PL3527556T3 - Sposób wytwarzania deuterowanych związków imidazolodiketonowych - Google Patents
Sposób wytwarzania deuterowanych związków imidazolodiketonowychInfo
- Publication number
- PL3527556T3 PL3527556T3 PL16919556.7T PL16919556T PL3527556T3 PL 3527556 T3 PL3527556 T3 PL 3527556T3 PL 16919556 T PL16919556 T PL 16919556T PL 3527556 T3 PL3527556 T3 PL 3527556T3
- Authority
- PL
- Poland
- Prior art keywords
- diketone compound
- imidazole diketone
- preparing deuterated
- deuterated imidazole
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610901502.0A CN107954936B (zh) | 2016-10-17 | 2016-10-17 | 一种制备氘代咪唑二酮类化合物的方法 |
| PCT/CN2016/110978 WO2018072300A1 (zh) | 2016-10-17 | 2016-12-20 | 一种制备氘代咪唑二酮类化合物的方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3527556T3 true PL3527556T3 (pl) | 2023-08-14 |
Family
ID=61954120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16919556.7T PL3527556T3 (pl) | 2016-10-17 | 2016-12-20 | Sposób wytwarzania deuterowanych związków imidazolodiketonowych |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20200087261A1 (pl) |
| EP (1) | EP3527556B1 (pl) |
| JP (1) | JP7241682B2 (pl) |
| CN (1) | CN107954936B (pl) |
| AU (1) | AU2016426847B2 (pl) |
| CA (1) | CA3040785C (pl) |
| DK (1) | DK3527556T3 (pl) |
| ES (1) | ES2943011T3 (pl) |
| FI (1) | FI3527556T3 (pl) |
| HU (1) | HUE061557T2 (pl) |
| PL (1) | PL3527556T3 (pl) |
| PT (1) | PT3527556T (pl) |
| TW (1) | TWI728077B (pl) |
| WO (1) | WO2018072300A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109180511A (zh) * | 2018-08-22 | 2019-01-11 | 辽宁东科药业有限公司 | 一种盐酸丁卡因的制备方法 |
| CN114621109B (zh) * | 2020-12-14 | 2024-04-26 | 成都苑东生物制药股份有限公司 | 一种阿帕他胺的合成方法及其中间体 |
| CN113698310B (zh) * | 2021-08-20 | 2023-03-17 | 江西金丰药业有限公司 | 一种恩杂鲁胺双酯中间体的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3412290B1 (en) * | 2006-03-27 | 2021-03-03 | The Regents of The University of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
| RU2548918C2 (ru) * | 2009-02-24 | 2015-04-20 | Медивэйшн Простейт Терапьютикс, Инк. | Специфические соединения диарилгидантоина и диарилтиогидантоина |
| CN101817787B (zh) * | 2009-02-26 | 2013-07-24 | 童友之 | 抗前列腺癌的雄性激素受体拮抗剂 |
| BR112012021406B1 (pt) * | 2010-02-24 | 2021-08-10 | Medivation Prostate Therapeutics Llc | Processos para a síntese dos compostos de diariltioidantoína e diarilidantoína |
| CN103159680A (zh) * | 2011-12-14 | 2013-06-19 | 爱美尼迪药物有限公司 | 咪唑二酮类化合物及其用途 |
| US9708289B2 (en) * | 2013-05-29 | 2017-07-18 | Hinova Pharmaceuticals Inc. | Imidazole diketone compound and use thereof |
| CN104341352A (zh) * | 2013-08-09 | 2015-02-11 | 南京衡杰生物科技有限公司 | 作为雄激素受体拮抗剂的二芳基乙内酰脲化合物及其应用 |
| CN104803918B (zh) * | 2014-01-26 | 2017-11-10 | 上海医药工业研究院 | 恩杂鲁胺的制备方法 |
| CN104016924B (zh) * | 2014-06-16 | 2016-04-13 | 上海鼎雅药物化学科技有限公司 | 一种“一锅法”合成恩杂鲁胺的方法 |
| RU2557235C1 (ru) * | 2014-07-08 | 2015-07-20 | Александр Васильевич Иващенко | Замещенные 2-тиоксо-имидазолидин-4-оны и их спироаналоги, противораковый активный компонент, фармацевтическая композиция, лекарственный препарат, способ лечения рака простаты |
-
2016
- 2016-10-17 CN CN201610901502.0A patent/CN107954936B/zh active Active
- 2016-12-20 PL PL16919556.7T patent/PL3527556T3/pl unknown
- 2016-12-20 CA CA3040785A patent/CA3040785C/en active Active
- 2016-12-20 FI FIEP16919556.7T patent/FI3527556T3/fi active
- 2016-12-20 EP EP16919556.7A patent/EP3527556B1/en active Active
- 2016-12-20 WO PCT/CN2016/110978 patent/WO2018072300A1/zh unknown
- 2016-12-20 HU HUE16919556A patent/HUE061557T2/hu unknown
- 2016-12-20 US US16/342,912 patent/US20200087261A1/en not_active Abandoned
- 2016-12-20 JP JP2019520547A patent/JP7241682B2/ja active Active
- 2016-12-20 PT PT169195567T patent/PT3527556T/pt unknown
- 2016-12-20 ES ES16919556T patent/ES2943011T3/es active Active
- 2016-12-20 AU AU2016426847A patent/AU2016426847B2/en active Active
- 2016-12-20 DK DK16919556.7T patent/DK3527556T3/da active
-
2017
- 2017-03-24 TW TW106109895A patent/TWI728077B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE061557T2 (hu) | 2023-07-28 |
| TW201815768A (zh) | 2018-05-01 |
| CA3040785C (en) | 2021-06-15 |
| JP2019532075A (ja) | 2019-11-07 |
| CN107954936A (zh) | 2018-04-24 |
| EP3527556A1 (en) | 2019-08-21 |
| FI3527556T3 (fi) | 2023-04-25 |
| CN107954936B (zh) | 2021-03-19 |
| EP3527556A4 (en) | 2020-04-29 |
| CA3040785A1 (en) | 2018-04-26 |
| JP7241682B2 (ja) | 2023-03-17 |
| TWI728077B (zh) | 2021-05-21 |
| AU2016426847A1 (en) | 2019-06-06 |
| ES2943011T3 (es) | 2023-06-08 |
| PT3527556T (pt) | 2023-05-02 |
| DK3527556T3 (da) | 2023-05-01 |
| WO2018072300A1 (zh) | 2018-04-26 |
| US20200087261A1 (en) | 2020-03-19 |
| AU2016426847B2 (en) | 2020-11-26 |
| EP3527556B1 (en) | 2023-01-25 |
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