PL378135A1 - 2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach - Google Patents

2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach

Info

Publication number
PL378135A1
PL378135A1 PL378135A PL37813504A PL378135A1 PL 378135 A1 PL378135 A1 PL 378135A1 PL 378135 A PL378135 A PL 378135A PL 37813504 A PL37813504 A PL 37813504A PL 378135 A1 PL378135 A1 PL 378135A1
Authority
PL
Poland
Prior art keywords
cyanopyrrolopyrimidines
pharmaceutical uses
pharmaceutical
Prior art date
Application number
PL378135A
Other languages
English (en)
Inventor
Francis Paul Buxton
Takeru Ehara
Pamposh Ganju
Allan Hallett
Ozamu Irie
Atsuko Iwasaki
Takanori Kanazawa
Keiichi Masuya
Kazuhiko Nonomura
Junichi Sakaki
Christopher Robert Snell
Chuanheng Song
Keiko Tanabe
Naoki Teno
Ichiro Umemura
Fumiaki Yokokawa
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0302748A external-priority patent/GB0302748D0/en
Priority claimed from GB0304642A external-priority patent/GB0304642D0/en
Priority claimed from GB0304641A external-priority patent/GB0304641D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL378135A1 publication Critical patent/PL378135A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
PL378135A 2003-02-06 2004-02-05 2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach PL378135A1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0302748A GB0302748D0 (en) 2003-02-06 2003-02-06 Organic compounds
GB0304642A GB0304642D0 (en) 2003-02-28 2003-02-28 Organic compounds
GB0304641A GB0304641D0 (en) 2003-02-28 2003-02-28 Organic compounds

Publications (1)

Publication Number Publication Date
PL378135A1 true PL378135A1 (pl) 2006-03-06

Family

ID=32854008

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378135A PL378135A1 (pl) 2003-02-06 2004-02-05 2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach

Country Status (17)

Country Link
US (1) US20060247251A1 (pl)
EP (1) EP1592426B1 (pl)
JP (1) JP4499667B2 (pl)
AR (1) AR043692A1 (pl)
AT (1) ATE381335T1 (pl)
AU (1) AU2004210422B2 (pl)
BR (1) BRPI0407327A (pl)
CA (1) CA2514287A1 (pl)
DE (1) DE602004010785T2 (pl)
ES (1) ES2297378T3 (pl)
HK (1) HK1084883A1 (pl)
MX (1) MXPA05008348A (pl)
PE (1) PE20050068A1 (pl)
PL (1) PL378135A1 (pl)
PT (1) PT1592426E (pl)
TW (1) TW200420566A (pl)
WO (1) WO2004069256A1 (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0201980D0 (sv) 2002-06-24 2002-06-24 Astrazeneca Ab Novel compounds
GB0304640D0 (en) * 2003-02-28 2003-04-02 Novartis Ag Organic compounds
EP1797883A3 (en) * 2003-04-28 2007-08-01 Novartis AG Pharmaceutical composition comprising a cathepsin S inhibitor and an opioid
US7427682B2 (en) * 2004-05-03 2008-09-23 Janssen Pharmaceutica N.V. Indole derivatives as selective androgen receptor modulators (SARMS)
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US8501198B2 (en) 2004-06-07 2013-08-06 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
AR077280A1 (es) 2009-06-29 2011-08-17 Incyte Corp Pirimidinonas como inhibidores de pi3k, y composiciones farmaceuticas que los comprenden
WO2011075643A1 (en) 2009-12-18 2011-06-23 Incyte Corporation Substituted heteroaryl fused derivatives as pi3k inhibitors
UY33304A (es) * 2010-04-02 2011-10-31 Amgen Inc Compuestos heterocíclicos y sus usos
EP2558463A1 (en) 2010-04-14 2013-02-20 Incyte Corporation Fused derivatives as i3 inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
NZ606490A (en) 2010-07-26 2015-04-24 Qu Biolog Inc Immunogenic anti-inflammatory compositions
TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI501967B (zh) * 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TW201249844A (en) 2010-12-20 2012-12-16 Incyte Corp N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines as PI3K inhibitors
WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
SI2751109T1 (sl) 2011-09-02 2017-03-31 Incyte Holdings Corporation Heterociklilamini kot inhibitorji pi3k
CN103304525B (zh) * 2012-03-08 2015-08-05 深圳海王药业有限公司 一种制备达非那新中间体5-(卤代乙基)-2,3-二氢苯并呋喃的方法
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
EA026088B1 (ru) * 2012-04-17 2017-02-28 Астеллас Фарма Инк. Азотсодержащее бициклическое ароматическое гетероциклическое соединение
PT2864323T (pt) * 2012-06-15 2017-07-14 Janssen Sciences Ireland Uc Derivados de 1,3-di-hidro-2h-benzimidazol-2-ona substituídos com heterociclos como agentes antivirais do vírus sincicial respiratório
PL2909195T3 (pl) 2012-10-16 2017-12-29 Janssen Sciences Ireland Uc Związki przeciwwirusowe RSV
JP6387391B2 (ja) * 2013-03-14 2018-09-05 ノバルティス アーゲー 眼科疾患の処置に有用な補体因子Ｂ阻害剤としての２−（１Ｈ−インドール−４−イルメチル）−３Ｈ−イミダゾ［４，５−ｂ］ピリジン−６−カルボニトリル誘導体
JP2016535042A (ja) 2013-10-30 2016-11-10 ノバルティス アーゲー ２−ベンジル−ベンゾイミダゾール補体因子ｂ阻害剤およびその使用
TWI671299B (zh) 2014-04-14 2019-09-11 愛爾蘭商健生科學愛爾蘭無限公司 作為ｒｓｖ抗病毒化合物之螺脲化合物
RU2724895C2 (ru) 2014-05-02 2020-06-26 Кью Байолоджикс Инк. Противомикробная иммуномодуляция
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
CN117800973A (zh) 2015-02-27 2024-04-02 因赛特控股公司 Pi3k抑制剂的盐及其制备方法
US10537552B2 (en) 2015-05-05 2020-01-21 Carafe Drug Innovation, Llc Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
WO2016183060A1 (en) 2015-05-11 2016-11-17 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
BR112020008371A2 (pt) * 2017-10-27 2020-11-03 Esteve Pharmaceuticals, S.A. novos derivados de alcoxiamino para tratamento de dor e condições relacionadas à dor
AR116020A1 (es) 2018-09-03 2021-03-25 Bayer Ag COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT888353E (pt) * 1996-03-15 2003-11-28 Novartis Ag Novas n-7-heterociclil-pirrolo¬2,3-d|pirimidinas e sua aplicacao
AU4710699A (en) * 1998-06-30 2000-01-17 Eli Lilly And Company Bicyclic sPLA2 inhibitors
GB0100622D0 (en) * 2001-01-10 2001-02-21 Vernalis Res Ltd Chemical compounds V111
GB0121033D0 (en) * 2001-08-30 2001-10-24 Novartis Ag Organic compounds
US20030144234A1 (en) * 2001-08-30 2003-07-31 Buxton Francis Paul Methods for the treatment of chronic pain and compositions therefor

Also Published As

Publication number Publication date
ES2297378T3 (es) 2008-05-01
WO2004069256A1 (en) 2004-08-19
HK1084883A1 (en) 2006-08-11
TW200420566A (en) 2004-10-16
EP1592426B1 (en) 2007-12-19
AR043692A1 (es) 2005-08-10
WO2004069256A8 (en) 2004-10-14
DE602004010785T2 (de) 2008-12-04
PE20050068A1 (es) 2005-03-11
AU2004210422A1 (en) 2004-08-19
JP4499667B2 (ja) 2010-07-07
EP1592426A1 (en) 2005-11-09
MXPA05008348A (es) 2005-11-04
US20060247251A1 (en) 2006-11-02
PT1592426E (pt) 2008-03-13
JP2006516554A (ja) 2006-07-06
BRPI0407327A (pt) 2006-01-10
AU2004210422B2 (en) 2008-01-17
ATE381335T1 (de) 2008-01-15
CA2514287A1 (en) 2004-08-19
DE602004010785D1 (de) 2008-01-31

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)