PL87266B1 - - Google Patents
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- Publication number
- PL87266B1 PL87266B1 PL1971150029A PL15002971A PL87266B1 PL 87266 B1 PL87266 B1 PL 87266B1 PL 1971150029 A PL1971150029 A PL 1971150029A PL 15002971 A PL15002971 A PL 15002971A PL 87266 B1 PL87266 B1 PL 87266B1
- Authority
- PL
- Poland
- Prior art keywords
- antibiotic
- agar
- isolated
- streptomyces
- medium
- Prior art date
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- NTAHMPNXQOYXSX-WKSONYIQSA-N goldinodox Chemical compound C(/[C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(/C)=C/C=C/CNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O)C(C)(C)[C@H](\C=C\C=C/C)O1)O)=C\C=C\C=C(/C)C(=O)C1=C(O)C=CN(C)C1=O NTAHMPNXQOYXSX-WKSONYIQSA-N 0.000 claims description 114
- 230000003115 biocidal effect Effects 0.000 claims description 63
- 239000002609 medium Substances 0.000 claims description 37
- 238000000855 fermentation Methods 0.000 claims description 36
- 230000004151 fermentation Effects 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 33
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 30
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims description 22
- 241000187180 Streptomyces sp. Species 0.000 claims description 20
- 239000000284 extract Substances 0.000 claims description 16
- 229910052757 nitrogen Inorganic materials 0.000 claims description 15
- 238000000605 extraction Methods 0.000 claims description 14
- 150000003839 salts Chemical class 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000002904 solvent Substances 0.000 claims description 8
- 239000012736 aqueous medium Substances 0.000 claims description 4
- 238000002955 isolation Methods 0.000 claims description 4
- 150000001720 carbohydrates Chemical class 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000005227 gel permeation chromatography Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims description 2
- 230000002426 anti-panic effect Effects 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 229920001817 Agar Polymers 0.000 description 40
- 239000008272 agar Substances 0.000 description 40
- 239000000203 mixture Substances 0.000 description 23
- 239000000243 solution Substances 0.000 description 23
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 21
- FUZZWVXGSFPDMH-UHFFFAOYSA-M hexanoate Chemical compound CCCCCC([O-])=O FUZZWVXGSFPDMH-UHFFFAOYSA-M 0.000 description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 21
- 235000013312 flour Nutrition 0.000 description 19
- 235000015097 nutrients Nutrition 0.000 description 19
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 18
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 18
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 15
- 229920001353 Dextrin Polymers 0.000 description 15
- 239000004375 Dextrin Substances 0.000 description 15
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 15
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 13
- 229910052799 carbon Inorganic materials 0.000 description 13
- 244000144977 poultry Species 0.000 description 13
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 12
- 239000012153 distilled water Substances 0.000 description 12
- 235000001727 glucose Nutrition 0.000 description 12
- 239000008103 glucose Substances 0.000 description 12
- 159000000000 sodium salts Chemical class 0.000 description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 11
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 11
- 235000019797 dipotassium phosphate Nutrition 0.000 description 11
- 230000028070 sporulation Effects 0.000 description 11
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- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 9
- 241001465754 Metazoa Species 0.000 description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
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- 229910000019 calcium carbonate Inorganic materials 0.000 description 9
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- 229940041514 candida albicans extract Drugs 0.000 description 9
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- 229910052943 magnesium sulfate Inorganic materials 0.000 description 9
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- 229910052708 sodium Inorganic materials 0.000 description 9
- 239000011734 sodium Substances 0.000 description 9
- -1 Fe "1-1" Chemical compound 0.000 description 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 8
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- 102000004169 proteins and genes Human genes 0.000 description 8
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- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
- 240000003768 Solanum lycopersicum Species 0.000 description 7
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 7
- 239000012141 concentrate Substances 0.000 description 7
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- 238000002474 experimental method Methods 0.000 description 7
- 230000005764 inhibitory process Effects 0.000 description 7
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
- 241000287828 Gallus gallus Species 0.000 description 6
- 244000068988 Glycine max Species 0.000 description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000003242 anti bacterial agent Substances 0.000 description 6
- LXQXGFPPYLKKSD-UHFFFAOYSA-L disodium;2,2-diethylpropanedioate Chemical compound [Na+].[Na+].CCC(CC)(C([O-])=O)C([O-])=O LXQXGFPPYLKKSD-UHFFFAOYSA-L 0.000 description 6
- 238000004821 distillation Methods 0.000 description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
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- 241000193400 Bacillus simplex Species 0.000 description 5
- 101100283604 Caenorhabditis elegans pigk-1 gene Proteins 0.000 description 5
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 5
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 5
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 4
- 108010010803 Gelatin Proteins 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 4
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- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 4
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- PYMYPHUHKUWMLA-UHFFFAOYSA-N 2,3,4,5-tetrahydroxypentanal Chemical compound OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 3
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- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 2
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- 238000002329 infrared spectrum Methods 0.000 description 2
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- BJHIKXHVCXFQLS-UYFOZJQFSA-N keto-D-fructose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 2
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- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- SPOMEWBVWWDQBC-UHFFFAOYSA-K tripotassium;dihydrogen phosphate;hydrogen phosphate Chemical compound [K+].[K+].[K+].OP(O)([O-])=O.OP([O-])([O-])=O SPOMEWBVWWDQBC-UHFFFAOYSA-K 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Feed For Specific Animals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6438970A | 1970-08-14 | 1970-08-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL87266B1 true PL87266B1 (en, 2012) | 1976-06-30 |
Family
ID=22055625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1971150029A PL87266B1 (en, 2012) | 1970-08-14 | 1971-08-14 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US3708577A (en, 2012) |
| JP (2) | JPS5436232B1 (en, 2012) |
| AT (2) | AT306925B (en, 2012) |
| AU (1) | AU463383B2 (en, 2012) |
| BE (1) | BE771276A (en, 2012) |
| CA (1) | CA1050462A (en, 2012) |
| CH (2) | CH559515A5 (en, 2012) |
| CS (1) | CS158708B2 (en, 2012) |
| DD (1) | DD96255A5 (en, 2012) |
| DE (1) | DE2140322A1 (en, 2012) |
| DK (1) | DK131640C (en, 2012) |
| ES (1) | ES394210A1 (en, 2012) |
| FI (1) | FI48850C (en, 2012) |
| FR (1) | FR2102264B1 (en, 2012) |
| GB (1) | GB1308843A (en, 2012) |
| HU (1) | HU166412B (en, 2012) |
| IE (1) | IE35545B1 (en, 2012) |
| IL (1) | IL37491A (en, 2012) |
| IT (1) | IT1060353B (en, 2012) |
| NL (1) | NL7111193A (en, 2012) |
| NO (1) | NO135182C (en, 2012) |
| PL (1) | PL87266B1 (en, 2012) |
| RO (1) | RO64374A (en, 2012) |
| SE (3) | SE401775B (en, 2012) |
| SU (1) | SU404186A3 (en, 2012) |
| YU (1) | YU35460B (en, 2012) |
| ZA (1) | ZA714933B (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060013889A1 (en) * | 2004-07-16 | 2006-01-19 | Playford Raymond J | Colostrum-based treatment for irritable bowel syndrome |
| US7426440B2 (en) * | 2004-09-24 | 2008-09-16 | Nutritional Bioscience Ltd. | Repair and protection factor scoring method for bioactive agents |
| US20060068022A1 (en) * | 2004-09-29 | 2006-03-30 | Playford Raymond J | Bioactive agent compositions for repair of cell injuries |
| CN115850354A (zh) * | 2022-11-15 | 2023-03-28 | 中国科学院南海海洋研究所 | 一种聚酮类化合物efrotomycin及其制备方法和应用 |
-
1970
- 1970-08-14 US US00064389A patent/US3708577A/en not_active Expired - Lifetime
-
1971
- 1971-04-15 SE SE7500788A patent/SE401775B/xx unknown
- 1971-07-23 ZA ZA714933A patent/ZA714933B/xx unknown
- 1971-07-28 CH CH476674A patent/CH559515A5/xx not_active IP Right Cessation
- 1971-07-28 CH CH1116971A patent/CH560247A5/xx not_active IP Right Cessation
- 1971-08-11 RO RO7167953A patent/RO64374A/ro unknown
- 1971-08-11 DE DE19712140322 patent/DE2140322A1/de not_active Withdrawn
- 1971-08-12 IT IT7127472A patent/IT1060353B/it active
- 1971-08-12 IL IL37491A patent/IL37491A/xx unknown
- 1971-08-12 YU YU2078/71A patent/YU35460B/xx unknown
- 1971-08-12 FR FR7129553A patent/FR2102264B1/fr not_active Expired
- 1971-08-12 GB GB3792571A patent/GB1308843A/en not_active Expired
- 1971-08-13 ES ES394210A patent/ES394210A1/es not_active Expired
- 1971-08-13 AT AT709771A patent/AT306925B/de not_active IP Right Cessation
- 1971-08-13 IE IE1022/71A patent/IE35545B1/xx unknown
- 1971-08-13 JP JP6108271A patent/JPS5436232B1/ja active Pending
- 1971-08-13 CA CA120,508A patent/CA1050462A/en not_active Expired
- 1971-08-13 AT AT421872*7A patent/AT328279B/de active
- 1971-08-13 FI FI712270A patent/FI48850C/fi active
- 1971-08-13 DD DD157118A patent/DD96255A5/xx unknown
- 1971-08-13 AU AU32348/71A patent/AU463383B2/en not_active Expired
- 1971-08-13 NL NL7111193A patent/NL7111193A/xx not_active Application Discontinuation
- 1971-08-13 CS CS588171A patent/CS158708B2/cs unknown
- 1971-08-13 DK DK397971A patent/DK131640C/da active
- 1971-08-13 BE BE771276A patent/BE771276A/xx unknown
- 1971-08-13 NO NO3039/71A patent/NO135182C/no unknown
- 1971-08-13 SU SU1743977A patent/SU404186A3/ru active
- 1971-08-13 SE SE7110346A patent/SE393994B/xx unknown
- 1971-08-14 PL PL1971150029A patent/PL87266B1/pl unknown
- 1971-08-14 HU HUHO1406A patent/HU166412B/hu unknown
-
1975
- 1975-01-24 SE SE7500789A patent/SE401776B/xx unknown
-
1979
- 1979-07-13 JP JP8834479A patent/JPS559800A/ja active Pending
Also Published As
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