PL3233875T3 - Oddzielanie 2’-FL z bulionu fermentacyjnego - Google Patents

Oddzielanie 2’-FL z bulionu fermentacyjnego

Info

Publication number
PL3233875T3
PL3233875T3 PL15869380.4T PL15869380T PL3233875T3 PL 3233875 T3 PL3233875 T3 PL 3233875T3 PL 15869380 T PL15869380 T PL 15869380T PL 3233875 T3 PL3233875 T3 PL 3233875T3
Authority
PL
Poland
Prior art keywords
separation
fermentation broth
broth
fermentation
Prior art date
Application number
PL15869380.4T
Other languages
English (en)
Inventor
Gyula Dekany
Györgyi OSZTROVSZKY
Martin MATWIEJUK
Pierre CHASSAGNE
Markus Hederos
Original Assignee
Glycom A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom A/S filed Critical Glycom A/S
Publication of PL3233875T3 publication Critical patent/PL3233875T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01069—Galactoside 2-alpha-L-fucosyltransferase (2.4.1.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL15869380.4T 2014-12-16 2015-12-16 Oddzielanie 2’-FL z bulionu fermentacyjnego PL3233875T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201470786 2014-12-16
PCT/DK2015/050396 WO2016095924A1 (en) 2014-12-16 2015-12-16 Separation of 2'-fl from a fermentation broth

Publications (1)

Publication Number Publication Date
PL3233875T3 true PL3233875T3 (pl) 2023-01-23

Family

ID=56125970

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15869380.4T PL3233875T3 (pl) 2014-12-16 2015-12-16 Oddzielanie 2’-FL z bulionu fermentacyjnego

Country Status (7)

Country Link
US (2) US10676770B2 (pl)
EP (2) EP4151645A3 (pl)
DE (1) DE202015009775U1 (pl)
DK (1) DK3233875T3 (pl)
ES (1) ES2933616T3 (pl)
PL (1) PL3233875T3 (pl)
WO (1) WO2016095924A1 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11384110B2 (en) 2016-10-31 2022-07-12 Glycom A/S Method for removing residual organic solvent from a crystalline oligosaccharide
WO2018164937A1 (en) 2017-03-06 2018-09-13 Dupont Nutrition Biosciences Aps Process for crystallizing 2'-fucosyllactose and related compositions
EP3596095A4 (en) * 2017-03-06 2021-01-27 DuPont Nutrition Biosciences ApS 2'-FUCOSYLLACTOSE CRYSTALLIZATION PROCESS AND ASSOCIATED COMPOSITIONS
US11214588B2 (en) 2017-06-30 2022-01-04 Glycom A/S Synthesis of oligosaccharides
CN110914284A (zh) 2017-07-12 2020-03-24 格礼卡姆股份公司 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物
KR101953375B1 (ko) * 2017-11-20 2019-02-28 고려대학교 산학협력단 다양하고 신규한 퓨코실 올리고당의 제조법 및 이의 용도
AU2019362595A1 (en) 2018-10-18 2021-04-29 Basf Se Crystalline form II of 2'-O-fucosyllactose, process for its preparation, nutritional, cosmetic or pharmaceutical formulation containing the same
CA3136224A1 (en) * 2019-04-09 2020-10-15 Plexxikon Inc. Condensed azines for ep300 or cbp modulation and indications therefor
EP3741770A1 (en) 2019-05-21 2020-11-25 Jennewein Biotechnologie GmbH Purification of oligosaccharides from a fermentation broth by using filtration
CN110592162A (zh) * 2019-08-15 2019-12-20 安徽天凯生物科技有限公司 一种产2’-岩藻基乳糖菌株最佳发酵条件的构建方法
AU2021211904A1 (en) 2020-01-23 2022-07-14 Glycom A/S HMO production
AU2021209394A1 (en) 2020-01-23 2022-07-14 Glycom A/S HMO production
BR112022014367A2 (pt) 2020-01-23 2022-09-13 Glycom As Produção de hmo
JP2023511524A (ja) 2020-01-23 2023-03-20 グリコム・アクティーゼルスカブ Ｈｍｏ産生
EP4118089A4 (en) * 2020-03-12 2024-05-01 Glycom A/S CRYSTALLIZATION OF 2'-FL
MX2023007001A (es) * 2020-12-18 2023-06-26 Glycom As Remocion de biomasa por centrifugacion.
DK180952B1 (en) 2020-12-22 2022-08-10 Glycom As A dfl-producing strain
US20240102063A1 (en) 2021-01-22 2024-03-28 Glycom A/S New major facilitator superfamily (mfs) protein (fred) in production of sialylated hmos
CN112920234B (zh) * 2021-01-27 2022-03-29 南开大学 一种2′-岩藻糖基乳糖的富集纯化方法
CN117355228A (zh) 2021-04-30 2024-01-05 帝斯曼知识产权资产管理有限公司 砷含量低的婴幼儿配方品
EP4341277A1 (en) 2021-05-17 2024-03-27 DSM IP Assets B.V. Microbial strain expressing an invertase/sucrose hydrolase
DK181497B1 (en) 2021-05-17 2024-03-12 Dsm Ip Assets Bv ENHANCING FORMATION OF THE HMOS LNT AND/OR LNnT BY MODIFYING LACTOSE IMPORT IN THE CELL
BE1029437B1 (nl) 2021-06-15 2023-07-31 Dsm Ip Assets Bv Scheiding van moedermelkoligosachariden uit een fermentatiebouillon
WO2022263424A1 (en) 2021-06-15 2022-12-22 Dsm Ip Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
WO2022263425A1 (en) 2021-06-15 2022-12-22 Dsm Ip Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
WO2022263406A1 (en) 2021-06-15 2022-12-22 Dsm Ip Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
CN114032261A (zh) * 2021-10-09 2022-02-11 中国科学院合肥物质科学研究院 一种降解发酵液中乳糖获得高纯度岩藻糖基乳糖的方法
DK202170552A1 (en) 2021-11-11 2023-09-01 Dsm Ip Assets Bv Combined fermentation process for producing one or more human milk oligosaccharide(s) (hmo(s))
KR20240002283A (ko) * 2022-06-28 2024-01-05 주식회사 삼양사 2’-푸코실락토오스 제조방법
DK202201117A1 (en) 2022-12-09 2024-08-08 Dsm Ip Assets Bv Genetically modified udp-n-acetylgalactosamine producing cells

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US5106967A (en) 1988-05-05 1992-04-21 The Procter & Gamble Company Functional sugar substitutes with reduced calories
US5051541A (en) * 1990-03-23 1991-09-24 Thomas & Betts Corporation Plastic electrical connector for liquidtight conduit
US5929037A (en) 1995-06-07 1999-07-27 Alberta Research Council Modified α-D-Glcρ-(1-2)-α-D-Glcρ-(1-3)-α-D-Glcρ-analogues
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
ES2698398T3 (es) 2001-06-11 2019-02-04 Kyowa Hakko Bio Co Ltd Cristales de oligosacáridos y procesos para la preparación de los mismos
ITFI20030275A1 (it) 2003-10-29 2005-04-30 Inalco Spa Processo per la preparazione del galattosio
IT1392456B1 (it) 2008-12-18 2012-03-09 Inalco Spa Processo per la sintesi di di- o oligosaccaridi l-fucosilati e loro nuovi intermedi 2,3,4-tribenzil-fucosil-derivati.
MY183602A (en) 2008-12-19 2021-03-02 Chr Hansen Hmo Gmbh Synthesis of fucosylated compounds
CA2798675A1 (en) 2010-06-01 2011-12-08 Glycom A/S Polymorphs of 2'-o-fucosyllactose and producing thereof
EP4242320A3 (en) 2010-07-12 2023-11-29 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
IT1405680B1 (it) * 2010-09-13 2014-01-24 Inalco Spa Processo per la produzione di l-fucosio.
DK2479263T3 (da) 2011-01-20 2014-02-03 Jennewein Biotechnologie Gmbh Nye fucosyltransferaser og deres anvendelser
JP6047505B2 (ja) * 2011-02-16 2016-12-21 グリコシン リミテッド ライアビリティー カンパニー 操作された細菌におけるヒト乳オリゴ糖の生合成
FR2978773B1 (fr) 2011-08-01 2015-01-16 Snf Sas Nouveau procede de fabrication de dextran, solution de dextran obtenue et utilisations
GB201121615D0 (en) 2011-12-15 2012-01-25 Glycom As Synthesis of n-acetyl-d-neuraminic acid
ITFI20120143A1 (it) * 2012-07-12 2014-01-13 Inalco S A S Di Giovanni Cipollett I & C Polimorfi idrati e anidri del 2'-o-fucosillattosio e loro metodi di produzione.
US9163050B2 (en) 2012-08-06 2015-10-20 Orochem Technologies, Inc. Mannose production from palm kernel meal using simulated moving bed separation
WO2014069625A1 (ja) 2012-11-01 2014-05-08 協和発酵バイオ株式会社 オリゴ糖の結晶およびその製造方法
WO2014086373A1 (en) 2012-12-07 2014-06-12 Glycom A/S Crystallisation of human milk oligosaccharides (hmo)
DE202015009782U1 (de) 2014-06-11 2020-02-10 Glycom A/S Trennung von 2'-O-Fucosyllactose aus Fermentationsbrühe

Also Published As

Publication number Publication date
EP4151645A3 (en) 2023-06-21
US20170369920A1 (en) 2017-12-28
EP3233875A1 (en) 2017-10-25
US12060594B2 (en) 2024-08-13
EP3233875A4 (en) 2018-07-25
DK3233875T3 (en) 2022-12-19
US20200299740A1 (en) 2020-09-24
EP3233875B1 (en) 2022-10-05
ES2933616T3 (es) 2023-02-10
DE202015009775U1 (de) 2020-02-05
WO2016095924A1 (en) 2016-06-23
EP4151645A2 (en) 2023-03-22
US10676770B2 (en) 2020-06-09

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