PL3833358T3 - Zastosowanie ligandów agonistycznych receptora igf-2 w leczeniu zespołu angelmana i autyzmu - Google Patents

Zastosowanie ligandów agonistycznych receptora igf-2 w leczeniu zespołu angelmana i autyzmu

Info

Publication number
PL3833358T3
PL3833358T3 PL19846073.5T PL19846073T PL3833358T3 PL 3833358 T3 PL3833358 T3 PL 3833358T3 PL 19846073 T PL19846073 T PL 19846073T PL 3833358 T3 PL3833358 T3 PL 3833358T3
Authority
PL
Poland
Prior art keywords
autism
igf
treatment
receptor agonist
angelman syndrome
Prior art date
Application number
PL19846073.5T
Other languages
English (en)
Inventor
Cristina Maria Alberini
Dirk Trauner
Christopher James Arp
Original Assignee
New York University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University filed Critical New York University
Publication of PL3833358T3 publication Critical patent/PL3833358T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024Esters of saccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL19846073.5T 2018-08-10 2019-08-12 Zastosowanie ligandów agonistycznych receptora igf-2 w leczeniu zespołu angelmana i autyzmu PL3833358T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862717372P 2018-08-10 2018-08-10
PCT/US2019/046227 WO2020033971A1 (en) 2018-08-10 2019-08-12 Use of igf-2 receptor agonist ligands for treatment of angelman syndrome and autism

Publications (1)

Publication Number Publication Date
PL3833358T3 true PL3833358T3 (pl) 2024-03-04

Family

ID=69415274

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19846073.5T PL3833358T3 (pl) 2018-08-10 2019-08-12 Zastosowanie ligandów agonistycznych receptora igf-2 w leczeniu zespołu angelmana i autyzmu

Country Status (12)

Country Link
US (2) US12083139B2 (pl)
EP (2) EP4356964A3 (pl)
JP (2) JP7466927B2 (pl)
KR (1) KR20210075068A (pl)
CN (1) CN113164501B (pl)
AU (1) AU2019319296B2 (pl)
BR (1) BR112021002456A2 (pl)
CA (1) CA3109137A1 (pl)
ES (1) ES2966930T3 (pl)
MX (2) MX2021001595A (pl)
PL (1) PL3833358T3 (pl)
WO (1) WO2020033971A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021001596A (es) 2018-08-10 2021-06-08 Univ New York Uso de manosa-6-fosfato y sus modificaciones para mejorar la memoria y reducir el daño mental.
US20230145514A1 (en) * 2020-04-24 2023-05-11 New York University Use of igf-2 for treatment of epileptic seizures
US12178853B2 (en) * 2020-10-13 2024-12-31 Betavive Ltd. Method and compounds for treating diabetes and associated metabolic diseases
US12447198B2 (en) 2021-10-12 2025-10-21 Betavive Ltd. Peptides and fragments for treating diabetes and associated metabolic diseases

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE139699T1 (de) 1988-08-19 1996-07-15 Univ Australian Auf phosphozucker basierende antientzündliche und/oder immunitätsunterdrückende arzneimittel
GB9516012D0 (en) 1995-08-04 1995-10-04 Univ Manchester Pharmaceutical composition
US6093388A (en) * 1996-08-12 2000-07-25 Btg International Limited Mannose-6-phosphate composition and its use in treating fibrotic disorders
AUPO309896A0 (en) * 1996-10-18 1996-11-14 Australian National University, The Novel phosphosugars and phosphosugar-containing compounds having anti-inflammatory activity
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US7666843B2 (en) 2002-09-27 2010-02-23 Children's Medical Center Corporation Methods and compositions for treatment of neurological disorder
CN1660125A (zh) 2004-12-16 2005-08-31 南开大学 大豆异黄酮增强和改善记忆的新性能及其应用
GB0516722D0 (en) * 2005-08-15 2005-09-21 Cancer Rec Tech Ltd Methods and materials
PL2019683T5 (pl) 2006-04-25 2022-12-05 The Regents Of The University Of California Podawanie czynników wzrostu do leczenia zaburzeń OUN
US20100081613A1 (en) 2006-10-11 2010-04-01 The Trustees Of Columbia University In The City Of New York Methods and compositions for enhancing memory
AR064464A1 (es) * 2006-12-22 2009-04-01 Genentech Inc Anticuerpos anti - receptor del factor de crecimiento insulinico
FR2930942B1 (fr) * 2008-05-07 2011-03-04 Centre Nat Rech Scient Nouvelles utilisations de derives de d-mannopyranose activateurs de l'angiogenese
EP2424542A4 (en) * 2009-04-28 2012-12-19 Pharmaxis Ltd PHOSPHOTETRAHYDROPYRAN COMPOUNDS FOR THE TREATMENT OF WOUNDS AND FIBROTIC ILLNESSES
WO2011000958A1 (en) * 2009-07-03 2011-01-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Compounds targeting the cation-independent mannose 6-phosphate receptor
GB0916332D0 (en) 2009-09-17 2009-10-28 Renovo Ltd Medicaments
US20120266263A1 (en) 2009-10-14 2012-10-18 Mount Sinai School Of Medicine Method of treating memory disorders and enhancing memory using igf-ii compounds
WO2011127194A1 (en) * 2010-04-06 2011-10-13 The George Washington University Compositions and methods for identifying autism spectrum disorders
WO2013119964A2 (en) * 2012-02-08 2013-08-15 Stem Centrx, Inc. Identification and enrichment of cell subpopulations
EP2928300A4 (en) * 2012-11-28 2016-07-13 Neuren Pharmaceuticals Ltd TREATMENT OF AUTISTIC DISEASES WITH GLYCYL-L-2-METHYLPROLYL-L-GLUTAMINE ACID
US20150224164A1 (en) * 2013-11-26 2015-08-13 Neuren Pharmaceuticals Limited Treatment of autism spectrum disorders using glycyl-l-2-methylprolyl-l-glumatic acid
EP3377065B1 (en) 2015-11-17 2022-05-18 Merck Sharp & Dohme Corp. Spirocyclic pyridotriazine derivatives useful as hiv integrase inhibitors
MX2021001596A (es) 2018-08-10 2021-06-08 Univ New York Uso de manosa-6-fosfato y sus modificaciones para mejorar la memoria y reducir el daño mental.

Also Published As

Publication number Publication date
ES2966930T3 (es) 2024-04-25
EP4356964A2 (en) 2024-04-24
US12083139B2 (en) 2024-09-10
EP3833358A1 (en) 2021-06-16
MX2023014556A (es) 2023-12-14
EP3833358A4 (en) 2022-04-13
CN113164501B (zh) 2024-08-09
EP4356964A3 (en) 2024-06-19
US20210315914A1 (en) 2021-10-14
AU2019319296A1 (en) 2021-03-25
KR20210075068A (ko) 2021-06-22
US20240390405A1 (en) 2024-11-28
CA3109137A1 (en) 2020-02-13
JP7466927B2 (ja) 2024-04-15
JP2024081724A (ja) 2024-06-18
WO2020033971A1 (en) 2020-02-13
AU2019319296B2 (en) 2024-09-12
EP3833358B1 (en) 2023-12-06
JP2021534125A (ja) 2021-12-09
BR112021002456A2 (pt) 2021-05-04
MX2021001595A (es) 2021-06-08
CN113164501A (zh) 2021-07-23

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