PL79781B1 - - Google Patents

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Publication number
PL79781B1
PL79781B1 PL1970142238A PL14223870A PL79781B1 PL 79781 B1 PL79781 B1 PL 79781B1 PL 1970142238 A PL1970142238 A PL 1970142238A PL 14223870 A PL14223870 A PL 14223870A PL 79781 B1 PL79781 B1 PL 79781B1
Authority
PL
Poland
Prior art keywords
hydrogen atom
formula
atom
methyl radical
hydrogen
Prior art date
Application number
PL1970142238A
Other languages
English (en)
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL79781B1 publication Critical patent/PL79781B1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (2)

1. Zastrzezenie patentowe 35 Sposób wytwarzania nowych 21,21-dwuchloro- pregnanów o wzorze 1, w którym RL oznacza atom wodoru lub chloru, R2 oznacza atom wodoru, atom fluoru lub rodnik metylowy, R8 oznacza atom wo¬ doru lub rodnik metylowy, R4 oznacza atom wo- 40 doru lub wolna lub zestryfikowana grupe hydro¬ ksylowa a Ci ... Cf oznacza pojedyncze lub pod¬ wójne wiazanie miedzy atomami wegla, znamien¬ ny tym, ze steroid wyjsciowy o wzorze 2, w któ¬ rym Rj R2, R3, R4 i Ci . . . C2 maja znaczenie wy- 45 zej podane, poddaje sie w rozpuszczalniku w ciagu co najmniej 3 godzin równoczesnemu dzialaniu fluorowodoru i substancji dostarczajacej dodatnio naladowanych atomów chloru.KI. 12o,"25/05 79 781 MKP C07c 169/30 CHCU Wzór 1 Wzór
2. .LV A*] |ifcA4 " Patentowego luuiv»**v' U**1! Cena 10 zl RZG — 2285/75 105 egz. A4 PL PL
PL1970142238A 1969-07-24 1970-07-23 PL79781B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1938218A DE1938218C3 (de) 1969-07-24 1969-07-24 9 a,21,21-Trichlor-ll ß-fluor- pregnene, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PL79781B1 true PL79781B1 (pl) 1975-06-30

Family

ID=5741103

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1970142238A PL79781B1 (pl) 1969-07-24 1970-07-23

Country Status (18)

Country Link
US (1) US3681405A (pl)
JP (1) JPS4815290B1 (pl)
AT (1) AT300217B (pl)
BE (1) BE753874A (pl)
CH (1) CH557339A (pl)
CS (1) CS161757B2 (pl)
DE (1) DE1938218C3 (pl)
DK (1) DK122454B (pl)
ES (1) ES381790A1 (pl)
FI (1) FI46844C (pl)
FR (1) FR2059554B1 (pl)
GB (1) GB1317194A (pl)
IE (1) IE34401B1 (pl)
IL (1) IL34976A (pl)
NL (1) NL7010876A (pl)
PL (1) PL79781B1 (pl)
SE (1) SE355578B (pl)
ZA (1) ZA704574B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
US8207151B2 (en) 2008-05-28 2012-06-26 Validus Biopharma Inc. Non-hormonal steroid modulators of NF-κB for treatment of disease
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236866A (en) * 1959-04-08 1966-02-22 Syntex Corp 21, 21-difluoro pregnenes
US3025312A (en) * 1959-07-14 1962-03-13 Olin Mathieson 9alpha, 11beta-dichloro pregnanes
US3038898A (en) * 1960-11-10 1962-06-12 Syntex Sa 6-fluoromethyl-9alpha, 11beta-dichlorocortical hormones

Also Published As

Publication number Publication date
CH557339A (de) 1974-12-31
IE34401L (en) 1971-01-24
FR2059554A1 (pl) 1971-06-04
ZA704574B (en) 1971-03-31
JPS4815290B1 (pl) 1973-05-14
FI46844C (fi) 1973-07-10
DK122454B (da) 1972-03-06
FR2059554B1 (pl) 1974-06-14
DE1938218B2 (de) 1978-01-26
NL7010876A (pl) 1971-01-26
BE753874A (fr) 1971-01-25
IL34976A (en) 1973-06-29
DE1938218C3 (de) 1978-10-19
SE355578B (pl) 1973-04-30
ES381790A1 (es) 1972-12-01
US3681405A (en) 1972-08-01
IL34976A0 (en) 1970-09-17
DE1938218A1 (de) 1971-02-04
CS161757B2 (pl) 1975-06-10
GB1317194A (en) 1973-05-16
AT300217B (de) 1972-07-25
IE34401B1 (en) 1975-04-30
FI46844B (pl) 1973-04-02

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