BR112017019983A2 - agentes terapêuticos anticâncer - Google Patents

agentes terapêuticos anticâncer

Info

Publication number
BR112017019983A2
BR112017019983A2 BR112017019983A BR112017019983A BR112017019983A2 BR 112017019983 A2 BR112017019983 A2 BR 112017019983A2 BR 112017019983 A BR112017019983 A BR 112017019983A BR 112017019983 A BR112017019983 A BR 112017019983A BR 112017019983 A2 BR112017019983 A2 BR 112017019983A2
Authority
BR
Brazil
Prior art keywords
therapeutic agents
anticancer therapeutic
cytotoxicity
agents
cancer
Prior art date
Application number
BR112017019983A
Other languages
English (en)
Other versions
BR112017019983B1 (pt
Inventor
H Malkas Linda
J Hickey Robert
Original Assignee
Rll Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rll Llc filed Critical Rll Llc
Priority to BR122023024844-9A priority Critical patent/BR122023024844A2/pt
Publication of BR112017019983A2 publication Critical patent/BR112017019983A2/pt
Publication of BR112017019983B1 publication Critical patent/BR112017019983B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

a presente invenção se refere a agentes terapêuticos anticâncer que exibem citotoxicidade preferencial a células malignas que expressam uma isoforma específica para câncer do antígeno nuclear de célula proliferante (capcna) em comparação à citotoxicidade a células não malignas comparáveis, a composições farmacêuticas que compreendem os agentes e a seu uso na terapia de câncer.
BR112017019983-1A 2015-04-10 2016-04-08 Agentes terapêuticos anticâncer BR112017019983B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122023024844-9A BR122023024844A2 (pt) 2015-04-10 2016-04-08 Agentes terapêuticos anticâncer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/684,259 2015-04-10
US14/684,259 US10420840B2 (en) 2015-04-10 2015-04-10 Anticancer therapeutic agents
PCT/US2016/026619 WO2016164707A1 (en) 2015-04-10 2016-04-08 Anticancer therapeutic agents

Publications (2)

Publication Number Publication Date
BR112017019983A2 true BR112017019983A2 (pt) 2018-06-19
BR112017019983B1 BR112017019983B1 (pt) 2024-03-26

Family

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Also Published As

Publication number Publication date
PL3280261T3 (pl) 2021-09-06
JP2018510917A (ja) 2018-04-19
EP3878444A1 (en) 2021-09-15
EP3280261A4 (en) 2018-12-12
CA2978965C (en) 2023-11-14
AU2016245886A1 (en) 2017-10-12
US20160296482A1 (en) 2016-10-13
EP3280261A1 (en) 2018-02-14
BR122023024844A2 (pt) 2024-01-23
EP3280261B1 (en) 2020-12-23
WO2016164707A1 (en) 2016-10-13
CA2978965A1 (en) 2016-10-13
CN107404876B (zh) 2023-04-14
US10420840B2 (en) 2019-09-24
JP6748704B2 (ja) 2020-09-02
CN107404876A (zh) 2017-11-28
AU2016245886B2 (en) 2020-04-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A01N 47/10 , A61K 31/27

Ipc: A61K 31/167 (2006.01), A61K 31/27 (2006.01), A61K

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023024844-9 PROTOCOLO 870230104304 EM 27/11/2023 22:08.

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/04/2016, OBSERVADAS AS CONDICOES LEGAIS