PL374038A1 - Nienukleozydowe inhibitory odwrotnej transkryptazy jako związki antagonistyczne rozrostu komórek i induktory różnicowania komórek - Google Patents

Nienukleozydowe inhibitory odwrotnej transkryptazy jako związki antagonistyczne rozrostu komórek i induktory różnicowania komórek

Info

Publication number
PL374038A1
PL374038A1 PL02374038A PL37403802A PL374038A1 PL 374038 A1 PL374038 A1 PL 374038A1 PL 02374038 A PL02374038 A PL 02374038A PL 37403802 A PL37403802 A PL 37403802A PL 374038 A1 PL374038 A1 PL 374038A1
Authority
PL
Poland
Prior art keywords
inducers
antagonists
reverse transcriptase
cell
cell proliferation
Prior art date
Application number
PL02374038A
Other languages
English (en)
Other versions
PL211565B1 (pl
Inventor
Corrado Spadafora
Patrizia Lavia
Elisabetta Mattei
Guglielmo Palombini
Rodolfo Nello Lorenzini
Clara Nervi
Original Assignee
Istituto Superiore Di Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITRM20010767 external-priority patent/ITRM20010767A1/it
Priority claimed from ITMI20021833 external-priority patent/ITMI20021833A1/it
Application filed by Istituto Superiore Di Sanita filed Critical Istituto Superiore Di Sanita
Publication of PL374038A1 publication Critical patent/PL374038A1/pl
Publication of PL211565B1 publication Critical patent/PL211565B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL374038A 2001-12-24 2002-12-23 Zastosowanie nienukleozydowych inhibitorów odwrotnej transkryptazy jako związków antagonistycznych rozrostu komórek i induktorów różnicowania komórek PL211565B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM20010767 ITRM20010767A1 (it) 2001-12-24 2001-12-24 Uso di 5.11-diidro-6h-dipirido1/4 3,2-b:2',3'-e|1/4 1.4|diazepine per la preparazione di composizioni farmaceutiche antitumorali.
ITMI20021833 ITMI20021833A1 (it) 2002-08-19 2002-08-19 Inibitori non nucleosidici della trascrittasi inversa come induttori del differenziamento cellulare.

Publications (2)

Publication Number Publication Date
PL374038A1 true PL374038A1 (pl) 2005-09-19
PL211565B1 PL211565B1 (pl) 2012-05-31

Family

ID=26332794

Family Applications (1)

Application Number Title Priority Date Filing Date
PL374038A PL211565B1 (pl) 2001-12-24 2002-12-23 Zastosowanie nienukleozydowych inhibitorów odwrotnej transkryptazy jako związków antagonistycznych rozrostu komórek i induktorów różnicowania komórek

Country Status (22)

Country Link
US (1) US10507207B2 (pl)
EP (1) EP1469858B1 (pl)
JP (1) JP4336584B2 (pl)
CN (1) CN100450487C (pl)
AP (1) AP1958A (pl)
AT (1) ATE400276T1 (pl)
AU (1) AU2002358793B2 (pl)
CA (1) CA2471543C (pl)
CY (1) CY1108396T1 (pl)
DE (1) DE60227563D1 (pl)
DK (1) DK1469858T3 (pl)
EA (1) EA007004B1 (pl)
ES (1) ES2309222T3 (pl)
HU (1) HU229522B1 (pl)
IL (2) IL162680A0 (pl)
MX (1) MXPA04006205A (pl)
NZ (1) NZ534257A (pl)
OA (1) OA13140A (pl)
PL (1) PL211565B1 (pl)
PT (1) PT1469858E (pl)
SI (1) SI1469858T1 (pl)
WO (1) WO2003055493A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
CA2796620A1 (en) * 2010-06-04 2011-12-08 North-West University Injectable formulation
MX2015009546A (es) * 2013-01-23 2015-11-25 Alienor Farma Dosificacion aumentada de efavirenz para el tratamiento de cancer.
WO2016156557A1 (en) 2015-04-03 2016-10-06 Alienor Farma Monoclonal antibody to human line-1 orf2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject
CN113384585A (zh) * 2021-04-16 2021-09-14 蓝龙药业(北京)有限公司 依法韦仑在制备治疗小细胞肺癌的药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258839B1 (en) * 1997-12-24 2001-07-10 Peter Mashava Isolation of naturally occuring isoflavanone and some clinical uses thereof

Also Published As

Publication number Publication date
JP2005513147A (ja) 2005-05-12
PL211565B1 (pl) 2012-05-31
US20060166970A1 (en) 2006-07-27
AP1958A (en) 2009-02-20
IL162680A (en) 2010-11-30
CN1607953A (zh) 2005-04-20
US10507207B2 (en) 2019-12-17
EP1469858B1 (en) 2008-07-09
WO2003055493A1 (en) 2003-07-10
DK1469858T3 (da) 2008-09-29
ES2309222T3 (es) 2008-12-16
AP2004003088A0 (en) 2004-09-30
MXPA04006205A (es) 2005-07-25
CN100450487C (zh) 2009-01-14
AU2002358793A1 (en) 2003-07-15
EP1469858A1 (en) 2004-10-27
DE60227563D1 (de) 2008-08-21
EA007004B1 (ru) 2006-06-30
CA2471543A1 (en) 2003-07-10
IL162680A0 (en) 2005-11-20
HUP0600841A3 (en) 2012-09-28
AU2002358793B2 (en) 2008-04-24
NZ534257A (en) 2008-03-28
HUP0600841A2 (en) 2007-05-02
CY1108396T1 (el) 2014-02-12
HU229522B1 (en) 2014-01-28
ATE400276T1 (de) 2008-07-15
SI1469858T1 (sl) 2008-10-31
EA200400861A1 (ru) 2004-12-30
CA2471543C (en) 2011-03-22
OA13140A (en) 2006-12-13
PT1469858E (pt) 2008-10-01
JP4336584B2 (ja) 2009-09-30
HK1074998A1 (zh) 2005-12-02

Similar Documents

Publication Publication Date Title
PL344248A1 (en) Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation
IL149100A0 (en) Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase
HU0304052D0 (en) Heterocyclic inhibitors of erk2 and uses thereof
IL149230A0 (en) Alkylamino substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase
EP1085871A4 (en) QUINAZOLINONE INHIBITORS FROM CGMP PHOSPHODIESTERASE
EP1383743A4 (en) DOUBLE INHIBITORS OF PDE 7 AND PDE 4
PL369855A1 (pl) 4-arylochinazoliny i ich zastosowanie jako inhibitorów NHE-3
HUP0401729A3 (en) Alkyne-aryl-naphthyridin-4(1h)-one derivaties as phosphodiesterase-4 inhibitors and pharmaceutical compositions containing them
PL367058A1 (pl) Nowe spirotricykliczne pochodne i ich zastosowanie jako inhibitorów fosfodiesterazy-7
IL153246A0 (en) Substituted quinazoline derivatives and their use as inhibitors
IL157109A0 (en) Quinazolines as mmp-13 inhibitors
AU2002323337A1 (en) Use of dppiv inhibitors as diuretic and anti-hypertensive agents
PL374221A1 (pl) Inhibitory przeciwciałowe GDF-8 i ich zastosowania
PL344046A1 (en) Heterocyclic inhibitors of p38
IL134013A (en) Substituted quinazoline derivatives and their use as tyrosine kinase inhibitors
PL364230A1 (pl) Pochodne benzimidazolowe stosowane do modulowaniaIgE oraz hamowania proliferacji komórkowej
IL159538A0 (en) 8/17 heterocyclic compounds and uses thereof as d-alanyl-d-alanine ligase inhibitors
EP1372654A4 (en) QUINOLINE INHIBITORS OF HYAK1 AND HYAK3 KINASES
GB0322131D0 (en) Absorbent garment and method of providing the same
PL370657A1 (pl) Pochodne chinazolinonowe i ich zastosowanie jako agonistów CB
GB2355260B (en) Low-temperature sinterable ceramic composition and multilayer ceramic substrate
HUP0600841A3 (en) Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation
PL361733A1 (pl) Sulfamidotienopirymidyny
HUP0204376A3 (en) Novel invertase inhibitors and methods of use
AU2002352696A8 (en) Cell substrates and methods of use thereof