PL79781B1 - - Google Patents
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- Publication number
- PL79781B1 PL79781B1 PL1970142238A PL14223870A PL79781B1 PL 79781 B1 PL79781 B1 PL 79781B1 PL 1970142238 A PL1970142238 A PL 1970142238A PL 14223870 A PL14223870 A PL 14223870A PL 79781 B1 PL79781 B1 PL 79781B1
- Authority
- PL
- Poland
- Prior art keywords
- hydrogen atom
- formula
- atom
- methyl radical
- hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (2)
1. Zastrzezenie patentowe 35 Sposób wytwarzania nowych 21,21-dwuchloro- pregnanów o wzorze 1, w którym RL oznacza atom wodoru lub chloru, R2 oznacza atom wodoru, atom fluoru lub rodnik metylowy, R8 oznacza atom wo¬ doru lub rodnik metylowy, R4 oznacza atom wo- 40 doru lub wolna lub zestryfikowana grupe hydro¬ ksylowa a Ci ... Cf oznacza pojedyncze lub pod¬ wójne wiazanie miedzy atomami wegla, znamien¬ ny tym, ze steroid wyjsciowy o wzorze 2, w któ¬ rym Rj R2, R3, R4 i Ci . . . C2 maja znaczenie wy- 45 zej podane, poddaje sie w rozpuszczalniku w ciagu co najmniej 3 godzin równoczesnemu dzialaniu fluorowodoru i substancji dostarczajacej dodatnio naladowanych atomów chloru.KI. 12o,"25/05 79 781 MKP C07c 169/30 CHCU Wzór 1 Wzór
2. .LV A*] |ifcA4 " Patentowego luuiv»**v' U**1! Cena 10 zl RZG — 2285/75 105 egz. A4 PL PL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1938218A DE1938218C3 (de) | 1969-07-24 | 1969-07-24 | 9 a,21,21-Trichlor-ll ß-fluor- pregnene, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL79781B1 true PL79781B1 (pl) | 1975-06-30 |
Family
ID=5741103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1970142238A PL79781B1 (pl) | 1969-07-24 | 1970-07-23 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3681405A (pl) |
| JP (1) | JPS4815290B1 (pl) |
| AT (1) | AT300217B (pl) |
| BE (1) | BE753874A (pl) |
| CH (1) | CH557339A (pl) |
| CS (1) | CS161757B2 (pl) |
| DE (1) | DE1938218C3 (pl) |
| DK (1) | DK122454B (pl) |
| ES (1) | ES381790A1 (pl) |
| FI (1) | FI46844C (pl) |
| FR (1) | FR2059554B1 (pl) |
| GB (1) | GB1317194A (pl) |
| IE (1) | IE34401B1 (pl) |
| IL (1) | IL34976A (pl) |
| NL (1) | NL7010876A (pl) |
| PL (1) | PL79781B1 (pl) |
| SE (1) | SE355578B (pl) |
| ZA (1) | ZA704574B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5972922A (en) * | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
| KR101701404B1 (ko) * | 2008-05-28 | 2017-02-01 | 레베라겐 바이오파마 인코포레이티드 | 질환의 치료를 위한 ＮＦ-κＢ 의 비호르몬성 스테로이드 조절제 |
| WO2011127048A2 (en) | 2010-04-05 | 2011-10-13 | Validus Biopharma | NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE |
| US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
| US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236866A (en) * | 1959-04-08 | 1966-02-22 | Syntex Corp | 21, 21-difluoro pregnenes |
| US3025312A (en) * | 1959-07-14 | 1962-03-13 | Olin Mathieson | 9alpha, 11beta-dichloro pregnanes |
| US3038898A (en) * | 1960-11-10 | 1962-06-12 | Syntex Sa | 6-fluoromethyl-9alpha, 11beta-dichlorocortical hormones |
-
1969
- 1969-07-24 DE DE1938218A patent/DE1938218C3/de not_active Expired
-
1970
- 1970-06-16 FI FI701704A patent/FI46844C/fi active
- 1970-06-18 CH CH927470A patent/CH557339A/xx not_active IP Right Cessation
- 1970-06-24 DK DK327370AA patent/DK122454B/da unknown
- 1970-07-02 CS CS4621A patent/CS161757B2/cs unknown
- 1970-07-02 AT AT598070A patent/AT300217B/de not_active IP Right Cessation
- 1970-07-03 ZA ZA704574A patent/ZA704574B/xx unknown
- 1970-07-15 GB GB3432470A patent/GB1317194A/en not_active Expired
- 1970-07-15 ES ES381790A patent/ES381790A1/es not_active Expired
- 1970-07-21 IE IE948/70A patent/IE34401B1/xx unknown
- 1970-07-22 NL NL7010876A patent/NL7010876A/xx not_active Application Discontinuation
- 1970-07-22 IL IL34976A patent/IL34976A/xx unknown
- 1970-07-22 US US57334A patent/US3681405A/en not_active Expired - Lifetime
- 1970-07-23 PL PL1970142238A patent/PL79781B1/pl unknown
- 1970-07-23 JP JP45064682A patent/JPS4815290B1/ja active Pending
- 1970-07-23 FR FR707027250A patent/FR2059554B1/fr not_active Expired
- 1970-07-23 SE SE10206/70A patent/SE355578B/xx unknown
- 1970-07-24 BE BE753874D patent/BE753874A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1938218B2 (de) | 1978-01-26 |
| DK122454B (da) | 1972-03-06 |
| IE34401L (en) | 1971-01-24 |
| DE1938218A1 (de) | 1971-02-04 |
| IL34976A0 (en) | 1970-09-17 |
| NL7010876A (pl) | 1971-01-26 |
| IL34976A (en) | 1973-06-29 |
| FI46844C (fi) | 1973-07-10 |
| IE34401B1 (en) | 1975-04-30 |
| US3681405A (en) | 1972-08-01 |
| ZA704574B (en) | 1971-03-31 |
| FR2059554A1 (pl) | 1971-06-04 |
| CH557339A (de) | 1974-12-31 |
| DE1938218C3 (de) | 1978-10-19 |
| JPS4815290B1 (pl) | 1973-05-14 |
| GB1317194A (en) | 1973-05-16 |
| AT300217B (de) | 1972-07-25 |
| BE753874A (fr) | 1971-01-25 |
| FR2059554B1 (pl) | 1974-06-14 |
| SE355578B (pl) | 1973-04-30 |
| CS161757B2 (pl) | 1975-06-10 |
| ES381790A1 (es) | 1972-12-01 |
| FI46844B (pl) | 1973-04-02 |
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