PL4204570T3 - Sposób wytwarzania rekombinownego białka w komórce gospodarza z zablokowanym metabolizmem ramnozy oraz wektory ekspresyjne, komórki gospodarza i ich rekombinowane białka - Google Patents
Sposób wytwarzania rekombinownego białka w komórce gospodarza z zablokowanym metabolizmem ramnozy oraz wektory ekspresyjne, komórki gospodarza i ich rekombinowane białkaInfo
- Publication number
- PL4204570T3 PL4204570T3 PL21790425.9T PL21790425T PL4204570T3 PL 4204570 T3 PL4204570 T3 PL 4204570T3 PL 21790425 T PL21790425 T PL 21790425T PL 4204570 T3 PL4204570 T3 PL 4204570T3
- Authority
- PL
- Poland
- Prior art keywords
- disabled
- producing
- well
- expression vectors
- host cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20201096.3A EP3981879A1 (en) | 2020-10-09 | 2020-10-09 | Method of producing a recombinant protein in a host cell which has a disabled rhamnose metabolism as well as expression vectors, host cells and recombinant proteins thereof |
| PCT/EP2021/077820 WO2022074182A1 (en) | 2020-10-09 | 2021-10-08 | Method of producing a recombinant protein in a host cell which has a disabled rhamnose metabolism as well as expression vectors, host cells and recombinant proteins thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4204570T3 true PL4204570T3 (pl) | 2025-10-06 |
Family
ID=72826766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21790425.9T PL4204570T3 (pl) | 2020-10-09 | 2021-10-08 | Sposób wytwarzania rekombinownego białka w komórce gospodarza z zablokowanym metabolizmem ramnozy oraz wektory ekspresyjne, komórki gospodarza i ich rekombinowane białka |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20230340096A1 (pl) |
| EP (2) | EP3981879A1 (pl) |
| JP (1) | JP2023549432A (pl) |
| KR (1) | KR20230079228A (pl) |
| CN (1) | CN116323950A (pl) |
| AU (1) | AU2021357360A1 (pl) |
| CA (1) | CA3193217A1 (pl) |
| ES (1) | ES3036687T3 (pl) |
| GE (2) | GEP20247669B (pl) |
| IL (1) | IL301642A (pl) |
| MX (1) | MX2023003819A (pl) |
| PL (1) | PL4204570T3 (pl) |
| WO (1) | WO2022074182A1 (pl) |
| ZA (1) | ZA202303775B (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240099199A (ko) * | 2021-09-24 | 2024-06-28 | 엑스브레인 바이오파마 에이비 | 재조합 단백질을 발현시키기 위한 dna 구조체 및 숙주 세포 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8293503B2 (en) * | 2003-10-03 | 2012-10-23 | Promega Corporation | Vectors for directional cloning |
| CN101090969B (zh) * | 2004-12-07 | 2013-01-16 | 隆萨股份公司 | 鼠李糖启动子表达系统及用途 |
| EP2268818B1 (en) | 2008-02-29 | 2012-02-08 | Xbrane Bioscience Aktiebolag | Expression system for proteins |
| EP2362896A2 (en) * | 2008-11-11 | 2011-09-07 | Danisco US Inc. | Bacillus subtilisin comprising one or more combinable mutations |
| WO2012041899A1 (en) * | 2010-09-28 | 2012-04-05 | Xbrane Bioscience Ab | Fusion protein for secretory protein expression |
| BR112019023795A2 (pt) * | 2017-05-19 | 2020-07-28 | Council Of Scientific & Industrial Research | método para produzir ranibizumabe humanizado recombinante redobrado |
-
2020
- 2020-10-09 EP EP20201096.3A patent/EP3981879A1/en not_active Withdrawn
-
2021
- 2021-10-08 PL PL21790425.9T patent/PL4204570T3/pl unknown
- 2021-10-08 US US18/028,883 patent/US20230340096A1/en active Pending
- 2021-10-08 GE GEAP202116228A patent/GEP20247669B/en unknown
- 2021-10-08 CA CA3193217A patent/CA3193217A1/en active Pending
- 2021-10-08 CN CN202180069464.6A patent/CN116323950A/zh active Pending
- 2021-10-08 WO PCT/EP2021/077820 patent/WO2022074182A1/en not_active Ceased
- 2021-10-08 AU AU2021357360A patent/AU2021357360A1/en active Pending
- 2021-10-08 EP EP21790425.9A patent/EP4204570B1/en active Active
- 2021-10-08 GE GEAP202416228A patent/GEAP202416228A/en unknown
- 2021-10-08 ES ES21790425T patent/ES3036687T3/es active Active
- 2021-10-08 IL IL301642A patent/IL301642A/en unknown
- 2021-10-08 MX MX2023003819A patent/MX2023003819A/es unknown
- 2021-10-08 JP JP2023546386A patent/JP2023549432A/ja active Pending
- 2021-10-08 KR KR1020237015497A patent/KR20230079228A/ko active Pending
-
2023
- 2023-03-23 ZA ZA2023/03775A patent/ZA202303775B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4204570C0 (en) | 2025-06-04 |
| ZA202303775B (en) | 2025-07-30 |
| AU2021357360A1 (en) | 2023-05-04 |
| CN116323950A (zh) | 2023-06-23 |
| KR20230079228A (ko) | 2023-06-05 |
| MX2023003819A (es) | 2023-08-16 |
| EP4204570B1 (en) | 2025-06-04 |
| JP2023549432A (ja) | 2023-11-24 |
| CA3193217A1 (en) | 2022-04-14 |
| EP3981879A1 (en) | 2022-04-13 |
| GEP20247669B (en) | 2024-09-25 |
| IL301642A (en) | 2023-05-01 |
| US20230340096A1 (en) | 2023-10-26 |
| AU2021357360A9 (en) | 2023-07-06 |
| ES3036687T3 (en) | 2025-09-23 |
| WO2022074182A9 (en) | 2022-06-16 |
| EP4204570A1 (en) | 2023-07-05 |
| WO2022074182A1 (en) | 2022-04-14 |
| GEAP202416228A (en) | 2024-05-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1513937T3 (da) | Fremgangsmåde til den samtidige produktion af multiple proteiner; vektorer og celler til anvendelse derved | |
| WO2006042158A3 (en) | Methods and compositions for improving recombinant protein production | |
| SG162834A1 (en) | Refolding of recombinant proteins | |
| WO2005061716A3 (de) | Expressionsvektor zur antibiotikafreien expression | |
| MX2011008094A (es) | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. | |
| JP2014524241A5 (pl) | ||
| IN2012DN03823A (pl) | ||
| WO2008104890A3 (en) | Compositions and methods for producing apolipoprotein | |
| EP2351834A3 (en) | Production of biologically active proteins | |
| WO2010132341A3 (en) | Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein | |
| PL4204570T3 (pl) | Sposób wytwarzania rekombinownego białka w komórce gospodarza z zablokowanym metabolizmem ramnozy oraz wektory ekspresyjne, komórki gospodarza i ich rekombinowane białka | |
| WO2014097113A3 (en) | Production of therapeutic proteins in genetically modified mammalian cells | |
| NO20052276L (no) | Sirkulaert DNA-molekyl med en kondisjonell replikasjonsorigo, fremgangsmate for deres fremstilling og deres anvendelse i genterapi | |
| DK2431470T3 (da) | DNase expression i rekombinante værtsceller | |
| IL175021A0 (en) | Chromatin insulator, its preparation and use in protein expression | |
| Niimi et al. | Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole | |
| EP1930428A4 (en) | HEFEWIRT, TRANSFORMANTE AND PROCESS FOR PREPARING FOREIGN PROTEIN | |
| WO2004053137A3 (en) | Method for protein production | |
| EP2189529A4 (en) | RECOMBINANT MAMMALIAN CELLS, PROCESS FOR PRODUCING RECOMBINANT MAMMALIAN CELLS, AND METHOD FOR PRODUCING TARGET PROTEIN | |
| WO2012122378A3 (en) | Antibody-like proteins for therapeutic and diagnostic use | |
| EP2644616A8 (en) | Method for producing web protein, a fused protein, recombinant dna, an expression vector, a host cell and strain-producers | |
| ATE483026T1 (de) | Nukleinsäurekonstruct, expressionsvektor und verfahren zur steigerung der hergestellten menge von rekombinantem eiweiss | |
| MX349285B (es) | Co-expresion recombinante de reductasa de epoxido de vitamina k subunidad 1 para mejorar la expresion de proteina dependiente de vitamina k. | |
| SG11202106713UA (en) | Methods of producing multimeric proteins in eukaryotic host cells | |
| TW200600581A (en) | Nucleic acid construct and expression vector for enhancing the production of recombinant protein, and method for the massive production of recombinant protein |