PL3878444T3 - (n-(2-((2-benzylofenylo)amino)-2-oksoetylo)-l-naftoamid) jako przeciwnowotworowy środek terapeutyczny - Google Patents

(n-(2-((2-benzylofenylo)amino)-2-oksoetylo)-l-naftoamid) jako przeciwnowotworowy środek terapeutyczny

Info

Publication number
PL3878444T3
PL3878444T3 PL20216249.1T PL20216249T PL3878444T3 PL 3878444 T3 PL3878444 T3 PL 3878444T3 PL 20216249 T PL20216249 T PL 20216249T PL 3878444 T3 PL3878444 T3 PL 3878444T3
Authority
PL
Poland
Prior art keywords
naphthamide
benzylphenyl
oxoethyl
amino
therapeutic agent
Prior art date
Application number
PL20216249.1T
Other languages
English (en)
Inventor
Robert J. Hickey
Linda H. Malkas
Original Assignee
Rll, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rll, Llc filed Critical Rll, Llc
Publication of PL3878444T3 publication Critical patent/PL3878444T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL20216249.1T 2015-04-10 2016-04-08 (n-(2-((2-benzylofenylo)amino)-2-oksoetylo)-l-naftoamid) jako przeciwnowotworowy środek terapeutyczny PL3878444T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14/684,259 US10420840B2 (en) 2015-04-10 2015-04-10 Anticancer therapeutic agents

Publications (1)

Publication Number Publication Date
PL3878444T3 true PL3878444T3 (pl) 2025-01-07

Family

ID=57072079

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20216249.1T PL3878444T3 (pl) 2015-04-10 2016-04-08 (n-(2-((2-benzylofenylo)amino)-2-oksoetylo)-l-naftoamid) jako przeciwnowotworowy środek terapeutyczny
PL16777344T PL3280261T3 (pl) 2015-04-10 2016-04-08 Przeciwnowotworowe środki terapeutyczne

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16777344T PL3280261T3 (pl) 2015-04-10 2016-04-08 Przeciwnowotworowe środki terapeutyczne

Country Status (12)

Country Link
US (1) US10420840B2 (pl)
EP (2) EP3280261B1 (pl)
JP (1) JP6748704B2 (pl)
CN (1) CN107404876B (pl)
AU (1) AU2016245886B2 (pl)
BR (1) BR122023024844A2 (pl)
CA (1) CA2978965C (pl)
ES (1) ES2991018T3 (pl)
FI (1) FI3878444T3 (pl)
PL (2) PL3878444T3 (pl)
PT (1) PT3878444T (pl)
WO (1) WO2016164707A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023231620A1 (en) * 2022-03-07 2024-09-12 City Of Hope Pcna inhibitors and uses thereof
WO2025054318A1 (en) * 2023-09-06 2025-03-13 City Of Hope Pcna inhibitors and uses thereof
WO2025184571A1 (en) * 2024-03-01 2025-09-04 City Of Hope Pcna inhibitors for the treatment of myc family associated cancers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627165A (en) 1990-06-13 1997-05-06 Drug Innovation & Design, Inc. Phosphorous prodrugs and therapeutic delivery systems using same
US20050037090A1 (en) 1998-12-23 2005-02-17 Mckearn John P. Combination therapy including a cyclooxygenase-2 inhibitor and an antineoplastic agent
WO2006116631A2 (en) 2005-04-27 2006-11-02 Indiana University Research And Technology Corporation Cancer specific pcna isoform binding antibodies and uses thereof
AU2006261856B2 (en) * 2005-06-27 2012-07-05 Indiana University Research And Technology Corporation csPCNA isoform modifications and uses thereof
EP1989225A2 (en) * 2006-02-17 2008-11-12 Indiana University Research and Technology Corporation Peptide based inhibition of capcna protein-protein interactions in cancer
US20090123487A1 (en) 2007-09-19 2009-05-14 Katia Rothhaar Precursors and enzymes associated with post translational modification of proteins implicated in isoform generation of PCNA
CA2709398C (en) 2007-12-14 2017-11-07 The Cleveland Clinic Foundation Use of stromal cell-derived factor 1 for promoting wound healing
GB0808282D0 (en) 2008-05-07 2008-06-11 Medical Res Council Compounds for use in stabilizing p53 mutants
WO2010011890A2 (en) * 2008-07-24 2010-01-28 Indiana University Research And Technology Corporation Cancer peptide therapeutics
US20120195978A1 (en) * 2009-10-07 2012-08-02 Indiana University Research And Technology Corpora Capcna peptide therapeutics for cancer
JP2014511839A (ja) * 2011-03-23 2014-05-19 インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレイション 抗癌治療薬
MX2021006326A (es) * 2015-09-17 2022-12-16 Inhibidores de pcna.

Also Published As

Publication number Publication date
AU2016245886A1 (en) 2017-10-12
EP3280261A1 (en) 2018-02-14
CA2978965A1 (en) 2016-10-13
EP3878444A1 (en) 2021-09-15
CN107404876B (zh) 2023-04-14
US10420840B2 (en) 2019-09-24
US20160296482A1 (en) 2016-10-13
AU2016245886B2 (en) 2020-04-30
CA2978965C (en) 2023-11-14
FI3878444T3 (fi) 2024-11-19
JP6748704B2 (ja) 2020-09-02
CN107404876A (zh) 2017-11-28
PT3878444T (pt) 2024-11-08
EP3280261B1 (en) 2020-12-23
BR112017019983A2 (pt) 2018-06-19
PL3280261T3 (pl) 2021-09-06
BR122023024844A2 (pt) 2024-01-23
WO2016164707A1 (en) 2016-10-13
EP3280261A4 (en) 2018-12-12
ES2991018T3 (es) 2024-12-02
JP2018510917A (ja) 2018-04-19
EP3878444B1 (en) 2024-10-09

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