PT1000062E - Agonistas triciclicos de vasopressina - Google Patents

Agonistas triciclicos de vasopressina

Info

Publication number
PT1000062E
PT1000062E PT98938017T PT98938017T PT1000062E PT 1000062 E PT1000062 E PT 1000062E PT 98938017 T PT98938017 T PT 98938017T PT 98938017 T PT98938017 T PT 98938017T PT 1000062 E PT1000062 E PT 1000062E
Authority
PT
Portugal
Prior art keywords
vasopressin
agonists
tricyclic
disorders
nocturia
Prior art date
Application number
PT98938017T
Other languages
English (en)
Inventor
Jay Donald Albright
Eugene John Trybulski
Albert John Molinari
Jehan Framroz Bagli
Mark Anthony Ashwell
John Paul Dusza
Peter Sinchun Chan
Amedeo Arturo Failli
Thomas Joseph Caggiano
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PT1000062E publication Critical patent/PT1000062E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT98938017T 1997-07-30 1998-07-24 Agonistas triciclicos de vasopressina PT1000062E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90336997A 1997-07-30 1997-07-30

Publications (1)

Publication Number Publication Date
PT1000062E true PT1000062E (pt) 2004-12-31

Family

ID=25417392

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98938017T PT1000062E (pt) 1997-07-30 1998-07-24 Agonistas triciclicos de vasopressina

Country Status (22)

Country Link
EP (1) EP1000062B1 (pt)
JP (1) JP4338305B2 (pt)
KR (1) KR100580805B1 (pt)
CN (1) CN1183134C (pt)
AR (1) AR016557A1 (pt)
AT (1) ATE277050T1 (pt)
AU (1) AU756959B2 (pt)
BR (1) BR9811585A (pt)
CA (1) CA2297406C (pt)
DE (1) DE69826487T2 (pt)
DK (1) DK1000062T3 (pt)
ES (1) ES2229525T3 (pt)
HU (1) HUP0002480A3 (pt)
IL (1) IL133788A0 (pt)
NO (1) NO315273B1 (pt)
NZ (1) NZ502449A (pt)
PT (1) PT1000062E (pt)
RU (1) RU2213094C2 (pt)
SI (1) SI1000062T1 (pt)
TW (1) TW502035B (pt)
WO (1) WO1999006409A1 (pt)
ZA (1) ZA986784B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7138393B2 (en) 1998-07-24 2006-11-21 Wyeth Biologically active vasopressin agonist metabolites
HU229074B1 (en) * 1999-01-19 2013-07-29 Ortho Mcneil Pharm Inc Tricyclic benzodiazepines as vasopressin receptor antagonists
AU7615200A (en) * 1999-09-27 2001-04-30 American Cyanamid Company Vasopressin agonist formulation and process
US6831079B1 (en) * 1999-09-27 2004-12-14 American Cyanamid Company Vasopressin agonist formulation and process
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
GB0015601D0 (en) * 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
US6900200B2 (en) * 2001-04-12 2005-05-31 Wyeth Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US6977254B2 (en) 2001-04-12 2005-12-20 Wyeth Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7109193B2 (en) 2001-04-12 2006-09-19 Wyeth Tricyclic diazepines tocolytic oxytocin receptor antagonists
US7326700B2 (en) 2001-04-12 2008-02-05 Wyeth Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7064120B2 (en) 2001-04-12 2006-06-20 Wyeth Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US6903087B2 (en) 2001-04-12 2005-06-07 Wyeth Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7202239B2 (en) 2001-04-12 2007-04-10 Wyeth Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
US7022699B2 (en) 2001-04-12 2006-04-04 Wyeth Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
EP1434763B1 (en) * 2001-10-12 2018-01-17 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin v1a antagonists
US7183271B2 (en) 2003-04-28 2007-02-27 Astellas Pharma Inc. 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
MX2007002248A (es) * 2004-08-25 2008-10-02 Pfizer Triazolobenzodiazepinas y su uso como antagonistas de vasopresina.
US9597314B2 (en) 2005-03-22 2017-03-21 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
DK2356123T3 (da) 2008-11-13 2012-10-15 Hoffmann La Roche Spiro-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulener
EP2308866A1 (de) 2009-10-09 2011-04-13 Bayer CropScience AG Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide
US8420633B2 (en) * 2010-03-31 2013-04-16 Hoffmann-La Roche Inc. Aryl-cyclohexyl-tetraazabenzo[e]azulenes
GB201005623D0 (en) 2010-04-01 2010-05-19 Vantia Ltd New polymorph
US8461151B2 (en) * 2010-04-13 2013-06-11 Hoffmann-La Roche Inc. Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes
US8481528B2 (en) * 2010-04-26 2013-07-09 Hoffmann-La Roche Inc. Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes
US8513238B2 (en) * 2010-05-10 2013-08-20 Hoffmann-La Roche Inc. Heteroaryl-cyclohexyl-tetraazabenzo[E]azulenes
CA2804001C (en) 2010-07-01 2021-02-09 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
US9828345B2 (en) 2013-02-28 2017-11-28 Bristol-Myers Squibb Company Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors
AR094929A1 (es) 2013-02-28 2015-09-09 Bristol Myers Squibb Co Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
BR112016022575A2 (pt) 2014-03-28 2017-08-15 Azevan Pharmaceuticals Inc Composições e métodos para o tratamento de doenças neurodegenerativas
CN111295373A (zh) 2017-09-15 2020-06-16 阿泽凡药物公司 用于治疗脑损伤的组合物和方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516774A (en) * 1993-07-29 1996-05-14 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5521173A (en) * 1995-01-17 1996-05-28 American Home Products Corporation Tricyclic benzazepine vasopressin antagonists
TW359669B (en) * 1995-12-15 1999-06-01 Otsuka Pharma Co Ltd Benzazepine derivatives

Also Published As

Publication number Publication date
RU2213094C2 (ru) 2003-09-27
ES2229525T3 (es) 2005-04-16
EP1000062B1 (en) 2004-09-22
NO315273B1 (no) 2003-08-11
NO20000242L (no) 2000-03-06
AR016557A1 (es) 2001-07-25
JP2001512125A (ja) 2001-08-21
NO20000242D0 (no) 2000-01-18
KR100580805B1 (ko) 2006-05-17
AU8663398A (en) 1999-02-22
AU756959B2 (en) 2003-01-30
ATE277050T1 (de) 2004-10-15
CA2297406C (en) 2009-02-24
DK1000062T3 (da) 2004-11-22
WO1999006409A1 (en) 1999-02-11
EP1000062A1 (en) 2000-05-17
CA2297406A1 (en) 1999-02-11
IL133788A0 (en) 2001-04-30
DE69826487D1 (de) 2004-10-28
BR9811585A (pt) 2000-09-26
CN1183134C (zh) 2005-01-05
TW502035B (en) 2002-09-11
DE69826487T2 (de) 2005-12-01
SI1000062T1 (en) 2004-12-31
ZA986784B (en) 2000-06-22
CN1272111A (zh) 2000-11-01
HUP0002480A2 (hu) 2000-11-28
JP4338305B2 (ja) 2009-10-07
NZ502449A (en) 2002-08-28
HUP0002480A3 (en) 2002-09-30
KR20010022398A (ko) 2001-03-15

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