PL3915989T3 - Inhibitor jak i sposób jego otrzymywania - Google Patents

Inhibitor jak i sposób jego otrzymywania

Info

Publication number
PL3915989T3
PL3915989T3 PL19913097.2T PL19913097T PL3915989T3 PL 3915989 T3 PL3915989 T3 PL 3915989T3 PL 19913097 T PL19913097 T PL 19913097T PL 3915989 T3 PL3915989 T3 PL 3915989T3
Authority
PL
Poland
Prior art keywords
preparation
method therefor
jak inhibitor
jak
inhibitor
Prior art date
Application number
PL19913097.2T
Other languages
English (en)
Inventor
Tingting Lu
Original Assignee
Felicamed Biotechnology Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Felicamed Biotechnology Co., Ltd filed Critical Felicamed Biotechnology Co., Ltd
Publication of PL3915989T3 publication Critical patent/PL3915989T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL19913097.2T 2019-01-30 2019-12-23 Inhibitor jak i sposób jego otrzymywania PL3915989T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910088713 2019-01-30
PCT/CN2019/127494 WO2020155931A1 (zh) 2019-01-30 2019-12-23 一种jak抑制剂及其制备方法

Publications (1)

Publication Number Publication Date
PL3915989T3 true PL3915989T3 (pl) 2023-12-11

Family

ID=71839941

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19913097.2T PL3915989T3 (pl) 2019-01-30 2019-12-23 Inhibitor jak i sposób jego otrzymywania

Country Status (16)

Country Link
US (1) US20220106319A1 (pl)
EP (1) EP3915989B1 (pl)
JP (1) JP7278649B6 (pl)
KR (1) KR20210120074A (pl)
CN (1) CN111499641B (pl)
AU (1) AU2019426113B2 (pl)
BR (1) BR112021014525A8 (pl)
CA (1) CA3127892A1 (pl)
CO (1) CO2021010415A2 (pl)
DK (1) DK3915989T3 (pl)
ES (1) ES2958160T3 (pl)
FI (1) FI3915989T3 (pl)
MX (1) MX2021008984A (pl)
PL (1) PL3915989T3 (pl)
PT (1) PT3915989T (pl)
WO (1) WO2020155931A1 (pl)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2288610T3 (en) * 2008-03-11 2016-11-28 Incyte Holdings Corp Azetidinesulfonic AND CYCLOBUTANDERIVATER AS JAK INHIBITORS
PT2384326E (pt) 2008-08-20 2014-06-09 Zoetis Llc Compostos de pirrolo[2,3-d]pirimidina
JP5629324B2 (ja) * 2009-10-15 2014-11-19 ファイザー・インク ピロロ[2,3−d]ピリミジン化合物
JP5739446B2 (ja) 2009-12-18 2015-06-24 ファイザー・インク ピロロ[2,3−d]ピリミジン化合物
WO2011078143A1 (ja) * 2009-12-22 2011-06-30 塩野義製薬株式会社 ピリミジン誘導体およびそれらを含有する医薬組成物
WO2014015107A1 (en) 2012-07-20 2014-01-23 Zoetis Llc Dosing regimen for janus kinase (jak) inhibitors
JP6145179B2 (ja) * 2013-02-22 2017-06-07 ファイザー・インク ヤヌス関連キナーゼ(JAK)の阻害剤としてのピロロ[2,3−d]ピリミジン誘導体
WO2014146249A1 (en) 2013-03-19 2014-09-25 Merck Sharp & Dohme Corp. Geminally substituted cyanoethylpyrazolo pyridones as janus kinase inhibitors
WO2014146246A1 (en) 2013-03-19 2014-09-25 Merck Sharp & Dohme Corp. Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors
CN105189508B (zh) * 2013-03-19 2018-11-23 默沙东公司 作为janus激酶抑制剂的环烷基腈吡唑并吡啶酮
MX2017013797A (es) * 2015-05-29 2018-03-21 Wuxi Fortune Pharmaceutical Co Ltd Inhibidor de janus quinasa.
NZ744341A (en) * 2016-02-16 2019-06-28 Zoetis Services Llc Process for preparing 7h-pyrrolo [2, 3-d] pyrimidine compounds
US11524961B2 (en) * 2017-01-23 2022-12-13 Shanghai Longwood Biopharmaceuticals Co., Ltd. JAK kinase inhibitor and preparation method and use thereof
PL3601253T3 (pl) * 2017-03-28 2022-01-17 Bayer Aktiengesellschaft Nowe hamujące ptefb związki makrocykliczne

Also Published As

Publication number Publication date
BR112021014525A8 (pt) 2022-11-22
EP3915989B1 (en) 2023-06-28
MX2021008984A (es) 2021-09-08
FI3915989T3 (fi) 2023-09-20
WO2020155931A1 (zh) 2020-08-06
DK3915989T3 (da) 2023-09-18
CN111499641B (zh) 2021-06-04
AU2019426113B2 (en) 2022-06-16
JP7278649B6 (ja) 2024-02-15
EP3915989A4 (en) 2022-03-09
CO2021010415A2 (es) 2021-08-19
EP3915989A1 (en) 2021-12-01
JP2022518821A (ja) 2022-03-16
AU2019426113A1 (en) 2021-09-09
JP7278649B2 (ja) 2023-05-22
CN111499641A (zh) 2020-08-07
ES2958160T3 (es) 2024-02-02
CA3127892A1 (en) 2020-08-06
BR112021014525A2 (pt) 2021-09-28
KR20210120074A (ko) 2021-10-06
US20220106319A1 (en) 2022-04-07
PT3915989T (pt) 2023-10-02

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