PL372882A1 - 1,2-Dihydropirazol-3-ony jako mediatory cytokin - Google Patents
1,2-Dihydropirazol-3-ony jako mediatory cytokinInfo
- Publication number
- PL372882A1 PL372882A1 PL03372882A PL37288203A PL372882A1 PL 372882 A1 PL372882 A1 PL 372882A1 PL 03372882 A PL03372882 A PL 03372882A PL 37288203 A PL37288203 A PL 37288203A PL 372882 A1 PL372882 A1 PL 372882A1
- Authority
- PL
- Poland
- Prior art keywords
- dihydropyrazol
- ones
- cytokine mediators
- mediators
- cytokine
- Prior art date
Links
- XBYRMPXUBGMOJC-UHFFFAOYSA-N 1,2-dihydropyrazol-3-one Chemical class OC=1C=CNN=1 XBYRMPXUBGMOJC-UHFFFAOYSA-N 0.000 title 1
- 102000004127 Cytokines Human genes 0.000 title 1
- 108090000695 Cytokines Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36570102P | 2002-03-19 | 2002-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL372882A1 true PL372882A1 (pl) | 2005-08-08 |
Family
ID=28454704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL03372882A PL372882A1 (pl) | 2002-03-19 | 2003-03-12 | 1,2-Dihydropirazol-3-ony jako mediatory cytokin |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6677337B2 (pl) |
| EP (1) | EP1485167A1 (pl) |
| JP (1) | JP2006502093A (pl) |
| KR (1) | KR20040093158A (pl) |
| CN (1) | CN1642600A (pl) |
| AR (1) | AR039001A1 (pl) |
| AU (1) | AU2003220216A1 (pl) |
| BR (1) | BR0308579A (pl) |
| CA (1) | CA2477091A1 (pl) |
| CO (1) | CO5611175A2 (pl) |
| IL (1) | IL163712A0 (pl) |
| MA (1) | MA27784A1 (pl) |
| MX (1) | MXPA04009088A (pl) |
| MY (1) | MY134226A (pl) |
| NO (1) | NO20044413L (pl) |
| NZ (1) | NZ534869A (pl) |
| PE (1) | PE20040160A1 (pl) |
| PL (1) | PL372882A1 (pl) |
| RU (1) | RU2004130843A (pl) |
| TW (1) | TW200306182A (pl) |
| WO (1) | WO2003080184A1 (pl) |
| ZA (1) | ZA200407135B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7473695B2 (en) * | 2001-10-22 | 2009-01-06 | Mitsubishi Tanabe Pharma Corporation | 4-imidazolin-2-one compounds |
| EP1542680B1 (en) * | 2002-09-09 | 2007-03-07 | Amgen Inc. | 1, 4, 5-substituted 1, 2-dihydro-pyrazol-3-one and 3-alkoxy-1h-pyrazole derivatives as tnf-alpha and interleukin lowering agents for the treatment of inflammations |
| US7482356B2 (en) * | 2003-11-10 | 2009-01-27 | The Procter & Gamble Company | Bicyclic pyrazolone cytokine inhibitors |
| US8153630B2 (en) * | 2004-11-17 | 2012-04-10 | Miikana Therapeutics, Inc. | Kinase inhibitors |
| CA2618377A1 (en) | 2005-08-12 | 2007-02-22 | Synta Pharmaceuticals Corp. | Pyrazole compounds that modulate hsp90 activity |
| ES2535854T3 (es) * | 2005-09-30 | 2015-05-18 | Miikana Therapeutics, Inc. | Compuestos de pirazol sustituidos |
| AU2008262291A1 (en) * | 2007-06-11 | 2008-12-18 | Miikana Therapeutics, Inc. | Substituted pyrazole compounds |
| WO2018192793A1 (en) | 2017-04-20 | 2018-10-25 | Basf Se | Substituted rhodanine derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663327A (en) * | 1984-05-23 | 1987-05-05 | Bayer Aktiengesellschaft | 1-heteroaryl-4-aryl-pyrazolin-5-ones |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| EP1343781B1 (en) * | 2000-12-05 | 2008-09-03 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| US6884804B2 (en) * | 2001-05-16 | 2005-04-26 | Vertex Pharmaceuticals Incorporated | Inhibitors of Src and other protein kinases |
| US6821971B2 (en) * | 2001-09-20 | 2004-11-23 | The Procter & Gamble Company | Fused pyrazolone compounds which inhibit the release of inflammatory cytokines |
-
2003
- 2003-03-05 US US10/382,060 patent/US6677337B2/en not_active Expired - Fee Related
- 2003-03-12 MX MXPA04009088A patent/MXPA04009088A/es unknown
- 2003-03-12 IL IL16371203A patent/IL163712A0/xx unknown
- 2003-03-12 CA CA002477091A patent/CA2477091A1/en not_active Abandoned
- 2003-03-12 EP EP03716512A patent/EP1485167A1/en not_active Withdrawn
- 2003-03-12 CN CNA038062003A patent/CN1642600A/zh active Pending
- 2003-03-12 AU AU2003220216A patent/AU2003220216A1/en not_active Abandoned
- 2003-03-12 NZ NZ534869A patent/NZ534869A/en unknown
- 2003-03-12 PL PL03372882A patent/PL372882A1/pl not_active Application Discontinuation
- 2003-03-12 BR BR0308579-1A patent/BR0308579A/pt not_active IP Right Cessation
- 2003-03-12 RU RU2004130843/04A patent/RU2004130843A/ru not_active Application Discontinuation
- 2003-03-12 JP JP2003578007A patent/JP2006502093A/ja active Pending
- 2003-03-12 KR KR10-2004-7014642A patent/KR20040093158A/ko active IP Right Grant
- 2003-03-12 WO PCT/US2003/007635 patent/WO2003080184A1/en active Application Filing
- 2003-03-14 PE PE2003000262A patent/PE20040160A1/es not_active Application Discontinuation
- 2003-03-14 TW TW092105683A patent/TW200306182A/zh unknown
- 2003-03-18 MY MYPI20030939A patent/MY134226A/en unknown
- 2003-03-18 AR ARP030100936A patent/AR039001A1/es not_active Application Discontinuation
-
2004
- 2004-09-07 ZA ZA200407135A patent/ZA200407135B/en unknown
- 2004-09-09 MA MA27850A patent/MA27784A1/fr unknown
- 2004-09-23 CO CO04094890A patent/CO5611175A2/es not_active Application Discontinuation
- 2004-10-18 NO NO20044413A patent/NO20044413L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20030225082A1 (en) | 2003-12-04 |
| PE20040160A1 (es) | 2004-04-30 |
| US6677337B2 (en) | 2004-01-13 |
| MXPA04009088A (es) | 2004-12-06 |
| WO2003080184A1 (en) | 2003-10-02 |
| BR0308579A (pt) | 2005-01-25 |
| IL163712A0 (en) | 2005-12-18 |
| MY134226A (en) | 2007-11-30 |
| RU2004130843A (ru) | 2005-08-27 |
| AR039001A1 (es) | 2005-02-02 |
| CO5611175A2 (es) | 2006-02-28 |
| JP2006502093A (ja) | 2006-01-19 |
| ZA200407135B (en) | 2005-09-21 |
| CN1642600A (zh) | 2005-07-20 |
| CA2477091A1 (en) | 2003-10-02 |
| NZ534869A (en) | 2006-09-29 |
| TW200306182A (en) | 2003-11-16 |
| EP1485167A1 (en) | 2004-12-15 |
| MA27784A1 (fr) | 2006-03-01 |
| NO20044413L (no) | 2004-10-18 |
| KR20040093158A (ko) | 2004-11-04 |
| AU2003220216A1 (en) | 2003-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |