PL360991A1 - Związki laktamowe - Google Patents

Związki laktamowe

Info

Publication number
PL360991A1
PL360991A1 PL36099101A PL36099101A PL360991A1 PL 360991 A1 PL360991 A1 PL 360991A1 PL 36099101 A PL36099101 A PL 36099101A PL 36099101 A PL36099101 A PL 36099101A PL 360991 A1 PL360991 A1 PL 360991A1
Authority
PL
Poland
Prior art keywords
lactam compound
lactam
compound
Prior art date
Application number
PL36099101A
Other languages
English (en)
Other versions
PL211018B1 (pl
Inventor
Thomas Mitchell Koenig
James Edmund Audia
David Mitchell
Stacey Leigh Mcdaniel
Lynne Ann Buccilli
Gary Lowell Engel
James Abraham Aikins
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of PL360991A1 publication Critical patent/PL360991A1/pl
Publication of PL211018B1 publication Critical patent/PL211018B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
PL360991A 2000-11-17 2001-11-02 Krystaliczny związek laktamowy, kompozycja farmaceutyczna i sposób wytwarzania krystalicznego związku laktamowego PL211018B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17
PCT/US2001/027795 WO2002040451A2 (en) 2000-11-17 2001-11-02 Lactam compound

Publications (2)

Publication Number Publication Date
PL360991A1 true PL360991A1 (pl) 2004-09-20
PL211018B1 PL211018B1 (pl) 2012-03-30

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
PL360991A PL211018B1 (pl) 2000-11-17 2001-11-02 Krystaliczny związek laktamowy, kompozycja farmaceutyczna i sposób wytwarzania krystalicznego związku laktamowego

Country Status (33)

Country Link
US (1) US20040248878A1 (pl)
EP (1) EP1353910B1 (pl)
JP (1) JP4116431B2 (pl)
KR (1) KR20030045194A (pl)
CN (2) CN100516047C (pl)
AR (1) AR031356A1 (pl)
AT (1) ATE362919T1 (pl)
AU (2) AU2432102A (pl)
BR (1) BR0115424A (pl)
CA (1) CA2425497C (pl)
CY (1) CY1106682T1 (pl)
CZ (1) CZ20031340A3 (pl)
DE (1) DE60128587T2 (pl)
DK (1) DK1353910T3 (pl)
DZ (1) DZ3454A1 (pl)
EA (1) EA006919B1 (pl)
EC (1) ECSP034598A (pl)
ES (1) ES2286162T3 (pl)
HR (1) HRP20030385A2 (pl)
HU (1) HUP0301862A3 (pl)
IL (1) IL155275A0 (pl)
MX (1) MXPA03004250A (pl)
MY (1) MY141607A (pl)
NO (1) NO325217B1 (pl)
PE (1) PE20020798A1 (pl)
PL (1) PL211018B1 (pl)
PT (1) PT1353910E (pl)
SK (1) SK287794B6 (pl)
SV (1) SV2003000741A (pl)
TW (1) TWI235151B (pl)
UA (1) UA77165C2 (pl)
WO (1) WO2002040451A2 (pl)
ZA (1) ZA200303411B (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
NZ540148A (en) 2002-12-20 2007-11-30 Glaxo Group Ltd Benzazepine derivatives for the treatment of neurological disorders
PT1599468E (pt) 2003-01-14 2008-01-14 Arena Pharm Inc Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
US8114886B2 (en) 2005-04-08 2012-02-14 Daiichi Sankyo Company, Limited Pyridylmethylsulfone derivative
EP1985615A4 (en) * 2006-01-31 2011-12-14 Api Corp PROCESS FOR THE PREPARATION OF BENZAZEPINONE
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
JP5941916B2 (ja) 2010-09-22 2016-06-29 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
WO2014171434A1 (ja) 2013-04-19 2014-10-23 国立大学法人岡山大学 アミロイドβ蛋白質により誘発される認知障害の治療剤およびアルツハイマー病治療薬、ならびにこれらに関連する治療方法および病態解析方法
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
DK3310760T3 (da) 2015-06-22 2022-10-24 Arena Pharm Inc Krystallinsk L-argininsalt af (R)-2-(7-(4-cyclopentyl-3-(trifluormethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3- yl)eddikesyre til anvendelse ved S1P1-receptor-associerede lidelser
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
BR112020024762A2 (pt) 2018-06-06 2021-03-23 Arena Pharmaceuticals, Inc. métodos de tratamento de condições relacionadas ao receptor s1p1
JP2023520771A (ja) 2020-03-26 2023-05-19 シージェン インコーポレイテッド 多発性骨髄腫を処置する方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0951466T3 (da) * 1996-12-23 2009-03-16 Elan Pharm Inc Cycloalkyl-, lactam, lacton- og beslægtede forbindelser, farmaceutiske sammensætninger, der omfatter samme, og fremgangsmåder til inhibering af beta-amyloidpeptidfrigivelse og/eller dets syntese ved anvendelse af sådanne forbindelser
JP2002518481A (ja) * 1998-06-22 2002-06-25 エラン ファーマシューティカルズ，インコーポレイテッド β−アミロイドペプチドの放出および／またはその合成を阻害するための化合物
EP1230220A1 (en) * 1999-11-09 2002-08-14 Eli Lilly And Company Beta-aminoacid compounds useful for inhibiting beta-amyloid peptide release and/or its synthesis

Also Published As

Publication number Publication date
PT1353910E (pt) 2007-08-20
DK1353910T3 (da) 2007-09-10
MXPA03004250A (es) 2003-09-22
AU2002224321B2 (en) 2006-10-19
NO325217B1 (no) 2008-02-25
CN101624372A (zh) 2010-01-13
JP2004521084A (ja) 2004-07-15
SK5432003A3 (en) 2004-09-08
PE20020798A1 (es) 2002-09-06
ZA200303411B (en) 2004-08-02
EA006919B1 (ru) 2006-04-28
TWI235151B (en) 2005-07-01
EP1353910A2 (en) 2003-10-22
HUP0301862A3 (en) 2007-09-28
WO2002040451A2 (en) 2002-05-23
HRP20030385A2 (en) 2003-08-31
IL155275A0 (en) 2003-11-23
US20040248878A1 (en) 2004-12-09
AU2432102A (en) 2002-05-27
DE60128587T2 (de) 2008-01-31
DZ3454A1 (fr) 2002-05-23
CN100516047C (zh) 2009-07-22
ECSP034598A (es) 2003-06-25
UA77165C2 (en) 2006-11-15
BR0115424A (pt) 2003-10-21
NO20032215D0 (no) 2003-05-15
HUP0301862A2 (hu) 2003-09-29
NO20032215L (no) 2003-07-16
KR20030045194A (ko) 2003-06-09
CY1106682T1 (el) 2012-05-23
ATE362919T1 (de) 2007-06-15
JP4116431B2 (ja) 2008-07-09
AR031356A1 (es) 2003-09-17
ES2286162T3 (es) 2007-12-01
CZ20031340A3 (cs) 2004-06-16
CN1575282A (zh) 2005-02-02
CA2425497A1 (en) 2002-05-23
EP1353910B1 (en) 2007-05-23
WO2002040451A3 (en) 2003-08-28
SK287794B6 (sk) 2011-10-04
SV2003000741A (es) 2003-01-13
MY141607A (en) 2010-05-31
PL211018B1 (pl) 2012-03-30
CA2425497C (en) 2010-08-17
EA200300579A1 (ru) 2003-12-25
DE60128587D1 (de) 2007-07-05

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Legal Events

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RECP Rectifications of patent specification