PT100624A - Novos acidos dimetilamino-hidroxi-alcano-difosfonicos e seus sais, processo para a sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Novos acidos dimetilamino-hidroxi-alcano-difosfonicos e seus sais, processo para a sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number
PT100624A
PT100624A PT100624A PT10062492A PT100624A PT 100624 A PT100624 A PT 100624A PT 100624 A PT100624 A PT 100624A PT 10062492 A PT10062492 A PT 10062492A PT 100624 A PT100624 A PT 100624A
Authority
PT
Portugal
Prior art keywords
acano
dimethylamino
hydroxy
salts
contain
Prior art date
Application number
PT100624A
Other languages
English (en)
Other versions
PT100624B (pt
Inventor
Sergio Rosini
Maurizio Mian
Giuseppe Gucinai-Ricci
Original Assignee
Gentili Ist Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa
Publication of PT100624A publication Critical patent/PT100624A/pt
Publication of PT100624B publication Critical patent/PT100624B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT100624A 1991-06-26 1992-06-25 Novos acidos dimetilamino-hidroxi-alcano-difosfonicos e seus sais, processo para a sua preparacao e composicoes farmaceuticas que os contem PT100624B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITFI910160A IT1247034B (it) 1991-06-26 1991-06-26 Acidi dimetilamino-idrossi alchil difosfonici e loro sali, loro procedimento produttivo e composizioni farmaceutiche che li comprendono

Publications (2)

Publication Number Publication Date
PT100624A true PT100624A (pt) 1993-10-29
PT100624B PT100624B (pt) 1999-07-30

Family

ID=11349724

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100624A PT100624B (pt) 1991-06-26 1992-06-25 Novos acidos dimetilamino-hidroxi-alcano-difosfonicos e seus sais, processo para a sua preparacao e composicoes farmaceuticas que os contem

Country Status (8)

Country Link
EP (1) EP0592488A1 (pt)
JP (1) JPH06508833A (pt)
AU (1) AU2150792A (pt)
CA (1) CA2112250A1 (pt)
IT (1) IT1247034B (pt)
MX (1) MX9203205A (pt)
PT (1) PT100624B (pt)
WO (1) WO1993000348A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303672B1 (it) 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei
CA2451881A1 (fr) * 2001-07-16 2003-01-30 Universite Paris 13 Nouveaux derives de bisphosphonates, leurs preparations et utilisations
DE102014115154A1 (de) * 2014-10-17 2016-04-21 SCV-SpezialChemikalien-Vertrieb GmbH Konjugierte Bisphosphonate für die Diagnostik und Therapie von Knochenerkrankungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194748B (it) * 1981-02-12 1988-09-28 Gentili Ist Spa Composizioni farmaceutiche per il trattamento di osteopatie
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE3434667A1 (de) * 1984-09-21 1986-04-03 Henkel KGaA, 4000 Düsseldorf 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
IT1247034B (it) 1994-12-12
MX9203205A (es) 1994-06-30
ITFI910160A1 (it) 1992-12-26
AU2150792A (en) 1993-01-25
JPH06508833A (ja) 1994-10-06
EP0592488A1 (en) 1994-04-20
ITFI910160A0 (it) 1991-06-26
PT100624B (pt) 1999-07-30
WO1993000348A1 (en) 1993-01-07
CA2112250A1 (en) 1993-01-07

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Effective date: 19930914

FG3A Patent granted, date of granting

Effective date: 19990412

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Effective date: 20140414