PT101731A - Processo para a preparacao de composicoes farmaceuticas que contem moleculas de adesao intercelular um seu derivado funcional ou anticorpos ou fragmentos de anticorpos capazes de ligacao a estas moleculas em conjunto com um produto imunossupressivo - Google Patents
Processo para a preparacao de composicoes farmaceuticas que contem moleculas de adesao intercelular um seu derivado funcional ou anticorpos ou fragmentos de anticorpos capazes de ligacao a estas moleculas em conjunto com um produto imunossupressivo Download PDFInfo
- Publication number
- PT101731A PT101731A PT101731A PT10173195A PT101731A PT 101731 A PT101731 A PT 101731A PT 101731 A PT101731 A PT 101731A PT 10173195 A PT10173195 A PT 10173195A PT 101731 A PT101731 A PT 101731A
- Authority
- PT
- Portugal
- Prior art keywords
- molecules
- antibodies
- immunosuppressive
- fragments
- lighting
- Prior art date
Links
- 102000016289 Cell Adhesion Molecules Human genes 0.000 title abstract 3
- 108010067225 Cell Adhesion Molecules Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title 1
- 230000001506 immunosuppresive effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25044688A | 1988-09-28 | 1988-09-28 | |
| US32448189A | 1989-03-16 | 1989-03-16 | |
| US37388289A | 1989-06-30 | 1989-06-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT101731A true PT101731A (pt) | 1996-04-30 |
| PT101731B PT101731B (pt) | 1997-04-30 |
Family
ID=27400322
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91834A PT91834B (pt) | 1988-09-28 | 1989-09-28 | Processo para a preparacao de moleculas de adesao intercelular e de ligantes que promovem a ligacao destas moleculas bem como de agentes terapeuticos e de diagnostico que os contem |
| PT101731A PT101731B (pt) | 1988-09-28 | 1995-06-27 | Processo para a preparacao de composicoes farmaceuticas que contem moleculas de adesao intercelular um seu derivado funcional ou anticorpos ou fragmentos de anticorpos capazes de ligacao a estas moleculas em conjunto com um produto imunossupressivo |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91834A PT91834B (pt) | 1988-09-28 | 1989-09-28 | Processo para a preparacao de moleculas de adesao intercelular e de ligantes que promovem a ligacao destas moleculas bem como de agentes terapeuticos e de diagnostico que os contem |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0365837B1 (pt) |
| AT (2) | ATE125708T1 (pt) |
| CA (1) | CA1341185C (pt) |
| DE (2) | DE68923675T2 (pt) |
| ES (2) | ES2077572T3 (pt) |
| GR (1) | GR3017959T3 (pt) |
| HK (1) | HK1003105A1 (pt) |
| IE (1) | IE69975B1 (pt) |
| MX (1) | MX9203212A (pt) |
| NZ (1) | NZ230775A (pt) |
| PT (2) | PT91834B (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143298A (en) * | 1988-09-01 | 2000-11-07 | Bayer Corporation | Soluble truncated forms of ICAM-1 |
| US6051231A (en) * | 1988-09-01 | 2000-04-18 | Bayer Corporation | Antiviral methods and prepations |
| US6514936B1 (en) | 1988-09-01 | 2003-02-04 | Bayer Corporation | Antiviral methods using human rhinovirus receptor (ICAM-1) |
| ZA896668B (en) * | 1988-09-01 | 1990-06-27 | Molecular Therapeutics Inc | A human rhinovirus receptor protein that inhibits virus infectivity |
| ES2141076T3 (es) | 1988-09-01 | 2000-03-16 | Bayer Ag | Proteina del receptor de rinovirus humano que inhibe la infectividad del virus. |
| CA2008368C (en) * | 1989-01-24 | 2003-04-08 | Jeffrey Greve | Soluble molecule related to but distinct from icam-1 |
| US5776775A (en) * | 1989-02-21 | 1998-07-07 | Dana-Farber Cancer Institute | Anti-LAM 1-3 antibody and hybridoma |
| EP0432249B1 (en) | 1989-06-02 | 1996-09-25 | The Johns Hopkins University School Of Medicine | Monoclonal antibodies against leukocyte adhesion receptor beta-chain, methods of producing these antibodies and use therefore |
| US5686581A (en) * | 1990-07-20 | 1997-11-11 | Bayer Corporation | Multimeric form of human rhinovirus receptor protein |
| DE69131564T2 (de) * | 1990-07-20 | 2000-01-13 | Bayer Ag | Multimere Formen des menschlichen Rhinovirus-Rezeptorproteins |
| US6107461A (en) * | 1990-07-20 | 2000-08-22 | Bayer Corporation | Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use |
| US5686582A (en) * | 1990-07-20 | 1997-11-11 | Bayer Corporation | Multimeric forms of human rhinovirus receptor protein |
| US5288854A (en) * | 1990-11-28 | 1994-02-22 | Center For Blood Research, Inc. | Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1 |
| US5709859A (en) * | 1991-01-24 | 1998-01-20 | Bristol-Myers Squibb Company | Mixed specificity fusion proteins |
| AU667487B2 (en) * | 1991-10-01 | 1996-03-28 | General Hospital Corporation, The | Preventing allograft rejection with antibodies to adhesion molecules |
| US5861151A (en) * | 1991-12-20 | 1999-01-19 | Bristol-Myers Squibb Co | Soluble fusion molecules with binding specificity for cell adhesion molecules |
| WO1994000485A1 (en) * | 1992-06-22 | 1994-01-06 | Miles Inc. | Multimeric forms of human rhinovirus receptor protein |
| FR2756735B1 (fr) * | 1996-12-11 | 1999-02-26 | Thorel Jean Noel | Agent d'inhibition de l'expression de la proteine d'adherence icam-1 et compositions cosmetiques et pharmaceutiques le contenant |
| AU1207999A (en) * | 1997-10-30 | 1999-05-24 | Brigham And Women's Hospital | Control of lymphocyte localization by leep-cam activity |
| US20030035798A1 (en) | 2000-08-16 | 2003-02-20 | Fang Fang | Humanized antibodies |
| CH694344A5 (de) | 2000-09-29 | 2004-11-30 | Pesola Praez Swaagen Ag | Federwaage. |
| CA2898314A1 (en) | 2001-07-19 | 2003-07-31 | Perian Therapeutics, Inc. | Multimeric proteins and methods of making and using same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0289949B1 (en) * | 1987-05-04 | 1995-10-04 | Dana Farber Cancer Institute | Intercellular adhesion molecules, and their binding ligands |
| CA1341055C (en) * | 1987-12-08 | 2000-07-18 | Alan Mcclelland | Transfectant cell lines which express the major human rhinovirus receptor |
-
1989
- 1989-09-23 EP EP89117620A patent/EP0365837B1/en not_active Expired - Lifetime
- 1989-09-23 ES ES89117620T patent/ES2077572T3/es not_active Expired - Lifetime
- 1989-09-23 AT AT89117620T patent/ATE125708T1/de not_active IP Right Cessation
- 1989-09-23 DE DE68923675T patent/DE68923675T2/de not_active Expired - Lifetime
- 1989-09-23 ES ES93104664T patent/ES2201052T3/es not_active Expired - Lifetime
- 1989-09-23 EP EP93104664A patent/EP0606518B1/en not_active Expired - Lifetime
- 1989-09-23 AT AT93104664T patent/ATE246245T1/de not_active IP Right Cessation
- 1989-09-23 DE DE68929477T patent/DE68929477T2/de not_active Expired - Lifetime
- 1989-09-26 NZ NZ230775A patent/NZ230775A/en unknown
- 1989-09-26 CA CA000613303A patent/CA1341185C/en not_active Expired - Lifetime
- 1989-09-27 IE IE308989A patent/IE69975B1/en not_active IP Right Cessation
- 1989-09-28 PT PT91834A patent/PT91834B/pt not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203212A patent/MX9203212A/es unknown
-
1995
- 1995-06-27 PT PT101731A patent/PT101731B/pt not_active IP Right Cessation
- 1995-11-01 GR GR950403070T patent/GR3017959T3/el unknown
-
1998
- 1998-03-16 HK HK98102151A patent/HK1003105A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0365837A2 (en) | 1990-05-02 |
| ATE125708T1 (de) | 1995-08-15 |
| IE893089L (en) | 1990-03-28 |
| EP0606518A1 (en) | 1994-07-20 |
| ES2201052T3 (es) | 2004-03-16 |
| EP0365837A3 (en) | 1991-01-09 |
| PT91834B (pt) | 1996-08-30 |
| EP0606518B1 (en) | 2003-07-30 |
| DE68929477D1 (de) | 2003-09-04 |
| NZ230775A (en) | 1995-03-28 |
| GR3017959T3 (en) | 1996-02-29 |
| PT91834A (pt) | 1990-03-30 |
| DE68929477T2 (de) | 2004-06-03 |
| ATE246245T1 (de) | 2003-08-15 |
| IE69975B1 (en) | 1996-10-16 |
| ES2077572T3 (es) | 1995-12-01 |
| PT101731B (pt) | 1997-04-30 |
| DE68923675T2 (de) | 1996-02-15 |
| CA1341185C (en) | 2001-02-20 |
| DE68923675D1 (de) | 1995-09-07 |
| HK1003105A1 (en) | 1998-10-09 |
| EP0365837B1 (en) | 1995-08-02 |
| MX9203212A (es) | 1992-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT101731A (pt) | Processo para a preparacao de composicoes farmaceuticas que contem moleculas de adesao intercelular um seu derivado funcional ou anticorpos ou fragmentos de anticorpos capazes de ligacao a estas moleculas em conjunto com um produto imunossupressivo | |
| IL86246A0 (en) | Intercellular adhesion molecules and functional derivatives thereof,their production and antibodies against thereto | |
| NZ232833A (en) | Intercellular adhesion molecule-2 (icam-2) and functional derivatives thereof | |
| FI893916A0 (fi) | Alfa-subenhet av lfa-1 -leukocytadhesionsreceptor. | |
| MX168497B (es) | Ultrafiltracion de flujo tangencial por afinidad | |
| EP0364690A3 (en) | The alpha-subunit of the mac-1 leukocyte adhesion receptor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19960122 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20150629 |