PL3833343T3 - Heterocykliczne pochodne flawonu, kompozycje, i sposoby z nimi związane - Google Patents
Heterocykliczne pochodne flawonu, kompozycje, i sposoby z nimi związaneInfo
- Publication number
- PL3833343T3 PL3833343T3 PL19847006.4T PL19847006T PL3833343T3 PL 3833343 T3 PL3833343 T3 PL 3833343T3 PL 19847006 T PL19847006 T PL 19847006T PL 3833343 T3 PL3833343 T3 PL 3833343T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- methods related
- flavone derivatives
- heterocyclic
- heterocyclic flavone
- Prior art date
Links
- -1 Heterocyclic flavone derivatives Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862715764P | 2018-08-07 | 2018-08-07 | |
| PCT/US2019/045585 WO2020033604A1 (en) | 2018-08-07 | 2019-08-07 | Heterocyclic flavone derivatives, compositions, and methods related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3833343T3 true PL3833343T3 (pl) | 2024-06-24 |
Family
ID=69415601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19847006.4T PL3833343T3 (pl) | 2018-08-07 | 2019-08-07 | Heterocykliczne pochodne flawonu, kompozycje, i sposoby z nimi związane |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11987589B2 (pl) |
| EP (2) | EP4344743A3 (pl) |
| ES (1) | ES2974972T3 (pl) |
| HU (1) | HUE066348T2 (pl) |
| PL (1) | PL3833343T3 (pl) |
| WO (1) | WO2020033604A1 (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3833343T3 (pl) * | 2018-08-07 | 2024-06-24 | Emory University | Heterocykliczne pochodne flawonu, kompozycje, i sposoby z nimi związane |
| EP4531850A1 (en) | 2022-05-24 | 2025-04-09 | Ontrack Therapeutics Limited | Compounds for use in the treatment of diseases and conditions associated with neurodegenerative dysfunction |
| WO2023227882A1 (en) | 2022-05-24 | 2023-11-30 | Ontrack Therapeutics Limited | 4-(6-oxo-2-(trifluoromethyl)-3,6-dihydrochromeno[7,8-d]imidazol-8-yl)benzonitril e for the treatment of diseases and conditions associated with movement disorders |
| GB202207556D0 (en) * | 2022-05-24 | 2022-07-06 | Ontrack Therapeutics Ltd | Flavonoid compound for use in the treatment of diseases and conditions associated with neurodegenerative dysfunction |
| GB202207557D0 (en) * | 2022-05-24 | 2022-07-06 | Ontrack Therapeutics Ltd | Flavonoid compound for use in the treatment of diseases and conditions associated with movement disorders |
| GB2624633A (en) * | 2022-11-22 | 2024-05-29 | Ontrack Therapeutics Ltd | Compounds for use in the treatment of diseases and conditions associated with inflammation or autoimmunity |
| GB202302121D0 (en) * | 2023-02-14 | 2023-03-29 | Ontrack Therapeutics Ltd | Compounds for use in the treatment of schizophrenia |
| EP4665335A1 (en) * | 2023-02-14 | 2025-12-24 | Ontrack Therapeutics Limited | Compounds for use in the treatment of schizophrenia |
| GB2628348A (en) * | 2023-03-20 | 2024-09-25 | Ontrack Therapeutics Ltd | Amelioration of drug-drug interactions |
| WO2025043434A1 (zh) * | 2023-08-28 | 2025-03-06 | 深圳理工大学 | 阿尔茨海默病的预防和/或治疗药物 |
| GB202317991D0 (en) * | 2023-11-24 | 2024-01-10 | Ontrack Therapeutics Ltd | Compounds for use in the treatment of positive symptoms in schizophrenia |
| WO2025109339A1 (en) * | 2023-11-24 | 2025-05-30 | Ontrack Therapeutics Limited | 4-(6-oxo-2-(trifluoromethyl)-3,6-dihydrochromeno[7,8-d]imidazol-8-yl)benzonitrile for use in the treatment of positive symptoms in schizophrenia |
| GB2636969A (en) * | 2023-11-24 | 2025-07-09 | Ontrack Therapeutics Ltd | Novel crystalline salt forms |
| WO2025125811A1 (en) * | 2023-12-12 | 2025-06-19 | Ontrack Therapeutics Limited | Heterocyclic compounds and their use for the treatment of neurological disorders |
| GB202318964D0 (en) * | 2023-12-12 | 2024-01-24 | Ontrack Therapeutics Ltd | Novel compounds and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS2334B (is) | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| US6043358A (en) | 1995-11-01 | 2000-03-28 | Merck & Co., Inc. | Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases |
| GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| CA2554696C (en) | 2004-02-13 | 2009-06-30 | Warner-Lambert Company Llc | Androgen receptor modulators |
| NZ572374A (en) * | 2006-03-29 | 2011-12-22 | Univ California | Diarylthiohydantoin compounds |
| ES2491140T3 (es) | 2006-06-21 | 2014-09-05 | Piramal Enterprises Limited | Derivados de flavona enantioméricamente puros para el tratamiento de trastornos proliferativos y procesos para su preparación |
| CZ300589B6 (cs) | 2006-09-04 | 2009-06-24 | Univerzita Palackého | Deriváty 2-fenyl-3-hydroxychinolin-4(1H)-onu a zpusob jejich prípravy a použití |
| US9895344B2 (en) | 2008-07-25 | 2018-02-20 | Emory University | Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof |
| WO2010107866A2 (en) | 2009-03-20 | 2010-09-23 | Emory University | Catecholamine derivatives for obesity and neurological disorders |
| CN105566272A (zh) | 2010-06-09 | 2016-05-11 | 爱默蕾大学 | TrkB激动剂及其用途 |
| EP2877461B1 (en) * | 2012-07-27 | 2018-05-09 | Emory University | Heterocyclic flavone derivatives, compositions, and methods related thereto |
| US20160022642A1 (en) * | 2014-07-25 | 2016-01-28 | Yale University | Compounds Useful for Promoting Protein Degradation and Methods Using Same |
| PL3833343T3 (pl) * | 2018-08-07 | 2024-06-24 | Emory University | Heterocykliczne pochodne flawonu, kompozycje, i sposoby z nimi związane |
-
2019
- 2019-08-07 PL PL19847006.4T patent/PL3833343T3/pl unknown
- 2019-08-07 HU HUE19847006A patent/HUE066348T2/hu unknown
- 2019-08-07 EP EP24158115.6A patent/EP4344743A3/en active Pending
- 2019-08-07 ES ES19847006T patent/ES2974972T3/es active Active
- 2019-08-07 US US17/266,863 patent/US11987589B2/en active Active
- 2019-08-07 WO PCT/US2019/045585 patent/WO2020033604A1/en not_active Ceased
- 2019-08-07 EP EP19847006.4A patent/EP3833343B1/en active Active
-
2024
- 2024-04-08 US US18/629,562 patent/US20240262840A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11987589B2 (en) | 2024-05-21 |
| EP3833343C0 (en) | 2024-02-21 |
| ES2974972T3 (es) | 2024-07-02 |
| EP3833343B1 (en) | 2024-02-21 |
| US20210292335A1 (en) | 2021-09-23 |
| WO2020033604A1 (en) | 2020-02-13 |
| EP3833343A1 (en) | 2021-06-16 |
| US20240262840A1 (en) | 2024-08-08 |
| EP3833343A4 (en) | 2022-04-13 |
| EP4344743A3 (en) | 2024-06-19 |
| EP4344743A2 (en) | 2024-04-03 |
| HUE066348T2 (hu) | 2024-07-28 |
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