PL4335517T3 - Podawanie i dawkowanie diaminofenotiazyn - Google Patents

Podawanie i dawkowanie diaminofenotiazyn

Info

Publication number
PL4335517T3
PL4335517T3 PL23212899.1T PL23212899T PL4335517T3 PL 4335517 T3 PL4335517 T3 PL 4335517T3 PL 23212899 T PL23212899 T PL 23212899T PL 4335517 T3 PL4335517 T3 PL 4335517T3
Authority
PL
Poland
Prior art keywords
diaminophenothiazines
dosage
administration
Prior art date
Application number
PL23212899.1T
Other languages
English (en)
Inventor
Claude Michel Wischik
Björn Olaf SCHELTER
Damon Jude Wischik
John Mervyn David Storey
Original Assignee
Taurx Therapeutics Management Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59399428&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL4335517(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB1612863.9A external-priority patent/GB201612863D0/en
Priority claimed from GBGB1710382.1A external-priority patent/GB201710382D0/en
Application filed by Taurx Therapeutics Management Ltd. filed Critical Taurx Therapeutics Management Ltd.
Publication of PL4335517T3 publication Critical patent/PL4335517T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • A23P10/28Tabletting; Making food bars by compression of a dry powdered mixture
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2203/00Decoration means, markings, information elements, contents indicators
    • B65D2203/02Labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Mycology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Composite Materials (AREA)
  • Mechanical Engineering (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
PL23212899.1T 2016-07-25 2017-07-25 Podawanie i dawkowanie diaminofenotiazyn PL4335517T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1612863.9A GB201612863D0 (en) 2016-07-25 2016-07-25 Administration and dosage of diaminophenothiazines
GBGB1710382.1A GB201710382D0 (en) 2017-06-29 2017-06-29 Administration and dosage of Diaminophenothiazines

Publications (1)

Publication Number Publication Date
PL4335517T3 true PL4335517T3 (pl) 2026-02-16

Family

ID=59399428

Family Applications (2)

Application Number Title Priority Date Filing Date
PL23212899.1T PL4335517T3 (pl) 2016-07-25 2017-07-25 Podawanie i dawkowanie diaminofenotiazyn
PL17743330.7T PL3487505T3 (pl) 2016-07-25 2017-07-25 Podawanie i dawkowanie diaminofenotiazyn

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL17743330.7T PL3487505T3 (pl) 2016-07-25 2017-07-25 Podawanie i dawkowanie diaminofenotiazyn

Country Status (18)

Country Link
US (5) US11065256B2 (pl)
EP (3) EP4335517B8 (pl)
JP (1) JP7073330B2 (pl)
KR (4) KR20240074909A (pl)
CN (2) CN109789148A (pl)
AU (3) AU2017301966B2 (pl)
CA (1) CA3031578C (pl)
DK (2) DK4335517T3 (pl)
ES (2) ES3046673T3 (pl)
FI (2) FI4335517T3 (pl)
HR (2) HRP20230628T1 (pl)
MX (2) MX385594B (pl)
MY (2) MY201804A (pl)
PL (2) PL4335517T3 (pl)
PT (2) PT3487505T (pl)
SG (1) SG11201900228YA (pl)
SI (2) SI3487505T1 (pl)
WO (1) WO2018019823A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2457904B1 (en) 2006-07-11 2014-11-19 Wista Laboratories Ltd. Methods of synthesis and/or purification of diaminophenothiazinium compounds
HRP20230628T1 (hr) 2016-07-25 2023-09-29 Wista Laboratories Ltd. Primjena i doziranje diaminofenotiazina
PT3826639T (pt) 2018-07-26 2024-10-09 Wista Lab Ltd Dosagem otimizada de diaminofenotiazinas em populações
WO2020048593A1 (en) 2018-09-05 2020-03-12 Wista Laboratories Ltd. Network methods for neurodegenerative diseases
MY209608A (en) * 2019-04-10 2025-07-24 Genting Taurx Diagnostic Centre Sdn Bhd Adaptive neurological testing method
GB201909493D0 (en) * 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909454D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909506D0 (en) * 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
GB202006659D0 (en) 2020-05-05 2020-06-17 Wista Lab Ltd Therapeutic treatments
JP2023524146A (ja) * 2020-05-05 2023-06-08 ウィスタ ラボラトリーズ リミテッド 低酸素血症の治療に使用されるメチルチオニニウム化合物
EP4277624B1 (en) * 2021-01-18 2026-01-14 Biohaven Therapeutics Ltd. Troriluzole for use in the treatment of alzheimer's disease of mild severity
JP2025518248A (ja) 2022-05-31 2025-06-12 ウィスタ ラボラトリーズ リミテッド メチルチオニニウム(mt)含有化合物を利用した神経変性障害の処置
CA3268316A1 (en) 2022-09-21 2024-03-28 Wista Laboratories Ltd. NEW FORMULATIONS AND VEHICLES
WO2024184146A1 (en) 2023-03-03 2024-09-12 Wista Laboratories Ltd. Diaminophenothiazine for the treatment of microvascular brain disease disease

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
GB0100119D0 (en) 2001-01-03 2001-02-14 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
GB0106953D0 (en) 2001-03-20 2001-05-09 Univ Aberdeen Neufofibrillary labels
WO2003101458A1 (en) 2002-05-31 2003-12-11 H. Lundbeck A/S A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease
EP1799662B1 (en) 2004-09-23 2013-04-17 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
EP2853293B1 (en) 2006-03-29 2017-11-22 WisTa Laboratories Ltd. Thioninium compounds and their use
JP5654748B2 (ja) * 2006-03-29 2015-01-14 ウイスタ・ラボラトリーズ・リミテッドWista Laboratories Ltd. タンパク質凝集の阻害物質
DE602007008550D1 (de) 2006-03-29 2010-09-30 Wista Lab Ltd 3,7-diamino-10h-phenothiazinsalze und ihre verwendung
EP2457904B1 (en) 2006-07-11 2014-11-19 Wista Laboratories Ltd. Methods of synthesis and/or purification of diaminophenothiazinium compounds
FR2903696B1 (fr) 2006-07-12 2011-02-11 Provence Technologies Procede de purification de composes diaminophenothiazium
WO2008155533A2 (en) * 2007-06-19 2008-12-24 Wista Laboratories Ltd Phenothiazine compounds for treating mild cognitive impairment
US9149481B2 (en) * 2007-10-03 2015-10-06 Wista Laboratories Ltd. Therapeutic use of diaminophenothiazines
WO2009060191A2 (en) 2007-11-05 2009-05-14 Wista Laboratories Ltd. Systems for clinical trials
WO2010078659A1 (en) 2009-01-12 2010-07-15 Foster Health Inc. Compositions and methods for nutritional prevention and treatment of alzheimer's-associated conditions
WO2010104375A1 (en) 2009-03-12 2010-09-16 N.V. Nutricia Stigmasterol for the treatment of alzheimer's disease
CN102666510B (zh) 2009-09-24 2016-09-14 维斯塔实验室有限公司 基本上纯净的亚甲蓝五水合物形式a的制备方法及其用途
BR122019022612B8 (pt) 2009-09-24 2021-07-27 Wista Lab Ltd forma e de mono-hidrato de cloreto de metiltionínio, seu processo de preparação, e composição farmacêutica
DE102010062810B4 (de) 2010-09-07 2014-03-13 Immungenetics Ag 2-(R2-Thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine zur Behandlung neurodegenerativer Erkrankungen ausgewählt aus beta-Amyloidopathien und alpha-Synucleinopathien
ES2655492T3 (es) 2010-11-30 2018-02-20 Wista Laboratories Ltd. Formulaciones que comprenden cloruro de metiltioninio
AU2011358840B2 (en) 2011-02-11 2017-05-04 TauRx Therapeutics Management Ltd Phenothiazine diaminium salts and their use
HRP20230628T1 (hr) 2016-07-25 2023-09-29 Wista Laboratories Ltd. Primjena i doziranje diaminofenotiazina
GB201614834D0 (en) 2016-09-01 2016-10-19 Wista Lab Ltd Treatment of dementia
PT3826639T (pt) 2018-07-26 2024-10-09 Wista Lab Ltd Dosagem otimizada de diaminofenotiazinas em populações
GB201909493D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions

Also Published As

Publication number Publication date
AU2023203084B2 (en) 2025-03-06
EP4335517A2 (en) 2024-03-13
ES2946165T3 (es) 2023-07-13
SI3487505T1 (sl) 2023-10-30
FI3487505T3 (fi) 2023-06-05
US11065256B2 (en) 2021-07-20
US20230165877A1 (en) 2023-06-01
ES3046673T3 (en) 2025-12-02
US20200016165A1 (en) 2020-01-16
EP4335517B1 (en) 2025-08-27
JP2019527216A (ja) 2019-09-26
EP4223297A3 (en) 2023-11-15
MX385594B (es) 2025-03-18
EP3487505B1 (en) 2023-05-03
SI4335517T1 (sl) 2025-11-28
AU2017301966B2 (en) 2022-09-22
KR20230003261A (ko) 2023-01-05
US12128051B2 (en) 2024-10-29
EP4335517A3 (en) 2024-08-07
JP7073330B2 (ja) 2022-05-23
MX2019000946A (es) 2019-05-13
EP4223297A2 (en) 2023-08-09
MY210565A (en) 2025-09-30
AU2022291420B2 (en) 2024-05-09
PT3487505T (pt) 2023-06-07
EP4335517B8 (en) 2025-10-22
CN109789148A (zh) 2019-05-21
KR20190031552A (ko) 2019-03-26
DK4335517T3 (da) 2025-09-29
CA3031578A1 (en) 2018-02-01
US20230346794A1 (en) 2023-11-02
FI4335517T3 (fi) 2025-10-21
KR20240074909A (ko) 2024-05-28
PL3487505T3 (pl) 2023-10-09
WO2018019823A8 (en) 2018-04-05
DK3487505T3 (da) 2023-05-30
AU2022291420A1 (en) 2023-02-02
KR102475825B1 (ko) 2022-12-08
US20250262219A1 (en) 2025-08-21
HRP20230628T1 (hr) 2023-09-29
CN116531386A (zh) 2023-08-04
MX2021009899A (es) 2021-09-14
EP3487505A1 (en) 2019-05-29
AU2017301966A1 (en) 2019-03-07
MY201804A (en) 2024-03-19
WO2018019823A1 (en) 2018-02-01
US20220008431A1 (en) 2022-01-13
US12310973B2 (en) 2025-05-27
HRP20251365T1 (hr) 2025-12-19
CA3031578C (en) 2025-07-08
US11759469B2 (en) 2023-09-19
KR102592614B1 (ko) 2023-10-24
SG11201900228YA (en) 2019-02-27
AU2023203084A1 (en) 2023-06-08
KR20230058533A (ko) 2023-05-03
PT4335517T (pt) 2025-10-07

Similar Documents

Publication Publication Date Title
NL301322I2 (nl) Repotrectinib en/of farmaceutisch aanvaardbare zouten daarvan
PL4335517T3 (pl) Podawanie i dawkowanie diaminofenotiazyn
IL258931A (en) Therapeutic compounds and methods
EP3709912A4 (en) DRUG DELIVERY SYSTEMS AND METHODS
IL256652A (en) Therapeutic compositions, combinations, and methods of use
EP3558424A4 (en) DRUG DELIVERY SYSTEMS AND METHODS
EP3463228A4 (en) INTRAOCULAR DELIVERY
PL3362084T3 (pl) Urządzenia do podawania dojelitowego i powiązane sposoby zastosowania
HUE047477T2 (hu) Palbociclib szilárd dózisformái
EP3352757C0 (en) ADMINISTRATION OF DEUTERIUM-MODIFIED CFTR POTENTIATION AGENTS
EP3302442C0 (en) DOSAGE FORMS AND THEIR USE
LT3426285T (lt) Pegilintos urikazės kompozicijos ir dozės
LT2986304T (lt) Farmacinė kompozicija, gydymo būdai ir jų panaudojimas
DK3244948T3 (da) Bestemmelse af medikamentdosis
DK3278803T3 (da) Fast farmaceutisk doseringsform af PARP-inhibitor, og anvendelse af fast farmaceutisk doseringsform af PARP-inhibitor
IL252172A0 (en) Expandable drug delivery devices and method of use
EP3681479A4 (en) METHOD OF ADMINISTRATION AND TREATMENT
DK3519018T3 (da) Medikamentadministrationsanordning
DK3400045T3 (da) Medikamentadministrationsanordning
DK3380139T3 (da) Medikamentadministrationsanordning
DK3496783T3 (da) Medikamentadministrationsanordning
EP3310376A4 (en) MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
DK3558438T3 (da) Lægemiddelindgivelsesanordning
EP3731832A4 (en) CANNABINOID DOSAGE FORM
IL282157A (en) Compounds and therapeutic uses thereof