-15 |
| JP4410412B2 (ja) | 2010-02-03 |
| ES2333630T3 (es) | 2010-02-24 |
| CA2309559A1 (en) | 1999-05-20 |
| DE69841042D1 (de) | 2009-09-17 |
| EP1029054B1 (en) | 2009-08-05 |
| JP2001522605A (ja) | 2001-11-20 |
| AU1137399A (en) | 1999-05-31 |
| WO1999024576A1 (en) | 1999-05-20 |
| JP2009173667A (ja) | 2009-08-06 |
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