PL3453721T3 - Sposób wytwarzania aneksyny v - Google Patents
Sposób wytwarzania aneksyny vInfo
- Publication number
- PL3453721T3 PL3453721T3 PL18182321.2T PL18182321T PL3453721T3 PL 3453721 T3 PL3453721 T3 PL 3453721T3 PL 18182321 T PL18182321 T PL 18182321T PL 3453721 T3 PL3453721 T3 PL 3453721T3
- Authority
- PL
- Poland
- Prior art keywords
- annexin
- manufacture
- Prior art date
Links
- 102000000412 Annexin Human genes 0.000 title 1
- 108050008874 Annexin Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Marine Sciences & Fisheries (AREA)
- Transplantation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1516516.0A GB2542391A (en) | 2015-09-17 | 2015-09-17 | Process of manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3453721T3 true PL3453721T3 (pl) | 2022-11-07 |
Family
ID=54544424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16766559T PL3283506T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
| PL18182321.2T PL3453721T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16766559T PL3283506T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11773134B2 (pl) |
| EP (3) | EP3283506B1 (pl) |
| JP (5) | JP6689371B2 (pl) |
| CN (3) | CN116333031A (pl) |
| CA (2) | CA3193026A1 (pl) |
| DK (2) | DK3283506T3 (pl) |
| ES (2) | ES2920156T3 (pl) |
| GB (1) | GB2542391A (pl) |
| HK (1) | HK1251580B (pl) |
| PL (2) | PL3283506T3 (pl) |
| WO (1) | WO2017046391A2 (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2542391A (en) * | 2015-09-17 | 2017-03-22 | Annexin Pharmaceuticals Ab | Process of manufacture |
| EP3495376A1 (en) * | 2017-12-05 | 2019-06-12 | ChromaCon AG | Improved chromatographic process for cell culture harvest |
| EP3560945A1 (en) * | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
| JP7352555B2 (ja) * | 2018-08-31 | 2023-09-28 | 株式会社カネカ | 抗体または抗体様分子の精製方法 |
| TWI871300B (zh) * | 2019-01-28 | 2025-02-01 | 美商安進公司 | 藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程 |
| CN110669141A (zh) * | 2019-09-29 | 2020-01-10 | 杭州联科生物技术股份有限公司 | 一种别藻蓝蛋白(APC)与Annexin V蛋白偶联方法 |
| TW202146042A (zh) * | 2020-03-06 | 2021-12-16 | 瑞典商阿斯特捷利康公司 | 用於治療動脈和靜脈血栓形成的協同且靶向的組成物 |
| CN111378005B (zh) * | 2020-04-03 | 2021-08-17 | 安徽环球基因科技有限公司 | 一种可调式纯化蛋白装置 |
| CN112057623A (zh) * | 2020-06-03 | 2020-12-11 | 江苏靶标生物医药研究所有限公司 | 一种磷脂酰丝氨酸在制备治疗炎症性肠病药物中的应用 |
| KR20240111310A (ko) * | 2021-12-08 | 2024-07-16 | 훼링 비.브이. | 단백질 정제 방법 |
| CN114539383B (zh) * | 2022-02-24 | 2024-03-26 | 南京大学 | 一种人源膜联蛋白人源膜联蛋白a5突变体二聚体的晶体结构的制备方法和应用 |
| GB202207263D0 (en) * | 2022-05-18 | 2022-06-29 | Annexin Pharmaceuticals Ab | Therapeutic compositions |
| CN118001376A (zh) * | 2023-02-27 | 2024-05-10 | 上海萨美细胞技术有限公司 | 膜联蛋白a5在生发、育发、护发、防脱发以及治疗脱发中的用途和相关产品和药物组合物 |
| IL324669A (en) * | 2023-05-18 | 2026-01-01 | Annexin Pharmaceuticals Ab | Annexin A5 protein as a combination therapy with an anti-VEGF agent for use in the treatment of macular edema or retinal vein occlusion |
| WO2025086968A1 (zh) * | 2023-10-25 | 2025-05-01 | 上海萨美细胞技术有限公司 | 一种用于治疗肺纤维化的药物 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0209568B1 (en) * | 1985-01-10 | 1994-07-20 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing human lipocortin-like polypeptides |
| DE3643182A1 (de) * | 1986-12-18 | 1988-06-30 | Behringwerke Ag | Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4 |
| DE3939169A1 (de) * | 1989-11-27 | 1991-05-29 | Behringwerke Ag | Verfahren zur reinigung von lipocortinen |
| DE4003773A1 (de) * | 1990-02-08 | 1991-08-14 | Behringwerke Ag | Verfahren zur reinigung von lipocortinen |
| DE4012341A1 (de) * | 1990-04-18 | 1991-10-24 | Behringwerke Ag | Monoklonale antikoerper gegen pp4, verfahren zu ihrer herstellung und ihre verwendung |
| US5968477A (en) * | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
| JP2000239299A (ja) | 1999-02-15 | 2000-09-05 | Snow Brand Milk Prod Co Ltd | 新規蛋白質及びその製造方法 |
| US6492327B2 (en) * | 2000-12-19 | 2002-12-10 | Sulzer Biologics Inc. | Isolation of purified TGF- β1 and TGF -β2 from bone tissue |
| GB0101300D0 (en) * | 2001-01-18 | 2001-02-28 | Univ Cambridge Tech | Primordial germ cell genes |
| US7635680B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaceuticals, Inc. | Attenuation of reperfusion injury |
| US7645739B2 (en) | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
| EP1379266B1 (en) * | 2001-02-21 | 2007-04-18 | SurroMed, Inc. | Modified annexin proteins and prevention and treatment of thrombosis |
| EP1389090A2 (en) * | 2001-04-26 | 2004-02-18 | Board of Regents, The University of Texas System | Diagnostic imaging compositions, their methods of synthesis and use |
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2015
- 2015-09-17 GB GB1516516.0A patent/GB2542391A/en not_active Withdrawn
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2016
- 2016-09-16 DK DK16766559.5T patent/DK3283506T3/en active
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- 2016-09-16 CN CN202211002553.1A patent/CN116333031A/zh active Pending
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- 2016-09-16 EP EP18182321.2A patent/EP3453721B1/en active Active
- 2016-09-16 WO PCT/EP2016/072066 patent/WO2017046391A2/en not_active Ceased
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