AU7209498A - Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist - Google Patents
Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonistInfo
- Publication number
- AU7209498A AU7209498A AU72094/98A AU7209498A AU7209498A AU 7209498 A AU7209498 A AU 7209498A AU 72094/98 A AU72094/98 A AU 72094/98A AU 7209498 A AU7209498 A AU 7209498A AU 7209498 A AU7209498 A AU 7209498A
- Authority
- AU
- Australia
- Prior art keywords
- quinoline
- antagonist
- carboxylic acid
- amino acids
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706294.7A GB9706294D0 (en) | 1997-03-26 | 1997-03-26 | Heterocyclic compound |
| GB9706294 | 1997-03-26 | ||
| PCT/EP1998/001700 WO1998042673A1 (en) | 1997-03-26 | 1998-03-24 | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7209498A true AU7209498A (en) | 1998-10-20 |
| AU731394B2 AU731394B2 (en) | 2001-03-29 |
Family
ID=10809909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU72094/98A Ceased AU731394B2 (en) | 1997-03-26 | 1998-03-24 | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0971896A1 (en) |
| JP (1) | JP2001518901A (en) |
| KR (1) | KR20010005567A (en) |
| CN (1) | CN1257482A (en) |
| AP (1) | AP9901659A0 (en) |
| AU (1) | AU731394B2 (en) |
| BR (1) | BR9808424A (en) |
| CA (1) | CA2284710A1 (en) |
| EA (1) | EA199900755A1 (en) |
| GB (1) | GB9706294D0 (en) |
| HU (1) | HUP0001661A3 (en) |
| ID (1) | ID24306A (en) |
| IL (1) | IL131919A0 (en) |
| IS (1) | IS5186A (en) |
| NO (1) | NO994679L (en) |
| NZ (1) | NZ337793A (en) |
| PL (1) | PL335865A1 (en) |
| TR (1) | TR199902315T2 (en) |
| WO (1) | WO1998042673A1 (en) |
| YU (1) | YU47699A (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917822D0 (en) * | 1999-07-29 | 1999-09-29 | Imperial College | Nmda antagonist |
| DE10132725A1 (en) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituted γ-lactone compounds |
| DE10137487A1 (en) * | 2001-08-03 | 2003-03-27 | Gruenenthal Gmbh | Substituted 5,6,6a, 11b-tetrahydro-7-oxa-6-aza-benzo [c] fluorene-6-carboxylic acid derivatives |
| DE10306202A1 (en) | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | 2-(hetero)aryl-2-(N-((hetero)aryl)-amino)-acetic acid derivatives useful e.g. for treating anxiety, inflammation, allergy, depression, diarrhea or especially pain is NMDA antagonist |
| JP4360891B2 (en) | 2003-12-09 | 2009-11-11 | アルパイン株式会社 | Electronic device having broadcast receiving function and display method of electronic program guide in the device |
| KR101136183B1 (en) | 2005-07-22 | 2012-04-17 | 모찌다 세이야쿠 가부시끼가이샤 | Novel heterocyclidene acetamide derivative |
| RU2451014C2 (en) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Novel heterocyclidene acetamide derivative |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| JP7305560B2 (en) | 2017-06-12 | 2023-07-10 | グリテック， エルエルシー | Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0386839B1 (en) * | 1989-03-08 | 1997-01-15 | Merck Sharp & Dohme Ltd. | Tetrahydroquinoline derivatives useful for neurodegenerative disorders |
| TR199800531T1 (en) * | 1995-09-29 | 1998-06-22 | Glaxo Wellcome Spa | Tetrahydroquinolines as NMDA antagonists. |
| GB9617305D0 (en) * | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
-
1997
- 1997-03-26 GB GBGB9706294.7A patent/GB9706294D0/en active Pending
-
1998
- 1998-03-24 CA CA002284710A patent/CA2284710A1/en not_active Abandoned
- 1998-03-24 AP APAP/P/1999/001659A patent/AP9901659A0/en unknown
- 1998-03-24 ID IDW991108A patent/ID24306A/en unknown
- 1998-03-24 AU AU72094/98A patent/AU731394B2/en not_active Ceased
- 1998-03-24 JP JP54323498A patent/JP2001518901A/en active Pending
- 1998-03-24 EP EP98919133A patent/EP0971896A1/en not_active Withdrawn
- 1998-03-24 YU YU47699A patent/YU47699A/en unknown
- 1998-03-24 CN CN98805302A patent/CN1257482A/en active Pending
- 1998-03-24 IL IL13191998A patent/IL131919A0/en unknown
- 1998-03-24 TR TR1999/02315T patent/TR199902315T2/en unknown
- 1998-03-24 HU HU0001661A patent/HUP0001661A3/en unknown
- 1998-03-24 NZ NZ337793A patent/NZ337793A/en unknown
- 1998-03-24 BR BR9808424-0A patent/BR9808424A/en not_active IP Right Cessation
- 1998-03-24 KR KR1019997008630A patent/KR20010005567A/en not_active Application Discontinuation
- 1998-03-24 EA EA199900755A patent/EA199900755A1/en unknown
- 1998-03-24 PL PL98335865A patent/PL335865A1/en unknown
- 1998-03-24 WO PCT/EP1998/001700 patent/WO1998042673A1/en not_active Application Discontinuation
-
1999
- 1999-09-17 IS IS5186A patent/IS5186A/en unknown
- 1999-09-24 NO NO994679A patent/NO994679L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB9706294D0 (en) | 1997-05-14 |
| ID24306A (en) | 2000-07-13 |
| PL335865A1 (en) | 2000-05-22 |
| TR199902315T2 (en) | 2000-05-22 |
| AP9901659A0 (en) | 1999-09-30 |
| HUP0001661A3 (en) | 2001-12-28 |
| NZ337793A (en) | 2001-02-23 |
| JP2001518901A (en) | 2001-10-16 |
| NO994679L (en) | 1999-11-24 |
| WO1998042673A1 (en) | 1998-10-01 |
| IL131919A0 (en) | 2001-03-19 |
| CN1257482A (en) | 2000-06-21 |
| AU731394B2 (en) | 2001-03-29 |
| EP0971896A1 (en) | 2000-01-19 |
| KR20010005567A (en) | 2001-01-15 |
| BR9808424A (en) | 2000-05-23 |
| EA199900755A1 (en) | 2000-08-28 |
| NO994679D0 (en) | 1999-09-24 |
| HUP0001661A2 (en) | 2000-09-28 |
| YU47699A (en) | 2001-12-26 |
| CA2284710A1 (en) | 1998-10-01 |
| IS5186A (en) | 1999-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB9623908D0 (en) | Amino acid derivatives | |
| PL330482A1 (en) | Novel amino acid derivatives and their application as thrombosin inhibitors | |
| AU2853095A (en) | Synthetic excitatory amino acids | |
| AU6257594A (en) | Indole derivatives as antagonists of excitatory amino acids | |
| AU7038296A (en) | Oximesulfonic acid esters and the use thereof as latent sulfonic acids | |
| AU1433901A (en) | Excitatory amino acid derivatives | |
| HUP9901630A3 (en) | Indole-2,3-dione-3-oxime derivatives as antagonists of excitatory amino acids, preparation and use thereof | |
| AU5727296A (en) | 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents | |
| HUP0003484A3 (en) | Pyrrolidine-3-crboxylic acid derivatives and their use as endothelin antagonists | |
| IL124487A0 (en) | Excitatory amino acid derivatives | |
| AU7209498A (en) | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist | |
| AU5836498A (en) | N-acyl-hydroxyamino acid esters and their use | |
| ZA9811655B (en) | Phenylaminoalkylcarboxylic acid derivatives and pharmaceutical compositions comprising the same | |
| AU7940598A (en) | Quinolone carboxylic acid derivatives | |
| AU5031598A (en) | Immune-modulation with amino acids | |
| AU6131094A (en) | Nucleoside derivatives and their use as excitatory amino acid antagonists | |
| AU3278195A (en) | Excitatory amino acid receptor antagonists | |
| AU3923000A (en) | Agp-1 fusion protein compositions and methods | |
| AU1684099A (en) | Amino acid derivatives | |
| AU5050198A (en) | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | |
| AU6120298A (en) | 2-peperazinone-1-acetic acid derivatives and their use | |
| AU2792695A (en) | Amino acid derivatives and their use as pesticides | |
| AU6473098A (en) | Difluoronucleoside phosphonic acids and derivatives thereof | |
| AU7657794A (en) | Indole derivatives as antagonists of excitatory amino acids | |
| AU4485296A (en) | Amino acid amide derivatives and their use as pesticides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |