PL335865A1 - Derivative of quinoline-2-carboxylic acid and application thereof as an antagonist of stimulating amino acids - Google Patents
Derivative of quinoline-2-carboxylic acid and application thereof as an antagonist of stimulating amino acidsInfo
- Publication number
- PL335865A1 PL335865A1 PL98335865A PL33586598A PL335865A1 PL 335865 A1 PL335865 A1 PL 335865A1 PL 98335865 A PL98335865 A PL 98335865A PL 33586598 A PL33586598 A PL 33586598A PL 335865 A1 PL335865 A1 PL 335865A1
- Authority
- PL
- Poland
- Prior art keywords
- quinoline
- antagonist
- derivative
- application
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706294.7A GB9706294D0 (en) | 1997-03-26 | 1997-03-26 | Heterocyclic compound |
| PCT/EP1998/001700 WO1998042673A1 (en) | 1997-03-26 | 1998-03-24 | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL335865A1 true PL335865A1 (en) | 2000-05-22 |
Family
ID=10809909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL98335865A PL335865A1 (en) | 1997-03-26 | 1998-03-24 | Derivative of quinoline-2-carboxylic acid and application thereof as an antagonist of stimulating amino acids |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0971896A1 (pt) |
| JP (1) | JP2001518901A (pt) |
| KR (1) | KR20010005567A (pt) |
| CN (1) | CN1257482A (pt) |
| AP (1) | AP9901659A0 (pt) |
| AU (1) | AU731394B2 (pt) |
| BR (1) | BR9808424A (pt) |
| CA (1) | CA2284710A1 (pt) |
| EA (1) | EA199900755A1 (pt) |
| GB (1) | GB9706294D0 (pt) |
| HU (1) | HUP0001661A3 (pt) |
| ID (1) | ID24306A (pt) |
| IL (1) | IL131919A0 (pt) |
| IS (1) | IS5186A (pt) |
| NO (1) | NO994679L (pt) |
| NZ (1) | NZ337793A (pt) |
| PL (1) | PL335865A1 (pt) |
| TR (1) | TR199902315T2 (pt) |
| WO (1) | WO1998042673A1 (pt) |
| YU (1) | YU47699A (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917822D0 (en) * | 1999-07-29 | 1999-09-29 | Imperial College | Nmda antagonist |
| DE10132725A1 (de) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituierte γ-Lactonverbindungen |
| DE10137487A1 (de) | 2001-08-03 | 2003-03-27 | Gruenenthal Gmbh | Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate |
| DE10306202A1 (de) | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
| JP4360891B2 (ja) | 2003-12-09 | 2009-11-11 | アルパイン株式会社 | 放送受信機能を備えた電子装置およびその装置における電子番組ガイドの表示方法 |
| RU2451014C2 (ru) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Новое производное гетероциклиден ацетамида |
| PT1908753E (pt) * | 2005-07-22 | 2015-02-06 | Mochida Pharm Co Ltd | Novo derivado acetamida de heterociclideno |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| JP7305560B2 (ja) | 2017-06-12 | 2023-07-10 | グリテック， エルエルシー | Ｎｍｄａアンタゴニスト及びｄ２／５ｈｔ２ａ又は選択的５ｈｔ２ａアンタゴニストによるうつ病の治療 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE147732T1 (de) * | 1989-03-08 | 1997-02-15 | Merck Sharp & Dohme | Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten |
| PL186781B1 (pl) * | 1995-09-29 | 2004-02-27 | Glaxo Wellcome Spa | Nowy związek, pochodna tetrahydrochinoliny, sposób wytwarzania pochodnej tetrahydrochinoliny, środek farmaceutyczny i zastosowanie |
| GB9617305D0 (en) * | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
-
1997
- 1997-03-26 GB GBGB9706294.7A patent/GB9706294D0/en active Pending
-
1998
- 1998-03-24 PL PL98335865A patent/PL335865A1/xx unknown
- 1998-03-24 AP APAP/P/1999/001659A patent/AP9901659A0/en unknown
- 1998-03-24 JP JP54323498A patent/JP2001518901A/ja active Pending
- 1998-03-24 CN CN98805302A patent/CN1257482A/zh active Pending
- 1998-03-24 YU YU47699A patent/YU47699A/sh unknown
- 1998-03-24 EP EP98919133A patent/EP0971896A1/en not_active Withdrawn
- 1998-03-24 AU AU72094/98A patent/AU731394B2/en not_active Ceased
- 1998-03-24 ID IDW991108A patent/ID24306A/id unknown
- 1998-03-24 HU HU0001661A patent/HUP0001661A3/hu unknown
- 1998-03-24 NZ NZ337793A patent/NZ337793A/en unknown
- 1998-03-24 IL IL13191998A patent/IL131919A0/xx unknown
- 1998-03-24 CA CA002284710A patent/CA2284710A1/en not_active Abandoned
- 1998-03-24 EA EA199900755A patent/EA199900755A1/ru unknown
- 1998-03-24 BR BR9808424-0A patent/BR9808424A/pt not_active IP Right Cessation
- 1998-03-24 WO PCT/EP1998/001700 patent/WO1998042673A1/en not_active Application Discontinuation
- 1998-03-24 KR KR1019997008630A patent/KR20010005567A/ko not_active Application Discontinuation
- 1998-03-24 TR TR1999/02315T patent/TR199902315T2/xx unknown
-
1999
- 1999-09-17 IS IS5186A patent/IS5186A/is unknown
- 1999-09-24 NO NO994679A patent/NO994679L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998042673A1 (en) | 1998-10-01 |
| HUP0001661A3 (en) | 2001-12-28 |
| EA199900755A1 (ru) | 2000-08-28 |
| JP2001518901A (ja) | 2001-10-16 |
| NO994679L (no) | 1999-11-24 |
| CA2284710A1 (en) | 1998-10-01 |
| NO994679D0 (no) | 1999-09-24 |
| ID24306A (id) | 2000-07-13 |
| IS5186A (is) | 1999-09-17 |
| NZ337793A (en) | 2001-02-23 |
| GB9706294D0 (en) | 1997-05-14 |
| TR199902315T2 (xx) | 2000-05-22 |
| BR9808424A (pt) | 2000-05-23 |
| CN1257482A (zh) | 2000-06-21 |
| IL131919A0 (en) | 2001-03-19 |
| YU47699A (sh) | 2001-12-26 |
| KR20010005567A (ko) | 2001-01-15 |
| HUP0001661A2 (hu) | 2000-09-28 |
| AU7209498A (en) | 1998-10-20 |
| AU731394B2 (en) | 2001-03-29 |
| AP9901659A0 (en) | 1999-09-30 |
| EP0971896A1 (en) | 2000-01-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL337698A1 (en) | Derivatives of 4-bromo- or iodo-phenylaminobenzhydroxamic acid and their application as mek inhibitors | |
| ZA989740B (en) | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | |
| ZA9811327B (en) | Compositions and methods for altering amino acid content of proteins | |
| IL135673A0 (en) | Therapeutic uses of quinoline derivatives | |
| PL330482A1 (en) | Novel amino acid derivatives and their application as thrombosin inhibitors | |
| HUP0000810A3 (en) | Proteins with enhanced levels of essential amino acids | |
| PL335974A1 (en) | Method of orally administering proteins | |
| PL309972A1 (en) | Synthetic stimulating amino acids and methods of obtaining them | |
| IL110821A0 (en) | Carbocyclic and heterocyclic fused-ring quinolinecarboxylic acids and pharmaceutical compositions comprising them | |
| PL339660A1 (en) | Derivatives of amidocarboxylic acids | |
| IL129839A0 (en) | Method of preparing amino carboxylic acids | |
| US5656608B1 (en) | Amino acid compositions and methods of treatment using same | |
| HUP9901630A3 (en) | Indole-2,3-dione-3-oxime derivatives as antagonists of excitatory amino acids, preparation and use thereof | |
| GB2343117B (en) | Benzimidazole pharmaceutical composition and process of preparation | |
| HUP9801838A3 (en) | Indole derivatives as antagonists of excitatory amino acids | |
| PL335865A1 (en) | Derivative of quinoline-2-carboxylic acid and application thereof as an antagonist of stimulating amino acids | |
| PL307846A1 (en) | Substituted heterocyclic amidoesters of carboxylic acids, methods of obtaining them and their application as therapeutic agents | |
| HK1025901A1 (en) | Method of enhancing bioavailability of fexofenadine and its derivatives | |
| EP0939643A4 (en) | IMMUNOMODULATORY COMPOUNDS COMPRISING D ISOMERS OF AMINO ACIDS | |
| PL341205A1 (en) | Method of obtaining l-dihydroorotic acid and application thereof | |
| PL335031A1 (en) | Compound and method of obtaining substituted 4-phenyl-4-cyanocyclohexanic acids | |
| PL343780A1 (en) | Method of obtaining l-amino acids | |
| PL317853A1 (en) | Derivatives of amino acids | |
| AU3996799A (en) | Alpha amino acid composition and method for the treatment of skin | |
| IL122919A (en) | Preparation of 1-alkyl-pyrazole-5- carboxylic acid esters |