PL388752A1 - Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D - Google Patents

Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D

Info

Publication number
PL388752A1
PL388752A1 PL388752A PL38875209A PL388752A1 PL 388752 A1 PL388752 A1 PL 388752A1 PL 388752 A PL388752 A PL 388752A PL 38875209 A PL38875209 A PL 38875209A PL 388752 A1 PL388752 A1 PL 388752A1
Authority
PL
Poland
Prior art keywords
vitamin
derivatives
preparation
application
synthons
Prior art date
Application number
PL388752A
Other languages
English (en)
Other versions
PL216135B1 (pl
Inventor
Michał Chodyński
Małgorzata Krupa
Krzysztof Krajewski
Marek Kubiszewski
Andrzej Kutner
Anita Pietraszek
Kinga Trzcińska
Original Assignee
Instytut Farmaceutyczny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Farmaceutyczny filed Critical Instytut Farmaceutyczny
Priority to PL388752A priority Critical patent/PL216135B1/pl
Priority to PCT/PL2010/000069 priority patent/WO2011016739A2/en
Priority to EP10754805A priority patent/EP2462113A2/en
Priority to US13/389,291 priority patent/US20130006003A1/en
Publication of PL388752A1 publication Critical patent/PL388752A1/pl
Publication of PL216135B1 publication Critical patent/PL216135B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem wynalazku jest synton przedstawiony wzorem (I), w którym R1 i R2 są takie same lub różne i niezależnie oznaczają atom wodoru lub grupę zabezpieczającą funkcję hydroksylową i jego zastosowanie do syntezy pochodnych 19-nor witamin D.
PL388752A 2009-08-07 2009-08-07 Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D PL216135B1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL388752A PL216135B1 (pl) 2009-08-07 2009-08-07 Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D
PCT/PL2010/000069 WO2011016739A2 (en) 2009-08-07 2010-08-07 New synthones for preparation of 19-nor vitamin d derivatives
EP10754805A EP2462113A2 (en) 2009-08-07 2010-08-07 New synthones for preparation of 19-nor vitamin d derivatives
US13/389,291 US20130006003A1 (en) 2009-08-07 2010-08-07 New synthones for preparation of 19-nor vitamin d derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL388752A PL216135B1 (pl) 2009-08-07 2009-08-07 Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D

Publications (2)

Publication Number Publication Date
PL388752A1 true PL388752A1 (pl) 2011-02-14
PL216135B1 PL216135B1 (pl) 2014-03-31

Family

ID=43544815

Family Applications (1)

Application Number Title Priority Date Filing Date
PL388752A PL216135B1 (pl) 2009-08-07 2009-08-07 Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D

Country Status (4)

Country Link
US (1) US20130006003A1 (pl)
EP (1) EP2462113A2 (pl)
PL (1) PL216135B1 (pl)
WO (1) WO2011016739A2 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105348163B (zh) * 2014-08-18 2017-06-16 武汉启瑞药业有限公司 维生素d类似物及其制备方法和医药用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
NZ232734A (en) 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5086191A (en) 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
AU666563B2 (en) 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
PL188697B1 (pl) 1998-01-14 2005-03-31 Inst Farmaceutyczny Sposób otrzymywania pochodnych cholekalcyferolu oraz nowe związki pośrednie
IL139354A (en) * 1998-05-29 2005-08-31 Bone Care Internat Inc Method for making hydroxy-25 ene-vitamin d compounds
AU2003292920A1 (en) * 2002-12-18 2004-07-09 Cytochroma Inc. 25-so2-substituted analogs of 1alpha, 25-dihydroxyvitamin d3 (calcitriol)
US7232810B2 (en) * 2003-08-20 2007-06-19 Wisconsin Alumni Research Foundation 2-methylene-19-nor-vitamin D2 compounds
US7491712B1 (en) * 2007-12-10 2009-02-17 Formosa Laboratories, Inc. Process for preparation of paricalcitol and intermediates thereof

Also Published As

Publication number Publication date
EP2462113A2 (en) 2012-06-13
PL216135B1 (pl) 2014-03-31
US20130006003A1 (en) 2013-01-03
WO2011016739A2 (en) 2011-02-10
WO2011016739A3 (en) 2011-05-12

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