PL352041A1 - Derivatives of isochynoline, pharmaceutical compositions containing these derivatives and method of obtaining an active substance - Google Patents

Derivatives of isochynoline, pharmaceutical compositions containing these derivatives and method of obtaining an active substance

Info

Publication number
PL352041A1
PL352041A1 PL00352041A PL35204100A PL352041A1 PL 352041 A1 PL352041 A1 PL 352041A1 PL 00352041 A PL00352041 A PL 00352041A PL 35204100 A PL35204100 A PL 35204100A PL 352041 A1 PL352041 A1 PL 352041A1
Authority
PL
Poland
Prior art keywords
derivatives
isochynoline
obtaining
pharmaceutical compositions
active substance
Prior art date
Application number
PL00352041A
Other languages
English (en)
Inventor
Imre Doman
Jozsef Barkoczy
Gyula Simig
Laszlo Poszavacz
Csaba Szantay
Maria Incze
Gabor Dornyei
Laszlo Balazs
Zoltan Greff
Peter Kotay-Nagy
Zoltan Ratkai
Peter Seres
Andras Bilkei-Gorzo
Istvan Gacsalyi
Gyorgy Levay
Karoly Tihanyi
Barnogel Judit Raczne
Andras Egyed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9902590A external-priority patent/HUP9902590A3/hu
Priority claimed from HU9902591A external-priority patent/HUP9902591A3/hu
Priority claimed from HU9902592A external-priority patent/HUP9902592A3/hu
Application filed filed Critical
Publication of PL352041A1 publication Critical patent/PL352041A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PL00352041A 1999-07-29 2000-07-28 Derivatives of isochynoline, pharmaceutical compositions containing these derivatives and method of obtaining an active substance PL352041A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU9902590A HUP9902590A3 (en) 1999-07-29 1999-07-29 3,4-dihydro isoquinolinium derivatives, pharmaceutical compositions containing them and process for producing them
HU9902591A HUP9902591A3 (en) 1999-07-29 1999-07-29 3,4-dihydro isoquinolinium derivatives, pharmaceutical compositions containing such active ingredients and process for producing them
HU9902592A HUP9902592A3 (en) 1999-07-29 1999-07-29 Isoquinoline derivatives, pharmaceutical compositions containing such active ingredients and process for producing them
PCT/HU2000/000087 WO2001009101A1 (en) 1999-07-29 2000-07-28 Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance

Publications (1)

Publication Number Publication Date
PL352041A1 true PL352041A1 (en) 2003-07-28

Family

ID=89998920

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00352041A PL352041A1 (en) 1999-07-29 2000-07-28 Derivatives of isochynoline, pharmaceutical compositions containing these derivatives and method of obtaining an active substance

Country Status (7)

Country Link
EP (1) EP1200410A1 (xx)
JP (1) JP2003506358A (xx)
AU (1) AU6308900A (xx)
CZ (1) CZ2002342A3 (xx)
PL (1) PL352041A1 (xx)
SK (1) SK1212002A3 (xx)
WO (1) WO2001009101A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03000966A (es) * 2002-02-28 2003-09-04 Pfizer Prod Inc Agentes antidiabeticos.
AR077223A1 (es) 2009-06-26 2011-08-10 Sanofi Aventis Sales de fumarato de un antagonista del receptor de histamina h3
CA3107453A1 (en) * 2018-07-23 2020-01-30 Ohio State Innovation Foundation Derivatives of papaverine that are effective hypoxic tumor radiosensitizers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH410007A (de) * 1961-04-21 1966-03-31 Hoffmann La Roche Verfahren zur Herstellung von tertiären Aminen
DE1902402A1 (de) * 1968-05-21 1969-11-27 Dresden Arzneimittel Verfahren zur Herstellung von 1-substituierten 6.7-Dimethoxy-isochinolinen
DE1902559A1 (de) * 1968-07-05 1970-03-26 Dresden Arzneimittel Verfahren zur Herstellung von 1-substituierten 3,4-Dihydro-6,7-dimethoxy-isochinolinen
GB1181959A (en) * 1969-01-30 1970-02-18 Dresden Arzneimittel 6,7-Dimethoxy-3,4-Dihydroisoquinoline Derivatives
GB8419658D0 (en) * 1984-08-01 1984-09-05 Wellcome Found Nitrogen containing heterocyclic compounds
HUT71407A (en) * 1994-05-03 1995-11-28 Egyt Gyogyszervegyeszeti Gyar Heterocyclic compounds, pharmaceutical compositions containing them, and process for producing the active components
EP0787493A1 (en) * 1996-02-03 1997-08-06 F. Hoffmann-La Roche Ag Tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
AU6308900A (en) 2001-02-19
WO2001009101A1 (en) 2001-02-08
SK1212002A3 (en) 2002-11-06
JP2003506358A (ja) 2003-02-18
EP1200410A1 (en) 2002-05-02
CZ2002342A3 (cs) 2002-06-12

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)