PL3555107T3 - Sposób wytwarzania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu - Google Patents

Sposób wytwarzania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu

Info

Publication number
PL3555107T3
PL3555107T3 PL17835634T PL17835634T PL3555107T3 PL 3555107 T3 PL3555107 T3 PL 3555107T3 PL 17835634 T PL17835634 T PL 17835634T PL 17835634 T PL17835634 T PL 17835634T PL 3555107 T3 PL3555107 T3 PL 3555107T3
Authority
PL
Poland
Prior art keywords
oxooxazolidin
oxazepin
dihydrobenzo
propanamide
imidazo
Prior art date
Application number
PL17835634T
Other languages
English (en)
Inventor
Francis Gosselin
Chong Han
Theresa CRAVILLION
Sean M. Kelly
Scott Savage
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3555107T3 publication Critical patent/PL3555107T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL17835634T 2016-12-15 2017-12-15 Sposób wytwarzania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu PL3555107T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662434836P 2016-12-15 2016-12-15
EP17835634.1A EP3555107B1 (en) 2016-12-15 2017-12-15 Process for the preparation of (s)-2-((2-((s)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide
PCT/EP2017/083143 WO2018109204A1 (en) 2016-12-15 2017-12-15 Process for the preparation of (s)-2-((2-((s)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino) propanamide

Publications (1)

Publication Number Publication Date
PL3555107T3 true PL3555107T3 (pl) 2021-07-05

Family

ID=61027659

Family Applications (2)

Application Number Title Priority Date Filing Date
PL17835634T PL3555107T3 (pl) 2016-12-15 2017-12-15 Sposób wytwarzania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu
PL20209166.6T PL3851441T3 (pl) 2016-12-15 2017-12-15 Proces otrzymywania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL20209166.6T PL3851441T3 (pl) 2016-12-15 2017-12-15 Proces otrzymywania (S)-2-((2-((S)-4-(difluorometylo)-2-oksooksazolidyn-3-ylo)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oksazepin-9-ylo)amino)propanamidu

Country Status (19)

Country Link
US (1) US10781219B2 (pl)
EP (2) EP3555107B1 (pl)
JP (1) JP7004720B2 (pl)
KR (1) KR102537048B1 (pl)
CN (1) CN110088111B (pl)
AR (1) AR110527A1 (pl)
AU (2) AU2017378188B2 (pl)
BR (1) BR112019010481A2 (pl)
CA (1) CA3044500A1 (pl)
ES (2) ES2953833T3 (pl)
HR (2) HRP20230948T1 (pl)
HU (1) HUE062517T2 (pl)
IL (2) IL267265B (pl)
MX (2) MX2019006958A (pl)
PL (2) PL3555107T3 (pl)
SG (1) SG10201913961PA (pl)
SI (1) SI3555107T1 (pl)
TW (1) TWI770093B (pl)
WO (1) WO2018109204A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9650393B2 (en) 2015-07-02 2017-05-16 Genentech, Inc. Benzoxazepin oxazolidinone compounds and methods of use
WO2018197653A1 (en) * 2017-04-28 2018-11-01 F. Hoffmann-La Roche Ag Polymorphs and solid forms of (s)-2-((2-((s)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide, and methods of production
CA3159094A1 (en) * 2019-11-25 2021-06-03 Shanghai Hansoh Biomedical Co., Ltd. Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof
KR20220143680A (ko) * 2020-03-03 2022-10-25 모멘티브 퍼포먼스 머티리얼즈 인크. 촉매 조성물
WO2022251567A1 (en) 2021-05-28 2022-12-01 Genentech, Inc. Process for the preparation of benzoxazepin oxazolidinone compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2600927C2 (ru) 2009-09-28 2016-10-27 Ф.Хоффманн-Ля Рош Аг Бензоксазепиновые ингибиторы pi3k и способы применения
WO2012126901A1 (en) 2011-03-21 2012-09-27 F. Hoffmann-La Roche Ag Benzoxazepin compounds selective for pi3k p110 delta and methods of use
BR112015020716A2 (pt) 2013-03-13 2017-07-18 Hoffmann La Roche processo para a preparação de (2-(4-(2-(1-isopropil-3-metil-1h-1,2,4-triazol-5-il)-5,6-diidrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-il)-1h-pirazol-1-il)-2-metilpropanamida (i) e composto
US9650393B2 (en) * 2015-07-02 2017-05-16 Genentech, Inc. Benzoxazepin oxazolidinone compounds and methods of use
WO2018197653A1 (en) 2017-04-28 2018-11-01 F. Hoffmann-La Roche Ag Polymorphs and solid forms of (s)-2-((2-((s)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide, and methods of production

Also Published As

Publication number Publication date
MX2020010948A (es) 2021-01-08
PL3851441T3 (pl) 2023-11-06
US20190292201A1 (en) 2019-09-26
CN110088111B (zh) 2021-08-03
JP2020502143A (ja) 2020-01-23
CN110088111A (zh) 2019-08-02
JP7004720B2 (ja) 2022-01-21
EP3555107B1 (en) 2021-02-17
HUE062517T2 (hu) 2023-11-28
IL267265B (en) 2021-03-25
KR102537048B1 (ko) 2023-05-26
IL281087A (en) 2021-04-29
TWI770093B (zh) 2022-07-11
AU2017378188A1 (en) 2019-05-30
ES2867389T3 (es) 2021-10-20
MX2019006958A (es) 2019-08-01
HRP20210592T1 (hr) 2021-05-14
EP3851441A1 (en) 2021-07-21
BR112019010481A2 (pt) 2019-09-10
AU2021201046A1 (en) 2021-03-11
SI3555107T1 (sl) 2021-07-30
EP3555107A1 (en) 2019-10-23
SG10201913961PA (en) 2020-03-30
KR20190093654A (ko) 2019-08-09
EP3851441B1 (en) 2023-06-28
WO2018109204A1 (en) 2018-06-21
ES2953833T3 (es) 2023-11-16
AU2017378188B2 (en) 2020-11-26
US10781219B2 (en) 2020-09-22
HRP20230948T1 (hr) 2023-11-24
EP3851441C0 (en) 2023-06-28
TW201837044A (zh) 2018-10-16
IL267265A (en) 2019-08-29
AR110527A1 (es) 2019-04-10
CA3044500A1 (en) 2018-06-21

Similar Documents

Publication Publication Date Title
IL281087A (en) Process for preparing (S)-2-((2-((S)-4-(difluoromethyl)-2-oxoxazolidine-3-YL)-6,5-dihydrobenzo[F]imidazo[2,1-D][4 , 1]oxazapine-9-YL)amino)propanamide
IL267464A (en) Polymorphs and solid forms of (s)-2-((2-((s-4-(difluoromethyl)-2-oxoxolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][ 1,4]oxazepin-9-yl)amino)propanamide and methods of production
IL266170A (en) A process for the preparation of pyrazolo[1,5-a]pyrimidines and their salts
IL263911B (en) Synthesis of n-(heteroaryl)-pyrrolo[2,3-d]pyrimidine-2-amines
IL286912A (en) Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]-3-oxo-5,6,8,8a-tetrahydro-1h-imidazo[1,5-a]pyrazin-2-yl]-carboxylic acid
SI3097098T1 (sl) Postopek za pripravo N-((3-aminooksetana-3-il)metil)-2-(1,1-diokso- 3,5-dihidro-1,4-benzotiazepin-4-il)-6-metil-kinazolin-4-amina
PT3580219T (pt) Processo para a preparação de remimazolam e formas de estado sólido de sais de remimazolam
HK1259183A1 (zh) 一種吡咯並[3，2-d]嘧啶類化合物的製備方法及其中間體
IL288080A (en) A process for the preparation of h7-pyrrolo[3,2-d]pyrimidine derivatives and their artificial intermediates
EP3405456A4 (en) PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-ACETOXYPICOLINIC ACIDS
HK1223101A1 (zh) -異丙基- -甲基- -三唑- -基 -二氫苯並 咪唑並 氧氮雜䓬- -基 -吡唑- -基 -甲基丙酰胺的多晶型物、其製備方法和藥物用途
EP3422855A4 (en) PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLIC ACIDS
EP3436439A4 (en) METHOD FOR PRODUCING DIPHENYLPYRAZINE DERIVATIVES
EP3405034A4 (en) PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLIC ACIDS
AU2018297073A1 (en) Process for the preparation of morphinane compounds
EP3294703A4 (en) A process for the preparation of verapamil hydrochloride
IL274560A (en) A process for the preparation of raltagravir
HK1257427A1 (zh) 用於製備2-吡唑並[1，5-a]吡嗪-2-基吡啶並[1，2-a]嘧啶-4-酮的方法
HUE058725T2 (hu) Eljárás aminok elõállítására
IL265013B (en) Process for the preparation of 2-(6-nitropyridin-3-yl)-9h-dipyrido[3,2-b;3',4'-d]pyrrole
HUP1800397A2 (en) Process for the preparation of lumateperone and salts thereof
HK1218683A2 (zh) 製備營養製劑的方法