PL372418A1 - 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors - Google Patents

1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors

Info

Publication number
PL372418A1
PL372418A1 PL03372418A PL37241803A PL372418A1 PL 372418 A1 PL372418 A1 PL 372418A1 PL 03372418 A PL03372418 A PL 03372418A PL 37241803 A PL37241803 A PL 37241803A PL 372418 A1 PL372418 A1 PL 372418A1
Authority
PL
Poland
Prior art keywords
ligands
receptors
triazine derivatives
human adenosine
adenosine
Prior art date
Application number
PL03372418A
Other languages
English (en)
Polish (pl)
Inventor
Hartog Jacobus A.J. Den
Jan H. Reinders
Scharrenburg Guustaaf J.M. Van
Maria L. Pras-Raves
Gary R. Gustafson
Original Assignee
Solvay Pharmaceuticals B.V.
Arqule Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals B.V., Arqule Inc. filed Critical Solvay Pharmaceuticals B.V.
Publication of PL372418A1 publication Critical patent/PL372418A1/xx

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/48Two nitrogen atoms
    • C07D251/50Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
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  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
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  • Urology & Nephrology (AREA)
  • Obesity (AREA)
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PL03372418A 2002-05-30 2003-05-28 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors PL372418A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02077310 2002-05-30

Publications (1)

Publication Number Publication Date
PL372418A1 true PL372418A1 (en) 2005-07-25

Family

ID=29595045

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03372418A PL372418A1 (en) 2002-05-30 2003-05-28 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors

Country Status (16)

Country Link
EP (1) EP1513827A1 (de)
JP (1) JP4590260B2 (de)
CN (1) CN1329388C (de)
AR (1) AR040231A1 (de)
AU (1) AU2003250232B2 (de)
BR (1) BR0304925A (de)
CA (1) CA2484981C (de)
HK (1) HK1075045A1 (de)
HR (1) HRP20040970A2 (de)
IL (1) IL164240A (de)
MX (1) MXPA04011948A (de)
PL (1) PL372418A1 (de)
RU (1) RU2312859C2 (de)
UA (1) UA77816C2 (de)
WO (1) WO2003101980A1 (de)
ZA (1) ZA200408029B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005009980A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
WO2005028467A1 (en) 2003-09-15 2005-03-31 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substitute aromatic and heteroaromatic compounds
GB2465405A (en) * 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy
BR112014032873B1 (pt) 2012-07-04 2019-02-12 Agro-Kanesho Co., Ltd. Derivado de éster de ácido 2-aminonicotínico, e, bactericida
GB201810668D0 (en) 2018-06-28 2018-08-15 Stiftelsen Alzecure New compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226735D0 (en) * 1992-12-22 1993-02-17 Ici Plc Azole derivatives
DE19735800A1 (de) * 1997-08-18 1999-02-25 Boehringer Ingelheim Pharma Triazine mit adenosinantagonistischer Wirkung
JPH11158073A (ja) * 1997-09-26 1999-06-15 Takeda Chem Ind Ltd アデノシンa3拮抗剤

Also Published As

Publication number Publication date
JP4590260B2 (ja) 2010-12-01
CN1329388C (zh) 2007-08-01
AU2003250232B2 (en) 2008-09-11
IL164240A0 (en) 2005-12-18
RU2004138803A (ru) 2005-06-10
IL164240A (en) 2010-12-30
JP2005531600A (ja) 2005-10-20
RU2312859C2 (ru) 2007-12-20
HRP20040970A2 (en) 2005-06-30
AR040231A1 (es) 2005-03-23
AU2003250232A1 (en) 2003-12-19
UA77816C2 (en) 2007-01-15
WO2003101980A1 (en) 2003-12-11
CN1646520A (zh) 2005-07-27
EP1513827A1 (de) 2005-03-16
ZA200408029B (en) 2005-10-06
CA2484981C (en) 2011-07-26
CA2484981A1 (en) 2003-12-11
BR0304925A (pt) 2004-09-28
MXPA04011948A (es) 2005-03-31
HK1075045A1 (en) 2005-12-02

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